Nanosystems
Gene Delivery
Drug Delivery
Targeted Cancer Therapy
Development and characterization of novel inorganic-, lipid- and polymer-based nanosystems that have the ability to specifically and efficiently deliver different therapeutic agents, such as genetic material and drugs, into target cells
Generations of combined multitarget antitumor strategies, acting in several signaling pathways of carcinogenesis
assessment of the in vitro and in vivo antitumor activity of the combined and individual strategies
and clarification of the underlying tumor cell death mechanisms
Cancer remains a major health problem, being a leading cause of death worldwide. Despite the ongoing efforts, current treatment options are largely insufficient, being associated to multiple limitations. This fact highlight the urgent need for the development of novel therapeutic interventions, just like those involving the combination of gene therapy and chemotherapy.
Nanotechnology-based systems could greatly contribute to the success of these combined antitumor strategies, since nanosystems, namely targeted-nanosystems, have the capacity to specifically and efficiently deliver the therapeutic molecules into target cells.
The main goal of our group is to generate novel delivery nanosystems that have the ability to mediate new combined multi-target antitumor strategies, such as those involving genetic material and drugs, in order to obtain a higher therapeutic efficacy than that achieved with current treatment options.
Our principal objectives are:
Information about journal articles, updated at 22-12-2024, from platform CIÊNCIAVITAE.
Targeted downregulation of MYC mediated by a highly efficient lactobionic acid-based glycoplex to enhance chemosensitivity in human hepatocellular carcinoma cells
Santo, Daniela; Mendonça, Patrícia V.; Serra, Arménio C.; Coelho, Jorge F.J.; Faneca, Henrique, 2023. International Journal of Pharmaceutics. 122865 - 122882. 637. 2023. http://dx.doi.org/10.1016/j.ijpharm.2023.122865 . 10.1016/j.ijpharm.2023.122865 . International Journal of Pharmaceutics
Glycopolymers Mediate Suicide Gene Therapy in ASGPR-Expressing Hepatocellular Carcinoma Cells in Tandem with Docetaxel
Santo, Daniela; Cordeiro, Rosemeyre A.; Mendonça, Patrícia V.; Serra, Arménio C.; Coelho, Jorge F. J.; Faneca, Henrique, 2023. Biomacromolecules. 1274 - 1286. 3. 24. 2023. http://dx.doi.org/10.1021/acs.biomac.2c01329 . 10.1021/acs.biomac.2c01329 . Biomacromolecules
Polymer- and lipid-based gene delivery technology for CAR T cell therapy
Pinto, Inês S.; Cordeiro, Rosemeyre A.; Faneca, Henrique, 2023. Journal of Controlled Release. 196 - 215. 353. 2023. http://dx.doi.org/10.1016/j.jconrel.2022.11.038 . 10.1016/j.jconrel.2022.11.038 . published Journal of Controlled Release
Engineering silica-polymer hybrid nanosystems for dual drug and gene delivery
Cordeiro, Rosemeyre A.; Mendonça, Patrícia V.; Coelho, Jorge; Faneca, Henrique, 2022. Biomaterials Advances. 212742 - 212754. 135. 2022. http://dx.doi.org/10.1016/j.bioadv.2022.212742 . 10.1016/j.bioadv.2022.212742 . Biomaterials Advances
Expanding the use of affordable CuSO4·5H2O in ATRP techniques in homogeneous media
Ribeiro, Jessica P.M.; Mendonça, Patrícia V.; Santo, Daniela; De Bon, Francesco; Faneca, Henrique; Guliashvili, Tamaz; Coelho, Jorge F.J.; Serra, Arménio C., 2022. Polymer. 124526 - 124534. 241. 2022. http://dx.doi.org/10.1016/j.polymer.2022.124526 . 10.1016/j.polymer.2022.124526 . Polymer
