Cell Signaling and Metabolism in Disease

1,2-Dihydroxy-<i>9H</i>-Xanthen-9-One, a Multifunctional Nature-Inspired Active Ingredient

Ana Jesus; Sara F. Vieira; Brites, G; Mylène Carrascal; Helena Ferreira; Nuno M. Neves; Honorina Cidade; et al, 2024. Cosmetics. 2024. https://www.mdpi.com/2079-9284/11/6/215 . 10.3390/cosmetics11060215 . Cosmetics

Biological and phytochemical variation with pre- and post-harvest conditions for the Acanthus mollis L. leaf

Matos, Patrícia; Paranhos, António; Oliveiros, Bárbara; Cruz, Maria Teresa; Batista, Maria Teresa; Figueirinha, Artur, 2024. Industrial Crops and Products. 211. 2024. http://dx.doi.org/10.1016/j.indcrop.2024.118221 . 10.1016/j.indcrop.2024.118221 . Industrial Crops and Products

Effect of bioactive extracts from Eucalyptus globulus leaves in experimental models of Alzheimer’s disease

Moreira, Patrícia; Macedo, Jéssica; Matos, Patrícia; Bicker, Joana; Fortuna, Ana; Figueirinha, Artur; Salgueiro, Lígia; et al, 2024. Biomedicine &amp; Pharmacotherapy. 181. 2024. http://dx.doi.org/10.1016/j.biopha.2024.117652 . 10.1016/j.biopha.2024.117652 . published Biomedicine &amp; Pharmacotherapy

Unlocking the Bioactive Potential and Exploring Novel Applications for Portuguese Endemic Santolina impressa

Jorge M. Alves-Silva; Sónia Pedreiro; Mónica Zuzarte; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2024. Plants. 2024. https://doi.org/10.3390/plants13141943 . 10.3390/plants13141943 . Plants

Exploring the immunomodulatory properties of glucan particles in human primary cells

Panão Costa, João; Jesus, Sandra; Colaço, Mariana; Lebre, Filipa; Mateus, Daniela; Sebastião, Ana Isabel; Cruz, Maria Teresa; Alfaro-Moreno, Ernesto; Borges, Olga, 2024. International Journal of Pharmaceutics. 123996. 655. 2024. https://www.sciencedirect.com/science/article/pii/S0378517324002308?via%3Dihub . published International Journal of Pharmaceutics

The link between alterations in circadian rhythms and lipid metabolism in bipolar disorder: the lipid droplets hypothesis

Pereira, Ana Catarina; Serrano-Cuñarro, Laura; Cruz, Maria Teresa; Cavadas, Cláudia; Pereira, Cláudia Maria Fragão, 2024. Brazilian Journal of Psychiatry. 2024. https://doi.org/10.47626/1516-4446-2024-3670 . 10.47626/1516-4446-2024-3670 . Brazilian Journal of Psychiatry

Mannose and Lactobionic Acid in Nasal Vaccination: Enhancing Antigen Delivery via C-Type Lectin Receptors

Mariana Colaço; Maria T. Cruz; Luís Pereira de Almeida; Olga Borges, 2024. Pharmaceutics. 2024. https://doi.org/10.3390/pharmaceutics16101308 . 10.3390/pharmaceutics16101308 . Pharmaceutics

Mapping the lipidome in mitochondria-associated membranes (MAMs) in an in vitro model of Alzheimer's disease

Fernandes, Tânia; Melo, Tânia; Conde, Tiago; Neves, Bruna; Domingues, Pedro; Resende, Rosa; Pereira, Cláudia F.; Moreira, Paula I.; Domingues, Maria Rosário, 2024. Journal of Neurochemistry. 2024. http://dx.doi.org/10.1111/jnc.16072 . 10.1111/jnc.16072 . Journal of Neurochemistry

Protective effects of 2,4-dinitrophenol in okadaic acid-induced cellular model of Alzheimer's disease

Cardoso, Susana; Carvalho, Cristina; Correia, Sónia C.; Moreira, Paula I., 2024. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 6. 1870. 2024. http://dx.doi.org/10.1016/j.bbadis.2024.167222 . 10.1016/j.bbadis.2024.167222 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Effect of bioactive extracts from Eucalyptus globulus leaves in experimental models of Alzheimer’s disease

Moreira, Patrícia; Macedo, Jéssica; Matos, Patrícia; Bicker, Joana; Fortuna, Ana; Figueirinha, Artur; Salgueiro, Lígia; et al, 2024. Biomedicine &amp; Pharmacotherapy. 181. 2024. https://doi.org/10.1016/j.biopha.2024.117652 . 10.1016/j.biopha.2024.117652 . Biomedicine &amp; Pharmacotherapy

BACE1 Inhibitors for Alzheimer’s Disease: Current Challenges and Future Perspectives

Coimbra, Judite R.M.; Resende, Rosa; Custódio, José B.A.; Salvador, Jorge A.R.; Santos, Armanda E., 2024. Journal of Alzheimer's Disease. S53 - S78. s1. 101. 2024. http://dx.doi.org/10.3233/jad-240146 . 10.3233/jad-240146 . Journal of Alzheimer's Disease

Targeting Alzheimer's disease hallmarks with the Nrf2 activator Isoeugenol.

Ana Silva; Sónia Silva; Jéssica Macedo; Patrícia Moreira; Diana Baptista; Joana Bicker; Ana Fortuna; et al, 2024. 2024. https://doi.org/10.32388/LUXM7W . submitted

An integrated green process for the extraction of triterpenic acids from Eucalyptus globulus leaves after hydrodistillation

Cátia S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Alexandre Gaspar; Carlos Pascoal Neto; Paula C. R. O. Pinto; et al, 2023. RSC Sustainability. 2023. https://doi.org/10.1039/D3SU00076A . 10.1039/D3SU00076A . RSC Sustainability

A Hydrophilic Sulfated Resveratrol Derivative for Topical Application: Sensitization and Anti-Allergic Potential

Ana Jesus; Ana I. Sebastião; Gonçalo Brites; Marta Correia-da-Silva; Honorina Cidade; Maria T. Cruz; Emília Sousa; Isabel F. Almeida, 2023. Molecules. 2023. https://doi.org/10.3390/molecules28073158 . 10.3390/molecules28073158 . Molecules

How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies

Ana Torres; Liliana Rego; Márcia S. Martins; Marta S. Ferreira; Maria T. Cruz; Emília Sousa; Isabel F. Almeida, 2023. Pharmaceuticals. 2023. https://doi.org/10.3390/ph16040573 . 10.3390/ph16040573 . Pharmaceuticals

Polysaccharide-Based Carriers for Pulmonary Insulin Delivery: The Potential of Coffee as an Unconventional Source

Sara A. Valente; Guido R. Lopes; Isabel Ferreira; Miguel F. Galrinho; Margarida Almeida; Paula Ferreira; Maria T. Cruz; Manuel A. Coimbra; Cláudia P. Passos, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15041213 . 10.3390/pharmaceutics15041213 . Pharmaceutics

Effect of Thymbra capitata (L.) Cav. on Inflammation, Senescence and Cell Migration

Jorge M. Alves-Silva; Sónia Pedreiro; Carlos Cavaleiro; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2023. Nutrients. 2023. https://doi.org/10.3390/nu15081930 . 10.3390/nu15081930 . Nutrients

Comparative Studies on the Photoreactivity, Efficacy, and Safety of Depigmenting Agents

Sandra Mota; Gonçalo P. Rosa; Maria Carmo Barreto; Jorge Garrido; Emília Sousa; Maria T. Cruz; Isabel F. Almeida; Clara Quintas, 2023. Pharmaceuticals. 2023. https://doi.org/10.3390/ph17010055 . 10.3390/ph17010055 . Pharmaceuticals

Artificial Dendritic Cells: A New Era of Promising Antitumor Immunotherapy

Daniela Mateus; Ana I. Sebastião; Manuela F. Frasco; Mylène A. Carrascal; Amílcar Falcão; Célia M. Gomes; Bruno Neves; Maria G. F. Sales; Maria T. Cruz, 2023. Small. 2023. https://doi.org/10.1002/smll.202303940 . 10.1002/smll.202303940 . Small

An integrated green process for the extraction of triterpenic acids from Eucalyptus globulus leaves after hydrodistillation

Cátia S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Alexandre Gaspar; Carlos Pascoal Neto; Paula C. R. O. Pinto; et al, 2023. RSC Sustainability. 2023. https://doi.org/10.1039/D3SU00076A . 10.1039/D3SU00076A . RSC Sustainability

Lipidome of extracellular vesicles from Giardia lamblia

Clarissa Perez Faria; Maria de Fátima Matos Almeida Henriques de Macedo; Barbara Ferreira; Ágata Lourenço; Inês Guerra; Tânia Melo; Pedro Domingues; et al, 2023. PLOS ONE. 2023. https://doi.org/10.1371/journal.pone.0291292 . 10.1371/journal.pone.0291292 . PLOS ONE

Development of an in chemico high-throughput screening method for the identification of skin sensitization potential

Isabel Ferreira; Gonçalo Brites; Ana Silva; Francisco Caramelo; Bárbara Oliveiros; Bruno Miguel Neves; Maria Teresa Cruz, 2023. Archives of Toxicology. 2023. https://doi.org/10.1007/s00204-023-03550-z . 10.1007/s00204-023-03550-z . Archives of Toxicology

Current Advances in Mitochondrial Targeted Interventions in Alzheimer's Disease

Tiago Sousa; Paula I. Moreira; Susana Cardoso, 2023. Biomedicines. 2023. https://doi.org/10.3390/biomedicines11092331 . 10.3390/biomedicines11092331 . Biomedicines

Therapeutic potential of glutaminyl cyclases: Current status and emerging trends

Coimbra, Judite R.M.; Moreira, Paula I.; Santos, Armanda E.; Salvador, Jorge A.R., 2023. Drug Discovery Today. 2023. http://dx.doi.org/10.1016/j.drudis.2023.103644 . 10.1016/j.drudis.2023.103644 . Drug Discovery Today

Metabolic defects shared by Alzheimer's disease and diabetes: A focus on mitochondria

Cristina Carvalho; Paula I. Moreira, 2023. Current Opinion in Neurobiology. 2023. https://doi.org/10.1016/j.conb.2023.102694 . 10.1016/j.conb.2023.102694 . Current Opinion in Neurobiology

A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases

Tânia Fernandes; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2023. Biology. 2023. https://doi.org/10.3390/biology12030414 . 10.3390/biology12030414 . Biology

Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells

B.J. Conti; K.B. Santiago; E.O. Cardoso; F.L. Conte; M.A. Golim; M.T. Cruz; J.M. Sforcin, 2023. Brazilian Journal of Medical and Biological Research. 2023. https://doi.org/10.1590/1414-431x2023e12659 . 10.1590/1414-431x2023e12659 . Brazilian Journal of Medical and Biological Research

CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell Activation and Th1 Polarization

Ana Isabel Sebastião; Daniela Mateus; Mylène A. Carrascal; Cátia Sousa; Luísa Cortes; Martin F. Bachmann; Anália do Carmo; et al, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15030825 . 10.3390/pharmaceutics15030825 . Pharmaceutics

A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases

Tânia Fernandes; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2023. Biology. 2023. https://doi.org/10.3390/biology12030414 . 10.3390/biology12030414 . Biology

Exploiting the Integrated Valorization of Eucalyptus globulus Leaves: Chemical Composition and Biological Potential of the Lipophilic Fraction before and after Hydrodistillation

Cátia. S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2023. International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24076226 . 10.3390/ijms24076226 . International Journal of Molecular Sciences

Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease

Batista, Ana; Guimarães, Pedro; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Serranho, Pedro; Bernardes, Rui, 2023. Frontiers in Aging Neuroscience. 15. 2023. http://dx.doi.org/10.3389/fnagi.2023.1161847 . 10.3389/fnagi.2023.1161847 . Frontiers in Aging Neuroscience

Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina rosmarinifolia L. Essential Oil from Portugal

Jorge M. Alves-Silva; Maria José Gonçalves; Ana Silva; Carlos Cavaleiro; Maria Teresa Cruz; Lígia Salgueiro, 2023. Antibiotics. 2023. https://doi.org/10.3390/antibiotics12010179 . 10.3390/antibiotics12010179 . Antibiotics

Redox signalling and proteostasis in neurodegeneration: In vivo effects of the mitochondria-targeted antioxidant MitoQ in Huntington's disease mice

Pinho, Brígida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M.A., 2023. Free Radical Biology and Medicine. S5 - S6. 198. 2023. http://dx.doi.org/10.1016/j.freeradbiomed.2022.12.030 . 10.1016/j.freeradbiomed.2022.12.030 . Free Radical Biology and Medicine

Retinal imaging in animal models: Searching for biomarkers of neurodegeneration

Batista, Ana; Guimarães, Pedro; Serranho, Pedro; Nunes, Ana; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; et al, 2023. Frontiers in Ophthalmology. 3. 2023. http://dx.doi.org/10.3389/fopht.2023.1156605 . 10.3389/fopht.2023.1156605 . Frontiers in Ophthalmology

Exploring the Traditional Uses of <i>Thymbra capitata</i> Infusion in Algarve (Portugal): Anti-Inflammatory, Wound Healing, and Anti-Aging

Jorge Miguel Alves-Silva; Sónia Pedreiro; Cruz MT; Salgueiro L.; Artur Figueirinha, 2023. Pharmaceuticals. 2023. https://www.mdpi.com/1424-8247/16/9/1202 . 10.3390/ph16091202 . Pharmaceuticals

The Effect of Curcumin-Loaded Glucan Nanoparticles on Immune Cells: Size as a Critical Quality Attribute

Mariana Colaço; Tiago Roquito; João Panão Costa; Maria Teresa Cruz; Olga Borges, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15020623 . 10.3390/pharmaceutics15020623 . Pharmaceutics

Exploiting the Integrated Valorization of Eucalyptus globulus Leaves: Chemical Composition and Biological Potential of the Lipophilic Fraction before and after Hydrodistillation

Cátia. S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2023. International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24076226 . 10.3390/ijms24076226 . International Journal of Molecular Sciences

Antioxidants in Sunscreens: Which and What For?

Ana Jesus; Sandra Mota; Ana Torres; Maria T. Cruz; Emília Sousa; Isabel F. Almeida; Honorina Cidade, 2023. Antioxidants. 2023. https://doi.org/10.3390/antiox12010138 . 10.3390/antiox12010138 . Antioxidants

Therapeutic potential of glutaminyl cyclases: Current status and emerging trends

Coimbra, Judite R.M.; Moreira, Paula I.; Santos, Armanda E.; Salvador, Jorge A.R., 2023. Drug Discovery Today. 10. 28. 2023. http://dx.doi.org/10.1016/j.drudis.2023.103644 . 10.1016/j.drudis.2023.103644 . Drug Discovery Today

Effect of Ferulago lutea (Poir.) Grande Essential Oil on Molecular Hallmarks of Skin Aging

Jorge M. Alves-Silva; Patrícia Moreira; Carlos Cavaleiro; Cláudia Pereira; Maria Teresa Cruz; Lígia Salgueiro, 2023. Plants. 2023. https://doi.org/10.3390/plants12213741 . 10.3390/plants12213741 . Plants

Advances in the Phytochemical Characterisation and Bioactivities of Salvia aurea L. Essential Oil

Jorge Miguel Alves-Silva; Delia Maccioni; Emma Cocco; Maria José Gonçalves; Silvia Porcedda; Alessandra Piras; Maria Teresa Cruz; Lígia Salgueiro; Andrea Maxia, 2023. Plants. 2023. https://doi.org/10.3390/plants12061247 . 10.3390/plants12061247 . Plants

Unveiling the Chemical Composition and Biological Properties of Salvia cacaliifolia Benth. Essential Oil

Jorge M. Alves-Silva; Emma Cocco; Alessandra Piras; Maria José Gonçalves; Ana Silva; Danilo Falconieri; Silvia Porcedda; et al, 2023. Plants. 2023. https://doi.org/10.3390/plants12020359 . 10.3390/plants12020359 . Plants

Impact of Gastrointestinal Digestion on the Anti-Inflammatory Properties of Phlorotannins from Himanthalia elongata

Marcelo D. Catarino; Ana Rita Circuncisão; Bruno Neves; Catarina Marçal; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso, 2022. Antioxidants. 2022. https://doi.org/10.3390/antiox11081518 . 10.3390/antiox11081518 . Antioxidants

Forest Biomass as a Promising Source of Bioactive Essential Oil and Phenolic Compounds for Alzheimer’s Disease Therapy

Patrícia Moreira; Patrícia Matos; Artur Figueirinha; Lígia Salgueiro; Maria Teresa Batista; Pedro Costa Branco; Maria Teresa Cruz; Cláudia Fragão Pereira, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23158812 . 10.3390/ijms23158812 . International Journal of Molecular Sciences

Lavandula viridis L´Hér. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade

Zuzarte, Monica; Francisco, Vera; Neves, Bruno; Liberal, Joana; Cavaleiro, Carlos; Canhoto, Jorge; Salgueiro, Lígia; Cruz, Maria Teresa; Salgueiro, Ligia, 2022. Frontiers in Pharmacology. 12. 2022. http://dx.doi.org/10.3389/fphar.2021.695911 . 10.3389/fphar.2021.695911 . Frontiers in Pharmacology

Protective role of Portuguese natural mineral waters on skin aging: in vitro evaluation of anti-senescence and anti-oxidant properties.

Vaz CV; Oliveira AS; Silva A; Cortes L; Correia S; Ferreira R; Breitenfeld L; et al, 2022. International journal of biometeorology. 2022. http://europepmc.org/abstract/med/35994120 . 10.1007/s00484-022-02345-8 . International journal of biometeorology

UV Filters: Challenges and Prospects

Ana Jesus; Emília Sousa; Maria T. Cruz; Honorina Cidade; José M. Sousa Lobo; Isabel F. Almeida, 2022. Pharmaceuticals. 263 - 263. 3. 15. 2022. https://doi.org/10.3390/ph15030263 . 10.3390/ph15030263 . Pharmaceuticals

Development of colorimetric cellulose-based test-strip for the rapid detection of antibodies against SARS-CoV2 virus.

Cruz MT, 2022. Cellulose (London, England). 2022. https://europepmc.org/articles/PMC9483301 . 10.1007/s10570-022-04808-y . Cellulose (London, England)

Chemical Composition and Effect against Skin Alterations of Bioactive Extracts Obtained by the Hydrodistillation of <i>Eucalyptus globulus</i> Leaves

Patrícia Moreira; Fábio J. Sousa; Patrícia Matos; Brites, G; Maria José Gonçalves; Carlos Cavaleiro; Artur Figueirinha; et al, 2022. Pharmaceutics. 2022. https://www.mdpi.com/1999-4923/14/3/561 . 10.3390/pharmaceutics14030561 . Pharmaceutics

WWOX inhibition by Zfra1-31 restores mitochondrial homeostasis and viability of neuronal cells exposed to high glucose

Cristina Carvalho; Sónia C. Correia; Raquel Seiça; Paula I. Moreira, 2022. Cellular and Molecular Life Sciences. 2022. https://doi.org/10.1007/s00018-022-04508-7 . 10.1007/s00018-022-04508-7 . Cellular and Molecular Life Sciences

ER-Mitochondria contacts modulate ROS-mediated signaling and oxidative stress in brain disorders: the key role of Sigma-1 receptor.