Fabrication of 3D scaffolds based on fully biobased unsaturated polyester resins by microstereo-lithography
Gonçalves, Filipa A M M; Fonseca, Ana C; Cordeiro, Rosemeyre; Piedade, Ana P; Faneca, Henrique; Serra, Arménio; Coelho, Jorge F J, 2022. Biomedical Materials. 025010 - 025021. 2. 17. 2022. http://dx.doi.org/10.1088/1748-605x/ac4b46 . 10.1088/1748-605x/ac4b46 . published Biomedical Materials
Stem cell membrane-coated abiotic nanomaterials for biomedical applications
Ferreira-Faria, Inês; Yousefiasl, Satar; Macário-Soares, Ana; Pereira-Silva, Miguel; Peixoto, Diana; Zafar, Hajra; Raza, Faisal; et al, 2022. Journal of Controlled Release. 174 - 197. 351. 2022. http://dx.doi.org/10.1016/j.jconrel.2022.09.012 . 10.1016/j.jconrel.2022.09.012 . published Journal of Controlled Release
Novel Non-Viral Vectors Based on Pluronic® F68PEI with Application in Oncology Field
Silva, Inês; Domingues, Cátia; Jarak, Ivana; Carvalho, Rui A.; Cordeiro, Rosemeyre A.; Dourado, Marília; Veiga, Francisco; Faneca, Henrique; Figueiras, Ana, 2022. Polymers. 5315 - 5329. 23. 14. 2022. http://dx.doi.org/10.3390/polym14235315 . 10.3390/polym14235315 . published Polymers
Triantennary GalNAc-Functionalized Multi-Responsive Mesoporous Silica Nanoparticles for Drug Delivery Targeted at Asialoglycoprotein Receptor
Cordeiro, Rosemeyre; Carvalho, Ana; Durães, Luísa; Faneca, Henrique, 2022. International Journal of Molecular Sciences. 6243 - 6260. 11. 23. 2022. http://dx.doi.org/10.3390/ijms23116243 . 10.3390/ijms23116243 . International Journal of Molecular Sciences
Combining gene therapy with other therapeutic strategies and imaging agents for cancer theranostics
Azevedo, Alexandro; Farinha, Dina; Geraldes, Carlos; Faneca, Henrique (4E1F-D234-7CD6), 2021. International Journal of Pharmaceutics. 120905 - 120928. 606. 2021. http://dx.doi.org/10.1016/j.ijpharm.2021.120905 . 10.1016/j.ijpharm.2021.120905 . published International Journal of Pharmaceutics
Non-Viral Gene Delivery Systems
Faneca, Henrique, 2021. Pharmaceutics. 446 - 449. 04. 13. 2021. https://doi.org/10.3390/ pharmaceutics13040446 . 10.3390/pharmaceutics13040446 . published Pharmaceutics
Recent advances in peptide-targeted micelleplexes: Current developments and future perspectives
Costa, Diana; Santo, Daniela; Domingues, Cátia; Veiga, Francisco; Faneca, Henrique (4E1F-D234-7CD6); Figueiras, Ana, 2021. International Journal of Pharmaceutics. 120362 - 120382. 597. 2021. https://doi.org/10.1016/j.ijpharm.2021.120362 . 10.1016/j.ijpharm.2021.120362 . published International Journal of Pharmaceutics
A Combined Antitumor Strategy Mediated by a New Targeted Nanosystem to Hepatocellular Carcinoma
Farinha, Dina; Michael Migawa; Sarmento-Ribeiro, AB; Faneca, Henrique, 2021. International Journal of Nanomedicine. 3385 - 3405. 16. 2021. https://doi.org/10.2147/IJN.S302288 . 10.2147/IJN.S302288 . published International Journal of Nanomedicine
Supercritically dried superparamagnetic mesoporous silica nanoparticles for cancer theranostics
Vaz-Ramos, Joana; Cordeiro, Rosemeyre; Castro, M. Margarida C.A.; Geraldes, Carlos F.G.C.; Costa, Benilde F.O.; Faneca, Henrique (4E1F-D234-7CD6); Durães, Luísa, 2020. Materials Science and Engineering: C. 111124 - 111138. 115. 2020. http://dx.doi.org/10.1016/j.msec.2020.111124 . 10.1016/j.msec.2020.111124 . published Materials Science and Engineering: C
Silica-Based Gene Delivery Systems: From Design to Therapeutic Applications
Carvalho, Ana Maria; Cordeiro, Rosemeyre A.; Faneca, Henrique (4E1F-D234-7CD6), 2020. Pharmaceutics. 649 - 694. 7. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12070649 . 10.3390/pharmaceutics12070649 . published Pharmaceutics
Polymeric nanoengineered HBsAg DNA vaccine designed in combination with ß-glucan
Edna Soares; Rosemeyre Cordeiro; Henrique Faneca; Olga Borges, 2019. International Journal of Biological Macromolecules. 930 - 939. 122. 2019. https://doi.org/10.1016/j.ijbiomac.2018.11.024 . 10.1016/j.ijbiomac.2018.11.024 . published International Journal of Biological Macromolecules
Poly(ethylene glycol)-block-poly(2-aminoethyl methacrylate hydrochloride)-based polyplexes as serum-tolerant nanosystems for enhanced gene delivery
Daniela Santo; Patrícia V. Mendonça; Mafalda S. Lima; Rosemeyre A. Cordeiro; Luis Cabanas; Arménio Serra; Jorge F.J. Coelho; Faneca, Henrique (4E1F-D234-7CD6), 2019. Molecular Pharmaceutics. 2129 - 2141. 5. 16. 2019. https://doi.org/10.1021/acs.molpharmaceut.9b00101 . 10.1021/acs.molpharmaceut.9b00101 . published Molecular Pharmaceutics
Replacing di(2-ethylhexyl) terephthalate by di(2-ethylhexyl) 2,5-furandicarboxylate for PVC plasticization: synthesis, materials preparation and characterization
Marina Matos; Rosemeyre A. Cordeiro; Faneca, Henrique; Jorge Coelho; Armando Silvestre; Andreia Sousa, 2019. Materials. 14. 12. 2019. http://dx.doi.org/10.3390/ma12142336 . 10.3390/ma12142336 . published Materials
Poly(ß-amino ester)-based gene delivery systems: From discovery to therapeutic applications
Rosemeyre A. Cordeiro; Arménio Serra; Jorge F.J. Coelho; Faneca, Henrique (4E1F-D234-7CD6), 2019. Journal of Controlled Release. 155 - 187. 310. 2019. https://doi.org/10.1016/j.jconrel.2019.08.024 . 10.1016/j.jconrel.2019.08.024 . published Journal of Controlled Release
High transfection efficiency promoted by tailor-made cationic tri-block copolymer-based nanoparticles
Cordeiro, R.A.; Santo, D.; Farinha, D.; Serra, A.; Faneca, Henrique (4E1F-D234-7CD6); Coelho, J.F.J., 2017. Acta Biomaterialia. 113 - 123. 47. 2017. https://doi.org/10.1016/j.actbio.2016.10.015 . 10.1016/j.actbio.2016.10.015 . published Acta Biomaterialia
Combination of poly[(2-dimethylamino)ethyl methacrylate] and poly(ß-amino ester) results in a strong and synergistic transfection activity
Santo, D.; Cordeiro, R.A.; Sousa, A.; Serra, A.; Coelho, J.F.J.; Faneca, Henrique (4E1F-D234-7CD6), 2017. Biomacromolecules. 3331 - 3342. 10. 18. 2017. https://doi.org/10.1021/acs.biomac.7b00983 . 10.1021/acs.biomac.7b00983 . published Biomacromolecules
Managing pancreatic adenocarcinoma: A special focus in microRNA gene therapy
Passadouro, M.; Faneca, Henrique (4E1F-D234-7CD6), 2016. International Journal of Molecular Sciences. 5. 17. 2016. https://doi.org/10.3390/ijms17050718 . 10.3390/ijms17050718 . published International Journal of Molecular Sciences
Intranasal administration of novel chitosan nanoparticle/DNA complexes induces antibody response to hepatitis B surface antigen in mice