Resende, Rosa; Fernandes, Tânia; Pereira, Ana Catarina; Marques, Ana Patrícia; Pereira, Cláudia Fragão, 2022. Antioxidants & Redox Signaling. 2022. http://dx.doi.org/10.1089/ars.2020.8231 . 10.1089/ars.2020.8231 . published Antioxidants & Redox Signaling

Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer’s disease: Past, present and future

2022. Ageing Research Reviews. 101612 - 101612. 77. 2022. http://dx.doi.org/10.1016/j.arr.2022.101612 . 10.1016/j.arr.2022.101612 . Ageing Research Reviews

Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes

2022. Phytomedicine Plus. 100231 - 100231. 2. 2. 2022. http://dx.doi.org/10.1016/j.phyplu.2022.100231 . 10.1016/j.phyplu.2022.100231 . Phytomedicine Plus

Stage-independent biomarkers for Alzheimer’s disease from the living retina: an animal study

Ferreira, Hugo; Serranho, Pedro; Guimarães, Pedro; Trindade, Rita; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui, 2022. Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-18113-y . 10.1038/s41598-022-18113-y . Scientific Reports

Longitudinal OCT texture analysis to assess the retinal changes in the triple-transgenic mouse model of Alzheimer's disease

Bernardes, Rui; Ghalati, Maryam; Ferreira, Hugo; Martins, João; Guimarães, Pedro; Moreira, Paula; Ambrósio, António; Castelo-Branco, Miguel; Serranho, Pedro, 2022. Acta Ophthalmologica. S275. 100. 2022. http://dx.doi.org/10.1111/j.1755-3768.2022.0173 . 10.1111/j.1755-3768.2022.0173 . Acta Ophthalmologica

Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1a/SIRT3 Pathway

Antónia Diniz; Marco G. Alves; Emanuel Candeias; Ana I. Duarte; Paula I. Moreira; Branca M. Silva; Pedro F. Oliveira; Luís Rato, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23168912 . 10.3390/ijms23168912 . International Journal of Molecular Sciences

Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease

Guimarães, Pedro; Serranho, Pedro; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui, 2022. Frontiers in Aging Neuroscience. 14. 2022. http://dx.doi.org/10.3389/fnagi.2022.832195 . 10.3389/fnagi.2022.832195 . Frontiers in Aging Neuroscience

Hypoxic preconditioning averts sporadic Alzheimer’s disease-like phenotype in rats: a focus on mitochondria

Correia, Sónia C.; Alves, Marco G.; Oliveira, Pedro F.; Casadesus, Gemma; LaManna, Joseph; Perry, George; Moreira, Paula I., 2022. Antioxidants & Redox Signaling. 2022. http://dx.doi.org/10.1089/ars.2019.8007 . 10.1089/ars.2019.8007 . Antioxidants & Redox Signaling

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

Pereira, Ana Catarina; De Pascale, Jessica; Resende, Rosa; Cardoso, Susana; Ferreira, Isabel; Neves, Bruno Miguel; Carrascal, Mylène A.; et al, 2022. Cellular and Molecular Life Sciences. 4. 79. 2022. http://dx.doi.org/10.1007/s00018-022-04211-7 . 10.1007/s00018-022-04211-7 . Cellular and Molecular Life Sciences

Forest Biomass as a Promising Source of Bioactive Essential Oil and Phenolic Compounds for Alzheimer’s Disease Therapy

Patrícia Moreira; Patrícia Matos; Artur Figueirinha; Lígia Salgueiro; Maria Teresa Batista; Pedro Costa Branco; Maria Teresa Cruz; Cláudia Fragão Pereira, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23158812 . 10.3390/ijms23158812 . International Journal of Molecular Sciences

Up-to-Date Overview of the Use of Natural Ingredients in Sunscreens

Diana I. S. P. Resende; Ana Jesus; José M. Sousa Lobo; Emília Sousa; Maria T. Cruz; Honorina Cidade; Isabel F. Almeida, 2022. Pharmaceuticals. 372 - 372. 3. 15. 2022. https://doi.org/10.3390/ph15030372 . 10.3390/ph15030372 . Pharmaceuticals

Synergistic hypoglycemic and hypolipidemic effects of ¿-3 and ¿-6 fatty acids from Indian flax and sesame seed oils in streptozotocin-induced diabetic rats

Sunil Chikkalakshmipura Gurumallu; Tareq N. AlRamadneh; Halugudde Nagaraja Sarjan; Ashwini Bhaskar; Cláudia Maria Fragão Pereira; Rajesha Javaraiah, 2022. Phytomedicine Plus. 2022. https://doi.org/10.1016/j.phyplu.2022.100284 . 10.1016/j.phyplu.2022.100284 . Phytomedicine Plus

Bioactive Bacterial Nanocellulose Membranes Enriched with Eucalyptus globulus Labill. Leaves Aqueous Extract for Anti-Aging Skin Care Applications

Almeida, Tânia; Moreira, Patrícia; Sousa, Fábio J.; Pereira, Cláudia; Silvestre, Armando J. D.; Vilela, Carla; Freire, Carmen S. R., 2022. Materials. 5. 15. 2022. http://dx.doi.org/10.3390/ma15051982 . 10.3390/ma15051982 . published Materials

Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes

Conte, Fernanda Lopes; Pereira, Ana Catarina; Brites, Gonçalo; Ferreira, Isabel; Silva, Ana Cristina; Sebastião, Ana Isabel; Matos, Patrícia; et al, 2022. Phytomedicine Plus. 2. 2. 2022. http://dx.doi.org/10.1016/j.phyplu.2022.100231 . 10.1016/j.phyplu.2022.100231 . Phytomedicine Plus

Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes

Pereira, Ana Catarina; Madeira, Nuno; Morais, Sofia; Macedo, António; Cruz, Maria Teresa; Pereira, Cláudia M. F., 2022. Cells. 3. 11. 2022. http://dx.doi.org/10.3390/cells11030433 . 10.3390/cells11030433 . accepted Cells

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

2022. Cellular and Molecular Life Sciences. 4. 79. 2022. http://dx.doi.org/10.1007/s00018-022-04211-7 . 10.1007/s00018-022-04211-7 . Cellular and Molecular Life Sciences

Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes

Ana Catarina Pereira; Nuno Madeira; Sofia Morais; António Macedo; Maria Teresa Cruz; Cláudia M. F. Pereira, 2022. Cells. 433 - 433. 3. 11. 2022. https://doi.org/10.3390/cells11030433 . 10.3390/cells11030433 . Cells

The Anti-Inflammatory Response of Lavandula luisieri and Lavandula pedunculata Essential Oils

Monica Zuzarte; Cátia Sousa; Carlos Cavaleiro; Maria Teresa Cruz; Lígia Salgueiro, 2022. Plants. 2022. https://doi.org/10.3390/plants11030370 . 10.3390/plants11030370 . Plants

Recent Trends on UV filters

Ana Jesus; Inês Augusto; Joana Duarte; Emília Sousa; Honorina Cidade; Maria T. Cruz; José M. Sousa Lobo; Isabel F. Almeida, 2022. Applied Sciences. 2022. https://doi.org/10.3390/app122312003 . 10.3390/app122312003 . Applied Sciences

Chemical Composition and Effect against Skin Alterations of Bioactive Extracts Obtained by the Hydrodistillation of <i>Eucalyptus globulus</i> Leaves

Patrícia Moreira; Fábio J. Sousa; Patrícia Matos; Brites, G; Maria José Gonçalves; Carlos Cavaleiro; Artur Figueirinha; et al, 2022. Pharmaceutics. 2022. https://www.mdpi.com/1999-4923/14/3/561 . 10.3390/pharmaceutics14030561 . Pharmaceutics

Improvement of Glycaemia and Endothelial Function by a New Low-Dose Curcuminoid in an Animal Model of Type 2 Diabetes

Sara Oliveira; Tamaeh Monteiro-Alfredo; Rita Henriques; Carlos Fontes Ribeiro; Raquel Seiça; Teresa Cruz; Célia Cabral; et al, 2022. International Journal of Molecular Sciences. 5652 - 5652. 10. 23. 2022. https://doi.org/10.3390/ijms23105652 . 10.3390/ijms23105652 . International Journal of Molecular Sciences

In-Depth Analysis of the Impact of Different Serum-Free Media on the Production of Clinical Grade Dendritic Cells for Cancer Immunotherapy

Calmeiro, J.; Mendes, L.; Duarte, I.F.; Leitão, C.; Tavares, A.R.; Ferreira, D.A.; Gomes, C.; et al, 2021. Frontiers in Immunology. 11. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85101266995&partnerID=MN8TOARS . 10.3389/fimmu.2020.593363 . Frontiers in Immunology

Physical and biochemical alterations in endoplasmic reticulum-mitochondria contacts in an Alzheimer's disease in vitro model

Fernandes, Tânia; Resende, Rosa; Domingues, Maria R.; Paula I. Moreira; Pereira, Cláudia Fragão, 2021. European Journal of Clinical Investigation. S1. 51. 2021. http://dx.doi.org/10.1111/eci.13567 . published European Journal of Clinical Investigation

Insulin-Induced Recurrent Hypoglycemia Up-Regulates Glucose Metabolism in the Brain Cortex of Chemically Induced Diabetic Rats

Susana Cardoso; Paula I. Moreira, 2021. International Journal of Molecular Sciences. 2021. https://doi.org/10.3390/ijms222413470 . 10.3390/ijms222413470 . International Journal of Molecular Sciences

WWOX: A New Therapeutic Target In Type 2 Diabetes-Associated Neurodegeneration

Carvalho, Cristina; Moreira, Paula I., 2021. Metabolism. 116. 2021. http://dx.doi.org/10.1016/j.metabol.2020.154616 . 10.1016/j.metabol.2020.154616 . Metabolism

Oxygen Sensing and Signaling in Alzheimer's Disease: A Breathtaking Story!