Lebre, F.; Borchard, G.; Faneca, Henrique (4E1F-D234-7CD6); Pedroso De Lima, M.C.; Borges, O., 2016. Molecular Pharmaceutics. 472 - 482. 2. 13. 2016. https://doi.org/10.1021/acs.molpharmaceut.5b00707 . 10.1021/acs.molpharmaceut.5b00707 . published Molecular Pharmaceutics
Novel cationic triblock copolymer of poly[2-(dimethylamino)ethyl methacrylate]-block-poly(ß-amino ester)-block-poly[2-(dimethylamino)ethyl methacrylate]: A promising non-viral gene delivery system
Cordeiro, R.A.; Farinha, D.; Rocha, N.; Serra, A.C.; Faneca, Henrique (4E1F-D234-7CD6); Coelho, J.F.J., 2015. Macromolecular Bioscience. 215 - 228. 2. 15. 2015. https://doi.org/10.1002/mabi.201400424 . 10.1002/mabi.201400424 . published Macromolecular Bioscience
Shutting down the furnace: preferential killing of cancer cells with mitochondrial-targeting molecules
Deus, C.M.; Santos, G.L.; Loureiro, R.; Vega-Naredo, I.; Faneca, H.; Oliveira, P.J., 2015. Current Medicinal Chemistry. 2438 - 2457. 20. 22. 2015. http://www.eurekaselect.com/128348/article . 10.2174/0929867322666150209155957 . published Current Medicinal Chemistry
MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer
Passadouro, M.; Pedroso de Lima, M.C.; Faneca, Henrique (4E1F-D234-7CD6), 2014. International Journal of Nanomedicine. 3203 - 3217. 1. 9. 2014. https://www.dovepress.com/microrna-modulation-combined-with-sunitinib-as-a-novel-therapeutic-str-peer-reviewed-article-IJN . 10.2147/IJN.S64456 . published International Journal of Nanomedicine
Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid
Magalhães, M.; Farinha, D.; Pedroso de Lima, M.C.; Faneca, Henrique (4E1F-D234-7CD6), 2014. International journal of nanomedicine. 4979 - 4989. 9. 2014. https://www.dovepress.com/increased-gene-delivery-efficiency-and-specificity-of-a-lipid-based-na-peer-reviewed-article-IJN . 10.2147/IJN.S69822 . published International journal of nanomedicine
3D printing of new biobased unsaturated polyesters by microstereo-thermallithography
Gonçalves, F.A.; Costa, C.S.; Fabela, I.G.; Farinha, D.; Faneca, H.; Simões, P.N.; Serra, A.C.; Bártolo, P.J.; Coelho, J.F., 2014. Biofabrication. 3. 6. 2014. https://iopscience.iop.org/article/10.1088/1758-5082/6/3/035024 . 10.1088/1758-5082/6/3/035024 . published Biofabrication
Specific and efficient gene delivery mediated by an asialofetuin-associated nanosystem
Farinha, D.; Pedroso De Lima, M.C.; Faneca, Henrique (4E1F-D234-7CD6), 2014. International Journal of Pharmaceutics. 366 - 374. 1-2. 473. 2014. https://doi.org/10.1016/j.ijpharm.2014.07.019 . 10.1016/j.ijpharm.2014.07.019 . published International Journal of Pharmaceutics
Silica nanoparticles for bimodal MRI-optical imaging by grafting Gd3+ and Eu3+/Tb3+ complexes
Pinho, S.L.C.; Faneca, H.; Geraldes, C.F.G.C.; Rocha, J.; Carlos, L.D.; Delville, M.-H., 2012. European Journal of Inorganic Chemistry. 2828 - 2837. 16. 2012. https://doi.org/10.1002/ejic.201101110 . 10.1002/ejic.201101110 . published European Journal of Inorganic Chemistry
Isolation of head and neck squamous carcinoma cancer stem-like cells in a syngeneic mouse model and analysis of hypoxia effect
Duarte, S.; Loubat, A.; Momier, D.; Topi, M.; Faneca, H.; Pedroso De Lima, M.C.; Carle, G.F.; Pierrefite-Carle, V., 2012. Oncology Reports. 1057 - 1062. 3. 28. 2012. https://doi.org/10.3892/or.2012.1904 . 10.3892/or.2012.1904 . published Oncology Reports
Suicide gene therapy in cancer: Where do we stand now?
Duarte, S.; Carle, G.; Faneca, H.; Lima, M.C.P.D.; Pierrefite-Carle, V., 2012. Cancer Letters. 160 - 170. 2. 324. 2012. https://doi.org/10.1016/j.canlet.2012.05.023 . 10.1016/j.canlet.2012.05.023 . published Cancer Letters
Lanthanide-DTPA grafted silica nanoparticles as bimodal-imaging contrast agents
Pinho, S.L.C.; Faneca, H.; Geraldes, C.F.G.C.; Delville, M.-H.; Carlos, L.D.; Rocha, J., 2012. Biomaterials. 925 - 935. 3. 33. 2012. https://doi.org/10.1016/j.biomaterials.2011.09.086 . 10.1016/j.biomaterials.2011.09.086 . published Biomaterials
Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo
Duarte, S.; Faneca, H.; Lima, M.C.P.D., 2012. International Journal of Pharmaceutics. 365 - 377. 2. 423. 2012. hhttps://doi.org/10.1016/j.ijpharm.2011.12.035 . 10.1016/j.ijpharm.2011.12.035 . published International Journal of Pharmaceutics
Gemini surfactant dimethylene-1,2-bis(tetradecyldimethylammonium bromide)-based gene vectors: A biophysical approach to transfection efficiency
Ana M Cardoso; Faneca, Henrique; João Almeida; Alberto Pais; Eduardo Marques; Maria Pedroso Lima; Amália Jurado, 2011. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2011. http://dx.doi.org/10.1016/j.bbamem.2010.09.026 . 10.1016/j.bbamem.2010.09.026 . published Biochimica et Biophysica Acta (BBA) - Biomembranes
In situ forming chitosan hydrogels prepared via ionic/covalent co-cross-linking
Moura, M.J.; Faneca, H.; Lima, M.P.; Gil, M.H.; Figueiredo, M.M., 2011. Biomacromolecules. 3275 - 3284. 9. 12. 2011. https://doi.org/10.1021/bm200731x . 10.1021/bm200731x . published Biomacromolecules
Dicationic alkylammonium bromide gemini surfactants. membrane perturbation and skin irritation
Almeida, J.A.S.; Faneca, H.; Carvalho, R.A.; Marques, E.F.; Pais, A.A.C.C., 2011. PLoS ONE. 11. 6. 2011. https://doi.org/10.1371/journal.pone.0026965 . 10.1371/journal.pone.0026965 . published PLoS ONE
Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: effects on transfection efficiency and physicochemical properties
Lundberg, D.; Faneca, H.; Pedroso De Lima, M.C.; Miguel, M.D.G.; Lindman, B., 2011. Molecular Membrane Biology. 42 - 53. 1. 28. 2011. https://doi.org/10.3109/09687688.2010.508879 . 10.3109/09687688.2010.508879 . published Molecular Membrane Biology
Non-covalent association of folate to lipoplexes: a promising strategy to improve gene delivery in the presence of serum
Duarte, S.; Faneca, H.; Pedroso De Lima, M.C., 2011. Journal of Controlled Release. 264 - 272. 3. 149. 2011. https://doi.org/10.1016/j.jconrel.2010.10.032 . 10.1016/j.jconrel.2010.10.032 . published Journal of Controlled Release
Study of the antidiabetic capacity of the VO(dmpp)2 complex
Passadouro, M.; Metelo, A.M.; Melão, A.S.; Pedro, J.R.; Faneca, H.; Carvalho, E.; Castro, M.M.C.A., 2010. Journal of Inorganic Biochemistry. 987 - 992. 9. 104. 2010. https://doi.org/10.1016/j.jinorgbio.2010.05.004 . 10.1016/j.jinorgbio.2010.05.004 . published Journal of Inorganic Biochemistry
Interaction of proteinase inhibitors with phospholipid vesicles is modulated by pH
Silva-Lucca, R.A.; Faneca, H.M.S.; de Lima, M.C.P.; De Caroli, F.P.; Assis, M.L.; Sampaio, M.U.; Oliva, M.L.V., 2010. International Journal of Biological Macromolecules. 551 - 557. 4. 47. 2010. https://doi.org/10.1016/j.ijbiomac.2010.07.011 . 10.1016/j.ijbiomac.2010.07.011 . published International Journal of Biological Macromolecules