Sónia C. Correia; Paula I. Moreira, 2021. Cellular and Molecular Neurobiology. 2021. https://doi.org/10.1007/s10571-021-01148-6 . 10.1007/s10571-021-01148-6 . Cellular and Molecular Neurobiology

Chemical characterization and bioactive potential of Artemisia campestris L. subsp. maritima (DC) Arcang. essential oil and hydrodistillation residual water

Rocha, M.I.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Pereira, C.; Moreira, P.; Salgueiro, L.; et al, 2021. Journal of Ethnopharmacology. 276. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105307700&partnerID=MN8TOARS . 10.1016/j.jep.2021.114146 . Journal of Ethnopharmacology

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer’s Disease

Fernandes, Tânia; Resende, Rosa; Silva, Diana F.; Marques, Ana P.; Santos, Armanda E.; Cardoso, Sandra M.; Domingues, M. Rosário; Moreira, Paula I.; Pereira, Cláudia F., 2021. Biomedicines. 8. 9. 2021. http://dx.doi.org/10.3390/biomedicines9080881 . 10.3390/biomedicines9080881 . Biomedicines

Inflammation in Bipolar Disorder (BD): Identification of new therapeutic targets

Pereira, Ana Catarina; Oliveira, Joana; Silva, Sónia; Madeira, Nuno; Pereira, Cláudia M.F.; Cruz, Maria T., 2021. Pharmacological Research. 163. 2021. http://dx.doi.org/10.1016/j.phrs.2020.105325 . 10.1016/j.phrs.2020.105325 . published Pharmacological Research

Therapies for Alzheimer’s disease: a metabolic perspective

Domingues, Raquel; Pereira, Claúdia; Cruz, Maria Teresa; Silva, Ana, 2021. Molecular Genetics and Metabolism. 21. S1096-71. 2021. http://dx.doi.org/10.1016/j.ymgme.2021.01.011 . 10.1016/j.ymgme.2021.01.011 . published Molecular Genetics and Metabolism

Mitochondrial Alterations in Fibroblasts of Early Stage Bipolar Disorder Patients

Ana P. Marques; Rosa Resende; Diana F. Silva; Mariana Batista; Daniela Pereira; Brigite Wildenberg; Sofia Morais; et al, 2021. Biomedicines. 2021. https://www.mdpi.com/2227-9059/9/5/522 . 10.3390/biomedicines9050522 . Biomedicines

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimers Disease

Fernandes, Tânia; Resende, Rosa; Silva, Diana F.; Marques, Ana P.; Santos, Armanda E.; Cardoso, Sandra M.; Domingues, M. Rosário; Moreira, Paula I.; Pereira, Cláudia F., 2021. Biomedicines. 8. 9. 2021. http://dx.doi.org/10.3390/biomedicines9080881 . 10.3390/biomedicines9080881 . published Biomedicines

Chemical characterization and bioactive potential of Artemisia campestris L. subsp. maritima (DC) Arcang. essential oil and hydrodistillation residual water

Rocha, Maria Inês; Gonçalves, Maria José; Cavaleiro, Carlos; Cruz, Maria Teresa; Pereira, Cláudia; Moreira, Patrícia; Salgueiro, Lígia; Figueirinha, Artur, 2021. Journal of Ethnopharmacology. 276. 2021. http://dx.doi.org/10.1016/j.jep.2021.114146 . 10.1016/j.jep.2021.114146 . published Journal of Ethnopharmacology

IGF1R Deficiency Modulates Brain Signaling Pathways and Disturbs Mitochondria and Redox Homeostasis

Susana Cardoso; Icíar López; Sergio Piñeiro-Hermida; José Pichel; Paula Moreira, 2021. Biomedicines. 158 - 158. 2. 9. 2021. https://doi.org/10.3390/biomedicines9020158 . 10.3390/biomedicines9020158 . Biomedicines

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Pinheiro, T.; Cardoso, A.R.; Sousa, C.E.A.; Marques, A.C.; Tavares, A.P.M.; Matos, A.M.; Cruz, M.T.; et al, 2021. ACS Omega. 29268 - 29290. 44. 6. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85118899020&partnerID=MN8TOARS . 10.1021/acsomega.1c04012 . ACS Omega

Therapies for Alzheimer's disease: a metabolic perspective

Domingues, R.; Pereira, C.; Cruz, M.T.; Silva, A.; Domingues, Raquel; Pereira, Claudia; Cruz, Maria Teresa; Silva, Ana, 2021. Molecular Genetics and Metabolism. 162 - 172. 3. 132. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100399064&partnerID=MN8TOARS . 10.1016/j.ymgme.2021.01.011 . Molecular Genetics and Metabolism

Chemical composition and biological activity of essential oil of Teucrium scordium L. subsp. scordioides (Schreb.) Arcang. (Lamiaceae) from Sardinia Island (Italy)

Piras, A.; Maccioni, A.; Falconieri, D.; Porcedda, S.; Gonçalves, M.J.; Alves-Silva, J.M.; Silva, A.; et al, 2021. Natural Product Research. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85121839185&partnerID=MN8TOARS . 10.1080/14786419.2021.2018432 . Natural Product Research

Antifungal and Anti-Inflammatory Potential of Bupleurum rigidum subsp. paniculatum (Brot.) H.Wolff Essential Oil

Mónica Zuzarte; Pedro M. P. Correia; Jorge M. Alves-Silva; Maria J. Gonçalves; Carlos Cavaleiro; Teresa Cruz; Lígia Salgueiro, 2021. Antibiotics. 592 - 592. 5. 10. 2021. https://doi.org/10.3390/antibiotics10050592 . 10.3390/antibiotics10050592 . Antibiotics

Anti-Inflammatory Activity of Calendula officinalis L. Flower Extract

Diva Silva; Marta Salvador Ferreira; José Manuel Sousa-Lobo; Maria Teresa Cruz; Isabel Filipa Almeida, 2021. Cosmetics. 2021. https://doi.org/10.3390/cosmetics8020031 . 10.3390/cosmetics8020031 . Cosmetics

Antitumor Activity of Fucus vesiculosus-Derived Phlorotannins through Activation of Apoptotic Signals in Gastric and Colorectal Tumor Cell Lines

Marcelo D. Catarino; Iva Fernandes; Hélder Oliveira; Mylene Carrascal; Rita Ferreira; Artur M. S. Silva; Maria Teresa Cruz; Nuno Mateus; Susana M. Cardoso, 2021. International Journal of Molecular Sciences. 7604 - 7604. 14. 22. 2021. https://doi.org/10.3390/ijms22147604 . 10.3390/ijms22147604 . International Journal of Molecular Sciences

Pharmacological combination of nivolumab with dendritic cell vaccines in cancer immunotherapy: An overview

Calmeiro, J.; Carrascal, M.A.; Tavares, A.R.; Ferreira, D.A.; Gomes, C.; Cruz, M.T.; Falcão, A.; et al, 2021. Pharmacological Research. 164. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85099552475&partnerID=MN8TOARS . 10.1016/j.phrs.2020.105309 . Pharmacological Research

Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's Disease

Sónia C. Correia; Nuno J. Machado; Marco G. Alves; Pedro F. Oliveira; Paula I. Moreira, 2021. International Journal of Molecular Sciences. 461 - 461. 1. 22. 2021. https://doi.org/10.3390/ijms22010461 . 10.3390/ijms22010461 . International Journal of Molecular Sciences

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; et al, 2021. Autophagy. 1 - 382. 1. 17. 2021. http://dx.doi.org/10.1080/15548627.2020.1797280 . 10.1080/15548627.2020.1797280 . Autophagy

Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's disease

Ferreira, Hugo; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Serranho, Pedro; Bernardes, Rui, 2021. Aging. 2021. http://dx.doi.org/10.18632/aging.202916 . 10.18632/aging.202916 . Aging

Role of Coffee Caffeine and Chlorogenic Acids Adsorption to Polysaccharides with Impact on Brew Immunomodulation Effects

Cláudia P. Passos; Rita M. Costa; Sónia S. Ferreira; Guido R. Lopes; Maria T. Cruz; Manuel A. Coimbra, 2021. Foods. 2021. https://doi.org/10.3390/foods10020378 . 10.3390/foods10020378 . Foods

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer's Disease

Tânia Fernandes; Rosa Resende; Diana F. Silva; Ana P. Marques; Armanda E. Santos; Sandra M. Cardoso; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2021. Biomedicines. 881 - 881. 8. 9. 2021. https://doi.org/10.3390/biomedicines9080881 . 10.3390/biomedicines9080881 . Biomedicines

Propolis from southeastern Brazil produced by Apis mellifera affects innate immunity by modulating cell marker expression, cytokine production and intracellular pathways in human monocytes

Conte, Fernanda Lopes; Santiago, Karina Basso; Conti, Bruno Jose; Cardoso, Eliza de Oliveira; Garcia Oliveira, Lucas Pires; Feltran, Georgia da Silva; Zambuzzi, Willian Fernando; et al, 2021. Journal of Pharmacy and Pharmacology. 135 - 144. 2. 73. 2021. https://publons.com/publon/46053419/ . 10.1093/JPP/RGAA023 . Journal of Pharmacy and Pharmacology

Crosstalk between estrogen, dendritic cells, and SARS-CoV-2 infection

Mateus, Daniela; Sebastiao, Ana Isabel; Carrascal, Mylene A.; do Carmo, Analia; Matos, Ana Miguel; Cruz, Maria Teresa; Mateus, D.; et al, 2021. Reviews in Medical Virology. 2021. https://publons.com/publon/49453726/ . 10.1002/RMV.2290 . Reviews in Medical Virology

Exosomes as new therapeutic vectors for pancreatic cancer treatment

Oliveira, Constanca; Calmeiro, Joao; Carrascal, Mylene A.; Falcao, Amilcar; Gomes, Celia; Neves, Bruno Miguel; Cruz, Maria Teresa, 2021. European Journal of Pharmaceutics and Biopharmaceutics. 2021. https://publons.com/publon/39705379/ . 10.1016/J.EJPB.2021.02.002 . European Journal of Pharmaceutics and Biopharmaceutics

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

Calmeiro, João; Carrascal, Mylène A.; Tavares, Adriana Ramos; Ferreira, Daniel Alexandre; Gomes, Célia; Falcão, Amílcar; Cruz, Maria Teresa; et al, 2020. Pharmaceutics. 2. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12020158 . 10.3390/pharmaceutics12020158 . Pharmaceutics

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

Pinho, Brígida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M.A., 2020. Free Radical Biology and Medicine. 372 - 382. 146. 2020. http://dx.doi.org/10.1016/j.freeradbiomed.2019.11.021 . 10.1016/j.freeradbiomed.2019.11.021 . Free Radical Biology and Medicine

Liraglutide Protects Against Brain Amyloid-ß1-42 Accumulation in Female Mice with Early Alzheimer's Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

Ana I. Duarte; Emanuel Candeias; Inês N. Alves; Débora Mena; Daniela F. Silva; Nuno J. Machado; Elisa J. Campos; et al, 2020. International Journal of Molecular Sciences. 2020. https://doi.org/10.3390/ijms21051746 . 10.3390/ijms21051746 . International Journal of Molecular Sciences

Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do Mitochondria-Associated Membranes (MAMs) play a role?

R. Resende; T. Fernandes; A.C. Pereira; J. De Pascale; A.P. Marques; P. Oliveira; S. Morais; et al, 2020. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 165752 - 165752. 6. 1866. 2020. https://doi.org/10.1016/j.bbadis.2020.165752 . 10.1016/j.bbadis.2020.165752 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbata

Cátia S. D. Oliveira; Patrícia Moreira; Judite Resende; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2020. International Journal of Molecular Sciences. 1814 - 1830. 5. 21. 2020. https://doi.org/10.3390/ijms21051814 . 10.3390/ijms21051814 . International Journal of Molecular Sciences

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Silva, Ana; Pereira, Marta; Carrascal, Mylène A.; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia; Resende, Rosa; et al, 2020. International Journal of Molecular Sciences. 20. 21. 2020. http://dx.doi.org/10.3390/ijms21207791 . 10.3390/ijms21207791 . International Journal of Molecular Sciences

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Santos, Armanda, 2020. International Journal of Molecular Sciences. 2020. https://www.mdpi.com/1422-0067/21/20/7791 . 10.3390/ijms21207791 . International Journal of Molecular Sciences

Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do Mitochondria-Associated Membranes (MAMs) play a role?

Resende, R.; Fernandes, T.; Pereira, A.C.; De Pascale, J.; Marques, A.P.; Oliveira, P.; Morais, S.; et al, 2020. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 6. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2020.165752 . 10.1016/j.bbadis.2020.165752 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

New BACE1 chimeric peptide inhibitors selectively prevent AßPP-ß cleavage decreasing Aß production and accumulation in AD models

Santos, Armanda E, 2020. Journal of Alzheimers Disease. 2020. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad200381 . 10.3233/JAD-200381 . Journal of Alzheimers Disease

Anti-inflammatory potential of Portuguese thermal waters

Silva, A.; Oliveira, A. S.; Vaz, C. V.; Correia, S.; Ferreira, R.; Breitenfeld, L.; Martinez-de-Oliveira, J.; et al, 2020. Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-79394-9 . 10.1038/s41598-020-79394-9 . published Scientific Reports

Chemical composition of Crithmum maritimum L. essential oil and hydrodistillation residual water by GC-MS and HPLC-DAD-MS/MS, and their biological activities

Jorge M. Alves-Silva; Inês Guerra; Maria José Gonçalves; Carlos Cavaleiro; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2020. Industrial Crops and Products. 112329 - 112329. 149. 2020. https://doi.org/10.1016/j.indcrop.2020.112329 . 10.1016/j.indcrop.2020.112329 . Industrial Crops and Products

Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors

Coimbra, Judite R. M.; Baptista, Salete J.; Dinis, Teresa C. P.; Silva, Maria M. C.; Moreira, Paula I.; Santos, Armanda E.; Salvador, Jorge A. R., 2020. Biomolecules. 4. 10. 2020. http://dx.doi.org/10.3390/biom10040535 . 10.3390/biom10040535 . Biomolecules

Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer's disease

Ferreira, Hugo; Martins, João; Nunes, Ana; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António Francisco; Serranho, Pedro; Bernardes, Rui, 2020. Health and Technology. 1816 - 1821. 2020. http://dx.doi.org/10.1007/s12553-020-00413-w . 10.1007/s12553-020-00413-w . Health and Technology

PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

Quinn, Peter M. J.; Moreira, Paula I.; Ambrósio, António Francisco; Alves, C. Henrique, 2020. Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-01062-w . 10.1186/s40478-020-01062-w . published Acta Neuropathologica Communications

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Cunnane, Stephen C.; Trushina, Eugenia; Morland, Cecilie; Prigione, Alessandro; Casadesus, Gemma; Andrews, Zane B.; Beal, M. Flint; et al, 2020. Nature Reviews Drug Discovery. 2020. http://dx.doi.org/10.1038/s41573-020-0072-x . 10.1038/s41573-020-0072-x . Nature Reviews Drug Discovery

Associations between Trace Elements and Cognitive Decline: An Exploratory 5-Year Follow-Up Study of an Elderly Cohort

Bianca Gerardo; Marina Cabral Pinto; Joana Nogueira; Paula Pinto; Agostinho Almeida; Edgar Pinto; Paula Marinho-Reis; et al, 2020. International Journal of Environmental Research and Public Health. 2020. https://doi.org/10.3390/ijerph17176051 . 10.3390/ijerph17176051 . International Journal of Environmental Research and Public Health

Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors

Judite R. M. Coimbra; Salete J. Baptista; Teresa C. P. Dinis; Maria M. C. Silva; Paula I. Moreira; Armanda E. Santos; Jorge A. R. Salvador, 2020. Biomolecules. 535 - 535. 4. 10. 2020. https://doi.org/10.3390/biom10040535 . 10.3390/biom10040535 . Biomolecules

Characterization of the retina of the triple-transgenic mice model of Alzheimer's disease: onset and progression of the disease

Bernardes, Rui; Ferreira, Hugo; Martins, Joao; Moreira, Paula; Francisco Ambrosio, Antonio; Castelo-Branco, Miguel; Serranho, Pedro, 2020. Neurology. 2020. https://publons.com/wos-op/publon/40788837/ . Neurology

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AßPPß Cleavage Decreasing Amyloid-ß Production and Accumulation in Alzheimers Disease Models

Resende, Rosa; Ferreira-Marques, Marisa; Moreira, Patrícia; Coimbra, Judite R.M.; Baptista, Salete J.; Isidoro, Ciro; Salvador, Jorge A.R.; et al, 2020. Journal of Alzheimer's Disease. 1317 - 1337. 6. 70. 2020. http://dx.doi.org/10.3233/jad-200381 . 10.3233/jad-200381 . published Journal of Alzheimer's Disease

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; Martinez-de-Oliveira, José; et al, 2020. International Journal of Biometeorology. 1957 - 1968. 11. 64. 2020. http://dx.doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . published International Journal of Biometeorology

Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbata

Oliveira, Catia S. D.; Moreira, Patricia; Resende, Judite; Cruz, Maria T.; Pereira, Claudia M. F.; Silva, Artur M. S.; Santos, Sonia A. O.; et al, 2020. International Journal of Molecular Sciences. 5. 21. 2020. https://publons.com/publon/32969534/ . 10.3390/IJMS21051814 . International Journal of Molecular Sciences

Chemical characterization and bioactivity of the essential oil from Santolina insularis, a Sardinian endemism

Alves-Silva, J.M.; Piras, A.; Porcedda, S.; Falconieri, D.; Maxia, A.; Gonçalves, M.J.; Cruz, M.T.; Salgueiro, L., 2020. Natural Product Research. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85086880740&partnerID=MN8TOARS . 10.1080/14786419.2020.1774764 . Natural Product Research

Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-¿B Signaling Pathway

Marcelo D. Catarino; Ana Silva; Maria T. Cruz; Nuno Mateus; Artur M.S. Silva; Susana M. Cardoso, 2020. International Journal of Molecular Sciences. 2020. https://doi.org/10.3390/ijms21186897 . 10.3390/ijms21186897 . International Journal of Molecular Sciences

Crepis vesicaria L. subsp. taraxacifolia Leaves: Nutritional Profile, Phenolic Composition and Biological Properties

Sónia Pedreiro; Sandrine da Ressurreição; Maria Lopes; Maria Teresa Cruz; Teresa Batista; Artur Figueirinha; Fernando Ramos, 2020. International Journal of Environmental Research and Public Health. 2020. https://doi.org/10.3390/ijerph18010151 . 10.3390/ijerph18010151 . International Journal of Environmental Research and Public Health

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Ana Silva; Marta Pereira; Mylène Carrascal; Brites, G; Neves BM; Patrícia Moreira; Rosa Resende; et al, 2020. International Journal of Molecular Sciences. 2020. https://www.mdpi.com/1422-0067/21/20/7791 . 10.3390/ijms21207791 . International Journal of Molecular Sciences

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, A.S.; Vaz, C.V.; Silva, A.; Ferreira, S.S.; Correia, S.; Ferreira, R.; Breitenfeld, L.; et al, 2020. Environmental Geochemistry and Health. 2039 - 2057. 7. 42. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076109661&partnerID=MN8TOARS . 10.1007/s10653-019-00473-6 . Environmental Geochemistry and Health

NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify

Ana Isabel Sebastião; Isabel Ferreira; Gonçalo Brites; Ana Silva; Bruno Miguel Neves; Maria Teresa Cruz, 2020. Pharmaceutics. 867 - 867. 9. 12. 2020. https://doi.org/10.3390/pharmaceutics12090867 . 10.3390/pharmaceutics12090867 . Pharmaceutics

Giardia lamblia Decreases NF-kappa B p65(RelA) Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages

Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenco, Agata; Cruz, Maria Teresa; Martins, Joao D.; Silva, Ana; Pereira, Sonia; et al, 2020. Scientific Reports. 1. 10. 2020. https://publons.com/publon/932727/ . 10.1038/S41598-020-63231-0 . published Scientific Reports

Evaluating Skin Sensitization Via Soft and Hard Multivariate Modeling

Silva, F.A.L.S.; Brites, G.; Ferreira, I.; Silva, A.; Miguel Neves, B.; Costa Pereira, J.L.G.F.S.; Cruz, M.T., 2020. International Journal of Toxicology. 547 - 559. 6. 39. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85089197709&partnerID=MN8TOARS . 10.1177/1091581820944395 . International Journal of Toxicology

Calcium Signaling in Aging and Neurodegenerative Diseases 2019

Luísa Cortes; João Malva; Ana Cristina Rego; Cláudia F. Pereira, 2020. International Journal of Molecular Sciences. 1125 - 1125. 3. 21. 2020. https://doi.org/10.3390/ijms21031125 . 10.3390/ijms21031125 . International Journal of Molecular Sciences

Antifungal and anti-inflammatory potential of the endangered aromatic plant Thymus albicans

Roxo, Mariana; Zuzarte, Monica; Goncalves, Maria Jose; Alves-Silva, Jorge M.; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, Ligia; et al, 2020. Scientific Reports. 1. 10. 2020. https://publons.com/publon/36630873/ . 10.1038/S41598-020-75244-W . Scientific Reports

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Ana Sofia Oliveira; Cátia Vicente Vaz; Ana Silva; Sara Correia; Raquel Ferreira; Luiza Breitenfeld; José Martinez-de-Oliveira; et al, 2020. International Journal of Biometeorology. 2020. https://doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . International Journal of Biometeorology

Allergic contact dermatitis: From pathophysiology to development of new preventive strategies

Gonçalo Sousa Brites; Isabel Ferreira; Ana Isabel Sebastião; Ana Silva; Mylene Carrascal; Bruno Miguel Neves; Maria T. Cruz, 2020. Pharmacological Research. 105282 - 105282. 2020. https://doi.org/10.1016/j.phrs.2020.105282 . 10.1016/j.phrs.2020.105282 . Pharmacological Research

Inflammation in Bipolar Disorder (BD): Identification of New Therapeutic Targets

Ana Catarina Pereira; Joana Oliveira; Sónia Silva; Nuno Madeira; Cláudia MF Pereira; Maria T Cruz; Oliveira, Joana; et al, 2020. Pharmacological Research. 163. 2020. https://publons.com/publon/34012396/ . 10.1016/J.PHRS.2020.105325 . Pharmacological Research

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Ferreira, Sandra Saraiva; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; et al, 2019. Environmental Geochemistry and Health. 2019. http://dx.doi.org/10.1007/s10653-019-00473-6 . 10.1007/s10653-019-00473-6 . published Environmental Geochemistry and Health

A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

Chiquita, Samuel; Ribeiro, Mário; Castelhano, João; Oliveira, Francisco; Sereno, José; Batista, Marta; Abrunhosa, Antero; et al, 2019. Human Molecular Genetics. 2174 - 2188. 13. 28. 2019. http://dx.doi.org/10.1093/hmg/ddz045 . 10.1093/hmg/ddz045 . Human Molecular Genetics

Is Alzheimer’s disease an inflammasomopathy?