Vanadium compounds as therapeutic agents: some chemical and biochemical studies
Faneca, H.; Figueiredo, V.A.; Tomaz, I.; Gonçalves, G.; Avecilla, F.; Pedroso de Lima, M.C.; Geraldes, C.F.G.C.; Pessoa, J.C.; Castro, M.M.C.A., 2009. Journal of Inorganic Biochemistry. 601 - 608. 4. 103. 2009. https://doi.org/10.1016/j.jinorgbio.2008.11.004 . 10.1016/j.jinorgbio.2008.11.004 . published Journal of Inorganic Biochemistry
Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response
Neves, S.; Faneca, H.; Bertin, S.; Konopka, K.; Düzgünes, N.; Pierrefite-Carle, V.; Simões, S.; Pedroso De Lima, M.C., 2009. Cancer Gene Therapy. 91 - 101. 1. 16. 2009. hhttps://doi.org/10.1038/cgt.2008.60 . 10.1038/cgt.2008.60 . published Cancer Gene Therapy
Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomes
Faneca, H.; Faustino, A.; Pedroso de Lima, M.C., 2008. Journal of Controlled Release. 175 - 184. 2. 126. 2008. https://doi.org/10.1016/j.jconrel.2007.12.005 . 10.1016/j.jconrel.2007.12.005 . published Journal of Controlled Release
S413-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA
Sara Trabulo; Miguel Mano; Faneca, Henrique; Ana L Cardoso; Sónia Duarte; Ana Henriques; Artur Paiva; et al, 2008. The Journal of Gene Medicine. 1210 - 1222. 11. 10. 2008. https://doi.org/10.1002/jgm.1247 . 10.1002/jgm.1247 . published The Journal of Gene Medicine
Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system
Faneca, H.; Cabrita, A.S.; Simões, S.; Pedroso de Lima, M.C., 2007. Biochimica et Biophysica Acta - Biomembranes. 1093 - 1102. 5. 1768. 2007. https://doi.org/10.1016/j.bbamem.2006.12.017 . 10.1016/j.bbamem.2006.12.017 . published Biochimica et Biophysica Acta - Biomembranes
Cationic liposomes for gene delivery
Simões, S.; Filipe, A.; Faneca, H.; Mano, M.; Penacho, N.; Düzgünes, N.; de Lima, M.P., 2005. Expert Opinion on Drug Delivery. 237 - 254. 2. 2. 2005. https://doi.org/10.1517/17425247.2.2.237 . 10.1517/17425247.2.2.237 . published Expert Opinion on Drug Delivery
Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum
Faneca, H.; Simões, S.; Pedroso de Lima, M.C., 2004. Journal of Gene Medicine. 681 - 692. 6. 6. 2004. https://doi.org/10.1002/jgm.550 . 10.1002/jgm.550 . published Journal of Gene Medicine
Protein-associated lipoplexes: Novel strategies to enhance gene delivery mediated by lipid-based particles
Simões, S.; Fonseca, C.; Faneca, H.; Düzgünes, N.; Pedroso de Lima, M.C., 2002. S.T.P. Pharma Sciences. 339 - 344. 6. 12. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036855226&partnerID=MN8TOARS . published S.T.P. Pharma Sciences
Evaluation of lipid-based reagents to mediate intracellular gene delivery
Faneca, H.; Simões, S.; Pedroso de Lima, M.C., 2002. Biochimica et Biophysica Acta - Biomembranes. 23 - 33. SUPPL.. 1567. 2002. https://doi.org/10.1016/S0005-2736(02)00545-X . 10.1016/S0005-2736(02)00545-X . published Biochimica et Biophysica Acta - Biomembranes
Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications
Pedroso De Lima, M.C.; Simões, S.; Pires, P.; Faneca, H.; Düzgünes, N., 2001. Advanced Drug Delivery Reviews. 277 - 294. 2-3. 47. 2001. https://doi.org/10.1016/S0169-409X(01)00110-7 . 10.1016/S0169-409X(01)00110-7 . published Advanced Drug Delivery Reviews
5 51 out of 51 Publications
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