Pereira, Claudia F.; Santos, Armanda E.; Moreira, Paula I.; Pereira, Ana Catarina; Sousa, Fabio J.; Cardoso, Sandra M.; Cruz, M. Teresa, 2019. Ageing Research Reviews. 56. 2019. http://dx.doi.org/10.1016/j.arr.2019.100966 . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

Apple pomace extract as a sustainable food ingredient

Fernandes, P.A.R.; Ferreira, S.S.; Bastos, R.; Ferreira, I.; Cruz, M.T.; Pinto, A.; Coelho, E.; et al, 2019. Antioxidants. 6. 8. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069685332&partnerID=MN8TOARS . 10.3390/antiox8060189 . Antioxidants

Retinal thickness of the triple-transgenic mice model of Alzheimer's disease at the age of one month

Bernardes, Rui; Ferreira, Hugo; Martins, João; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António F.; Serranho, Pedro, 2019. Acta Ophthalmologica. S263. 97. 2019. http://dx.doi.org/10.1111/j.1755-3768.2019.5467 . 10.1111/j.1755-3768.2019.5467 . Acta Ophthalmologica

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

Paiva, Rafael Almeida; Martins-Marques, Tania; Jesus, Katia; Ribeiro-Rodrigues, Teresa; Zuzarte, Monica; Silva, Ana; Reis, Liliana; et al, 2019. Journal of Cellular and Molecular Medicine. 2019. https://publons.com/publon/18866715/ . 10.1111/JCMM.14014 . Journal of Cellular and Molecular Medicine

Development of a curcumin derivative with hypoglycemic properties: Impact on oxidative stress and endothelial function in type 2 diabetes

Oliveira, Sara; Monteiro, Tamaeh; Henriques, Rita; Aspercada, Luis; Ribeiro, Carlos Fontes; Seica, Raquel; Cruz, Teresa; et al, 2019. European Journal of Clinical Investigation. 2019. https://publons.com/publon/30741253/ . European Journal of Clinical Investigation

Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer's disease?

Rodrigues-Neves, Ana Catarina; Carecho, Rafael; Baptista, Filipa; Moreira, Paula; Ambrósio, António, 2019. Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/conf.fncel.2019.01.00020 . 10.3389/conf.fncel.2019.01.00020 . Frontiers in Cellular Neuroscience

Biomaterial-based platforms for in situ dendritic cell programming and their use in antitumor immunotherapy

Calmeiro, Joao; Carrascal, Mylene; Gomes, Celia; Falcao, Amilcar; Cruz, Maria Teresa; Neves, Bruno Miguel; Calmeiro, J.; et al, 2019. Journal for ImmunoTherapy of Cancer. 1. 7. 2019. https://publons.com/publon/22830157/ . 10.1186/S40425-019-0716-8 . Journal for ImmunoTherapy of Cancer

The role of endoplasmic reticulum stress in the innate immune system in bipolar disorder

Pereira, A. C.; Ferreira, I.; Neves, B.; Moura, D.; Morais, S.; Madeira, N.; Macedo, A.; Cruz, M. T.; Pereira, C., 2019. European Psychiatry. 2019. https://publons.com/publon/30841015/ . European Psychiatry

Development of a novel dendritic cell-based immunotherapy targeting cancer stem cells

Calmeiro, Joao; Carrascal, Mylene; Mendes, Luis; Duarte, Iola F.; Gomes, Celia; Serra, Joao; Falcao, Amilcar; Cruz, Maria Teresa; Neves, Bruno Miguel, 2019. Journal of Clinical Oncology. 2019. https://publons.com/publon/21604203/ . 10.1200/JCO.2019.37.15_SUPPL.E14009 . Journal of Clinical Oncology

Unveiling the antifungal potential of two iberian thyme essential oils: Effect on C. albicans germ tube and preformed biofilms

Alves, M.; Gonçalves, M.J.; Zuzarte, M.; Alves-Silva, J.M.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L.; et al, 2019. Frontiers in Pharmacology. MAY. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068820197&partnerID=MN8TOARS . 10.3389/fphar.2019.00446 . Frontiers in Pharmacology

Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies

Pinho, Tiffany S.; Correia, Sónia C.; Perry, George; Ambrósio, António Francisco; Moreira, Paula I., 2019. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2048 - 2059. 8. 1865. 2019. http://dx.doi.org/10.1016/j.bbadis.2018.10.037 . 10.1016/j.bbadis.2018.10.037 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Células Estaminais Pluripotentes Induzidas no Tratamento da Doença de Alzheimer

Cruz, Maria Teresa; Marinheira, Joana; Silva, Sónia; Marinheira, Joana Filipa Rodrigues, 2019. 2019. http://www.actafarmaceuticaportuguesa.com/index.php/afp/article/view/190 .

Diabesity and brain disturbances: A metabolic perspective

Susana Cardoso; Paula I. Moreira, 2019. Molecular Aspects of Medicine. 71 - 79. 66. 2019. https://doi.org/10.1016/j.mam.2018.10.002 . 10.1016/j.mam.2018.10.002 . Molecular Aspects of Medicine

An overview of glutaminyl cyclase inhibitors for Alzheimer's disease

Coimbra, J.R.M.; Sobral, P.J.M.; Santos, A.E.; Moreira, P.I.; Salvador, J.A.R., 2019. Future Medicinal Chemistry. 3179 - 3194. 24. 11. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076529321&partnerID=MN8TOARS . 10.4155/fmc-2019-0163 . Future Medicinal Chemistry

Is Alzheimer's disease an inflammasomopathy?

Pereira, C.F.; Santos, A.E.; Moreira, P.I.; Pereira, A.C.; Sousa, F.J.; Cardoso, S.M.; Cruz, M.T., 2019. Ageing Research Reviews. 56. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072809334&partnerID=MN8TOARS . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

The cellular stress response in the immune system

Pereira, Claudia; Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Morais, Sofia; Madeira, Nuno; Santos, Vitor; Macedo, Antonio; Cruz, Maria Teresa, 2019. European Journal of Clinical Investigation. 2019. https://publons.com/publon/26807090/ . European Journal of Clinical Investigation

A defined approach for skin sensitization potency integrating in silico, in chemico and in vitro cell data

Ferreira, I.; Brites, G.; Silva, A.; Cruz, M. T.; Neves, B. M., 2019. Toxicology Letters. 2019. https://publons.com/publon/26807094/ . Toxicology Letters

Oxidized phosphatidylserine mitigates LPS-triggered macrophage inflammatory status through modulation of JNK and NF-kB signaling cascades

Maciel, Elisabete; Neves, Bruno M.; Martins, Joao; Colombo, Simone; Cruz, Maria Teresa; Domingues, Pedro; Domingues, M. Rosario M.; Cruz, Maria Teresa, 2019. Cellular Signalling. 2019. https://publons.com/publon/20224929/ . 10.1016/J.CELLSIG.2019.04.015 . Cellular Signalling

The Eighth ECS Workshop on “Calcium Signaling in Aging and Neurodegenerative Diseases”

Jan Parys; C Pereira; Carlos Villalobos, 2019. International Journal of Molecular Sciences. 2019. https://www.mdpi.com/1422-0067/20/24/6263 . 10.3390/ijms20246263 . International Journal of Molecular Sciences

Is Alzheimer's disease an inflammasomopathy?

Pereira, C.F.; Santos, A.E.; Moreira, P.I.; Pereira, A.C.; Sousa, F.J.; Cardoso, S.M.; Cruz, M.T.; et al, 2019. Ageing Research Reviews. 56. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072809334&partnerID=MN8TOARS . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer's Disease: Critical Aspects to Unravel

Chiquita, Samuel; Rodrigues-Neves, Ana C.; Baptista, Filipa I.; Carecho, Rafael; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António F., 2019. Molecular Neurobiology. 5416 - 5435. 8. 56. 2019. http://dx.doi.org/10.1007/s12035-018-1461-6 . 10.1007/s12035-018-1461-6 . Molecular Neurobiology

Chimeric Antigenic Receptor (CAR) T Cells: A New Immunotherapeutic Strategy

Cruz, Maria Teresa; Mateus, Daniela Marques; Borges, Olga, 2019. 2019. http://revista.farmacoterapia.pt/index.php/rpf/article/view/222 . 10.25756/rpf.v11i2-3.219 .

Unveiling the bioactive potential of the essential oil of a Portuguese endemism, Santolina impressa

Alves-Silva, J.M.; Zuzarte, M.; Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Salgueiro, L.; Alves-Silva, J. M.; Goncalves, M. J.; Cruz, M. T., 2019. Journal of Ethnopharmacology. 244. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070094953&partnerID=MN8TOARS . 10.1016/j.jep.2019.112120 . Journal of Ethnopharmacology

Nanostructuring lipid carriers using Ridolfia segetum (L.) Moris essential oil

Miranda, M.; Cruz, M.T.; Vitorino, C.; Cabral, C.; Miranda, Margarida; Cruz, Maria Teresa; Vitorino, Carla; Cabral, Celia, 2019. Materials Science and Engineering C. 103. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85066465144&partnerID=MN8TOARS . 10.1016/j.msec.2019.109804 . Materials Science and Engineering C

Post-translational modifications in brain health and disease

Correia, Sónia C.; Carvalho, Cristina; Cardoso, Susana; Moreira, Paula I., 2019. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1947 - 1948. 8. 1865. 2019. http://dx.doi.org/10.1016/j.bbadis.2019.05.006 . 10.1016/j.bbadis.2019.05.006 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

An overview of glutaminyl cyclase inhibitors for Alzheimer’s disease

Coimbra, Judite RM; Sobral, Pedro JM; Santos, Armanda E; Moreira, Paula I; Salvador, Jorge AR, 2019. Future Medicinal Chemistry. 3179 - 3194. 24. 11. 2019. http://dx.doi.org/10.4155/fmc-2019-0163 . 10.4155/fmc-2019-0163 . Future Medicinal Chemistry

Links between Cognitive Status and Trace Element Levels in Hair for an Environmentally Exposed Population: A Case Study in the Surroundings of the Estarreja Industrial Area

Cabral Pinto, Marina M. S.; Marinho-Reis, Paula; Almeida, Agostinho; Pinto, Edgar; Neves, Orquídia; Inácio, Manuela; Gerardo, Bianca; et al, 2019. International Journal of Environmental Research and Public Health. 22. 16. 2019. http://dx.doi.org/10.3390/ijerph16224560 . 10.3390/ijerph16224560 . International Journal of Environmental Research and Public Health

Is Alzheimer's disease an inflammasomopathy?

Pereira, Claudia F.; Santos, Armanda E.; Moreira, Paula I.; Pereira, Ana Catarina; Sousa, Fabio J.; Cardoso, Sandra M.; Cruz, M. Teresa, 2019. Ageing Research Reviews. 56. 2019. http://dx.doi.org/10.1016/j.arr.2019.100966 . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo study

Chiquita, Samuel; Campos, Elisa J.; Castelhano, João; Ribeiro, Mário; Sereno, José; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António Francisco, 2019. Alzheimer's Research & Therapy. 1. 11. 2019. http://dx.doi.org/10.1186/s13195-019-0542-8 . 10.1186/s13195-019-0542-8 . Alzheimer's Research & Therapy

Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer's Disease.

Moreira, PI, 2019. Advances in experimental medicine and biology. 2019. https://doi.org/10.1007/978-981-13-3540-2_9 . 10.1007/978-981-13-3540-2_9 . Advances in experimental medicine and biology

Editorial: The Physiology of Inflammation—The Final Common Pathway to Disease

Mendes, A.F.; Cruz, M.T.; Gualillo, O.; Ferreira Mendes, Alexandrina; Teresa Cruz, Maria; Gualillo, Oreste; Mendes, Alexandrina Ferreira; Cruz, Maria Teresa, 2018. Frontiers in Physiology. 9. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070433771&partnerID=MN8TOARS . 10.3389/fphys.2018.01741 . Frontiers in Physiology

New Insights into the Anti-Inflammatory and Antioxidant Properties of Nitrated Phospholipids

Melo, Tania; Marques, Sara S.; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, Pedro; Segundo, Marcela A.; Marques Domingues, Maria Rosario; et al, 2018. Lipids. 117 - 131. 1. 53. 2018. https://publons.com/publon/3423064/ . 10.1002/LIPD.12007 . Lipids

Polyphenolic characterization and bioactivity of an Oxalis pes-caprae L. leaf extract.

Santos, Armanda, 2018. Natural Product Research. 2018. https://www.ncbi.nlm.nih.gov/pubmed/28627294 . 10.1080/14786419.2017.1335728 . Natural Product Research

O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease

Tiffany S. Pinho; Diogo M. Verde; Sónia C. Correia; Susana M. Cardoso; Paula I. Moreira, 2018. Ageing Research Reviews. 32 - 41. 46. 2018. https://doi.org/10.1016/j.arr.2018.05.003 . 10.1016/j.arr.2018.05.003 . Ageing Research Reviews

Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease

Duarte, A.I.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I., 2018. Neuropharmacology. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044268663&partnerID=MN8TOARS . 10.1016/j.neuropharm.2018.01.044 . Neuropharmacology

Sweet Mitochondria: A Shortcut to Alzheimer's Disease

Moreira, P.I., 2018. Journal of Alzheimer's Disease. 1391 - 1401. 3. 62. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044360897&partnerID=MN8TOARS . 10.3233/JAD-170931 . Journal of Alzheimer's Disease

Exosomes as adjuvants for the recombinant hepatitis B antigen: First report

Sandra Jesus; Edna Soares; Maria Teresa Cruz; Olga Borges; Jesus, Sandra; Soares, Edna; Cruz, Maria Teresa; Borges, Olga, 2018. European Journal of Pharmaceutics and Biopharmaceutics. 1 - 11. 133. 2018. https://doi.org/10.1016/j.ejpb.2018.09.029 . 10.1016/j.ejpb.2018.09.029 . European Journal of Pharmaceutics and Biopharmaceutics

New insights on the anti-inflammatory potential and safety profile of Thymus carnosus and Thymus camphoratus essential oils and their main compounds

Zuzarte, M.; Alves-Silva, J.M.; Alves, M.; Cavaleiro, C.; Salgueiro, L.; Cruz, M.T.; Zuzarte, Monica; et al, 2018. Journal of Ethnopharmacology. 10 - 17. 225. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049324707&partnerID=MN8TOARS . 10.1016/j.jep.2018.06.025 . Journal of Ethnopharmacology

Polyphenolic characterisation and bioactivity of an Oxalis pes-caprae L. leaf extract

Gaspar, M.C.; Fonseca, D.A.; Antunes, M.J.; Frigerio, C.; Gomes, N.G.M.; Vieira, M.; Santos, A.E.; et al, 2018. Natural Product Research. 732 - 738. 6. 32. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021073702&partnerID=MN8TOARS . 10.1080/14786419.2017.1335728 . Natural Product Research

Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1

Ferreira, Isabel; Silva, Ana; Martins, Joao Demetrio; Neves, Bruno Miguel; Cruz, Maria Teresa; Cruz, Maria Teresa, 2018. Redox Biology. 2018. https://publons.com/publon/16980300/ . 10.1016/J.REDOX.2018.02.002 . Redox Biology

Impact of different GMP media in the production of dendritic cells for next-generation cancer immunotherapy: Functional and metabolic characterization

Calmeiro, J.; Carrascal, M.; Gomes, C.; Falcao, A.; Serra, J.; Cruz, M. T.; Neves, B., 2018. Annals of Oncology. 2018. https://publons.com/publon/26807098/ . Annals of Oncology

Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment

Coimbra, Judite R. M.; Marques, Daniela F. F.; Baptista, Salete J.; Pereira, Cláudia M. F.; Moreira, Paula I.; Dinis, Teresa C. P.; Santos, Armanda E.; Salvador, Jorge A. R., 2018. Frontiers in Chemistry. 6. 2018. http://dx.doi.org/10.3389/fchem.2018.00178 . 10.3389/fchem.2018.00178 . published Frontiers in Chemistry

Acanthus mollis L. leaves as source of anti-inflammatory and antioxidant phytoconstituents

Cruz, Maria Teresa, 2018. 2018. http://dx.doi.org/10.1080/14786419.2018.1437438 . 10.1080/14786419.2018.1437438 .

Bioactivity of Acanthus mollis – Contribution of benzoxazinoids and phenylpropanoids

Cruz, Maria Teresa, 2018. 2018. http://dx.doi.org/10.1016/j.jep.2018.09.013 . 10.1016/j.jep.2018.09.013 .

Highlights in BACE1 inhibitors for Alzheimer's disease treatment

Coimbra, J.R.M.; Marques, D.F.F.; Baptista, S.J.; Pereira, C.M.F.; Moreira, P.I.; Dinis, T.C.P.; Santos, A.E.; Salvador, J.A.R., 2018. Frontiers in Chemistry. MAY. 6. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048225310&partnerID=MN8TOARS . 10.3389/fchem.2018.00178 . Frontiers in Chemistry

Fingernail Trace Element Content in Environmentally Exposed Individuals and Its Influence on Their Cognitive Status in Ageing

Cabral Pinto, Marina M. S.; Marinho-Reis, A. Paula; Almeida, Agostinho; Freitas, Sandra; Simões, Mário R.; Diniz, M. Luísa; Pinto, Edgar; et al, 2018. Exposure and Health. 181 - 194. 3. 11. 2018. http://dx.doi.org/10.1007/s12403-018-0274-1 . 10.1007/s12403-018-0274-1 . Exposure and Health

The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy

Marques-Aleixo, I.; Santos-Alves, E.; Oliveira, P.J.; Moreira, P.I.; Magalhães, J.; Ascensão, A., 2018. Biochimica et Biophysica Acta - Reviews on Cancer. 189 - 199. 2. 1869. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041805508&partnerID=MN8TOARS . 10.1016/j.bbcan.2018.01.002 . Biochimica et Biophysica Acta - Reviews on Cancer

Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's Disease

Ana I. Duarte; Marie Sjögren; Maria S. Santos; Catarina R. Oliveira; Paula I. Moreira; Maria Björkqvist, 2018. Scientific Reports. 1. 8. 2018. https://doi.org/10.1038/s41598-018-27121-w . 10.1038/s41598-018-27121-w . Scientific Reports

Beneficial effects of white wine polyphenols-enriched diet on Alzheimer's disease-like pathology

Mendes, D.; Oliveira, M.M.; Moreira, P.I.; Coutinho, J.; Nunes, F.M.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Videira, R.A., 2018. Journal of Nutritional Biochemistry. 165 - 177. 55. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043298266&partnerID=MN8TOARS . 10.1016/j.jnutbio.2018.02.001 . Journal of Nutritional Biochemistry

The activation of the G protein-coupled estrogen receptor (GPER) inhibits the proliferation of mouse melanoma K1735-M2 cells

Mariana P.C. Ribeiro; Armanda E. Santos; José B.A. Custódio, 2017. Chemico-Biological Interactions. 176 - 184. 277. 2017. https://doi.org/10.1016/j.cbi.2017.09.017 . 10.1016/j.cbi.2017.09.017 . Chemico-Biological Interactions

Chemical Composition of Laurencia obtusa Extract and Isolation of a New C-15-Acetogenin

Esselin, Helene; Sutour, Sylvain; Liberal, Joana; Cruz, Maria Teresa; Salgueiro, Ligia; Siegler, Benjamin; Freuze, Ingrid; et al, 2017. Molecules. 5. 22. 2017. https://publons.com/publon/10621865/ . 10.3390/MOLECULES22050779 . Molecules

Contact dermatitis: in pursuit of sensitizer’s molecular targets through proteomics

Guedes, S.; Neves, B.; Vitorino, R.; Domingues, R.; Cruz, M.T.; Domingues, P.; Guedes, Sofia; et al, 2017. Archives of Toxicology. 811 - 825. 2. 91. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964645560&partnerID=MN8TOARS . 10.1007/s00204-016-1714-y . Archives of Toxicology

Ionotropic glutamate receptor antagonists and cancer therapy: time to think out of the box?

Ribeiro, M.P.C.; Custódio, J.B.A.; Santos, A.E., 2017. Cancer Chemotherapy and Pharmacology. 219 - 225. 2. 79. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84984821839&partnerID=MN8TOARS . 10.1007/s00280-016-3129-0 . Cancer Chemotherapy and Pharmacology

Assessment of safe bioactive doses of Foeniculum vulgare Mill. essential oil from Portugal

Cabral, C.; Miranda, M.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L., 2017. Natural Product Research. 2654 - 2659. 22. 31. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014579756&partnerID=MN8TOARS . 10.1080/14786419.2017.1292266 . Natural Product Research

When, where and how: mitochondrial multifaceted dysfunction in Alzheimer's disease

Oliveira, C. R.; Pereira, C.; Rego, A. C.; Moreira, P. I.; Cardoso, S., 2017. European Journal of Clinical Investigation. 24 - 25. 47. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000412099900035&KeyUID=WOS:000412099900035 . European Journal of Clinical Investigation

Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells

Placido, Ana I.; Pereira, Claudia M. F.; Correira, Sonia C.; Carvalho, Cristina; Oliveira, Catarina R.; Moreira, Paula I., 2017. Molecular Neurobiology. 154 - 168. 1. 54. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000392133900014&KeyUID=WOS:000392133900014 . 10.1007/s12035-015-9640-1 . Molecular Neurobiology

Inflammasome in dendritic cells immunobiology: Implications to diseases and therapeutic strategies

Ferreira, I.; Liberal, J.; Martins, J.D.; Silva, A.; Neves, B.M.; Cruz, M.T., 2017. Current Drug Targets. 1003 - 1018. 9. 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022193483&partnerID=MN8TOARS . 10.2174/1389450117666160921144830 . Current Drug Targets

Uncoupling Protein 2 Inhibition Exacerbates Glucose Fluctuation-Mediated Neuronal Effects

Cardoso, S.; Seiça, R.M.; Moreira, P.I., 2017. Neurotoxicity Research. 1 - 14. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028984223&partnerID=MN8TOARS . 10.1007/s12640-017-9805-y . Neurotoxicity Research

Mitochondria as a target for neuroprotection: implications for Alzheimer´s disease

Cardoso, S.; Seiça, R.M.; Moreira, P.I., 2017. Expert Review of Neurotherapeutics. 77 - 91. 1. 17. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85003782022&partnerID=MN8TOARS . 10.1080/14737175.2016.1205488 . Expert Review of Neurotherapeutics

Antioxidant and anti-inflammatory activities of: Geranium robertianum L. decoctions

Catarino, M.D.; Silva, A.M.S.; Cruz, M.T.; Cardoso, S.M.; Marcelo D. Catarino; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso, 2017. Food and Function. 3355 - 3365. 9. 8. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029740286&partnerID=MN8TOARS . 10.1039/c7fo00881c . Food and Function

Valorization of Lipids from Gracilaria sp through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity

da Costa, Elisabete; Melo, Tania; Moreira, Ana S. P.; Bernardo, Carina; Helguero, Luisa; Ferreira, Isabel; Cruz, Maria Teresa; et al, 2017. Marine Drugs. 3. 15. 2017. https://publons.com/publon/3423052/ . 10.3390/MD15030062 . Marine Drugs

Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

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The Flavone Luteolin Inhibits Liver X Receptor Activation

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BRAZILIAN PROPOLIS MODULATES CYTOKINE PRODUCTION BY LPS-ACTIVATED HUMAN MONOCYTES

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PROPOLIS ACTION IN CYTOKINE PRODUCTION BY RETINOIC ACID-STIMULATED HUMAN MONOCYTES

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Alzheimer's Disease: From Mitochondrial Perturbations to Mitochondrial Medicine

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Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells

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Ridolfia segetum (L.) Moris (Apiaceae) from Portugal: A source of safe antioxidant and anti-inflammatory essential oil

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Alzheimer's Disease-Related Misfolded Proteins and Dysfunctional Organelles on Autophagy Menu

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Metabolic fingerprints in testicular biopsies from type 1 diabetic patients

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The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease

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Mitochondria: The gateway for tamoxifen-induced liver injury

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MISFOLDED BRI2 ECTODOMAIN ACTIVATES CRITICAL PATHOLOGICAL PATHWAYS INVOLVED IN EARLY STAGES OF ALZHEIMER'S DISEASE

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The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease

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Protective Effect of Leptin and Ghrelin against Toxicity Induced by Amyloid- beta Oligomers in a Hypothalamic cell Line

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Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes

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Metformin and male reproduction: Effects on Sertoli cell metabolism

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Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?

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Prospective phospholipid markers for skin sensitization prediction in keratinocytes: A phospholipidomic approach

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Otanthus maritimus (L.) Hoffmanns. &amp; Link as a source of a bioactive and fragrant oil

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Antifungal and anti-inflammatory potential of Lavandula stoechas and Thymus herba-barona essential oils

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High-sugar diets, type 2 diabetes and Alzheimer's disease

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Margotia gummifera essential oil as a source of anti-inflammatory drugs

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Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

Alves, M.G.; Neuhaus-Oliveira, A.; Moreira, P.I.; Socorro, S.; Oliveira, P.F., 2013. Reproductive Toxicology. 81 - 88. 38. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876339594&partnerID=MN8TOARS . 10.1016/j.reprotox.2013.03.005 . Reproductive Toxicology

UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats

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New compounds, chemical composition, antifungal activity and cytotoxicity of the essential oil from Myrtus nivellei Batt. &amp; Trab.; An endemic species of Central Sahara

Bouzabata, A.; Bazzali, O.; Cabral, C.; Gonçalves, M.J.; Cruz, M.T.; Bighelli, A.; Cavaleiro, C.; et al, 2013. Journal of Ethnopharmacology. 613 - 620. 3. 149. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884415386&partnerID=MN8TOARS . 10.1016/j.jep.2013.06.054 . Journal of Ethnopharmacology

Mechanism of inhibition of mitochondrial ATP synthase by 17ß-Estradiol

Moreno, A.J.M.; Moreira, P.I.; Custódio, J.B.A.; Santos, M.S., 2013. Journal of Bioenergetics and Biomembranes. 261 - 270. 3. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878642515&partnerID=MN8TOARS . 10.1007/s10863-012-9497-1 . Journal of Bioenergetics and Biomembranes

Essential oil of common sage (Salvia officinalis L.) from Jordan: Assessment of safety in mammalian cells and its antifungal and anti-inflammatory potential

Abu-Darwish, M.S.; Cabral, C.; Ferreira, I.V.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Al-Bdour, T.H.; Salgueiro, L., 2013. BioMed Research International. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886511600&partnerID=MN8TOARS . 10.1155/2013/538940 . BioMed Research International

Hormonal control of Sertoli cell metabolism regulates spermatogenesis

Alves, M.G.; Rato, L.; Carvalho, R.A.; Moreira, P.I.; Socorro, S.; Oliveira, P.F., 2013. Cellular and Molecular Life Sciences. 777 - 793. 5. 70. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873719667&partnerID=MN8TOARS . 10.1007/s00018-012-1079-1 . Cellular and Molecular Life Sciences

Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: Potential benefits for wound healing

Moura, J.; Da Silva, L.; Cruz, M.T.; Carvalho, E., 2013. Archives of Dermatological Research. 557 - 569. 7. 305. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883240109&partnerID=MN8TOARS . 10.1007/s00403-013-1381-2 . Archives of Dermatological Research

Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions

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The combination of the antiestrogen endoxifen with all-trans-retinoic acid has anti-proliferative and anti-migration effects on melanoma cells without inducing significant toxicity in non-neoplasic cells

Ribeiro, M.P.C.; Silva, F.S.G.; Paixão, J.; Santos, A.E.; Custódio, J.B.A., 2013. European Journal of Pharmacology. 354 - 362. 1-3. 715. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885471345&partnerID=MN8TOARS . 10.1016/j.ejphar.2013.04.038 . European Journal of Pharmacology

Ellagitannin-enriched fraction from Fragaria vesca leaves induces G2/M cell cycle arrest in the human hepatocellular carcinoma cell line HepG2

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Development of an in vitro dendritic cell-based test for skin sensitizer identification

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NO radical scavenging and iNOS expression inhibition by Cytisus multiflorus

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Type 2 diabetic and alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies

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Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasome and nuclear factor-¿B pathway inhibition: contribution of chlorogenic acid.

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Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: Implications for Alzheimer's disease

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Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease

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Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

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Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links

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Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration

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Hyperglycemia, hypoglycemia and dementia: Role of mitochondria and uncoupling proteins

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Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes

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Molecular mechanisms beyond glucose transport in diabetes-related male infertility

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Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H 2O2

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Activation of the endoplasmic reticulum stress response by the amyloid-beta 1-40 peptide in brain endothelial cells

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Inhibition of mitochondrial cytochrome c oxidase potentiates Aß-induced ER stress and cell death in cortical neurons

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Effect of a-Synuclein on amyloid ß-Induced toxicity: Relevance to lewy body variant of alzheimer disease

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Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers

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Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance

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Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-¿B and MAPK activation in macrophages

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Cymbopogon citratus industrial waste as source of an anti-inflammatory drug

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The antiestrogen endoxifen protects rat liver mitochondria from permeability transition pore opening and oxidative stress at concentrations that do not affect the phosphorylation efficiency

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Effects of all-trans-retinoic acid on the permeability transition and bioenergetic functions of rat liver mitochondria in combination with endoxifen

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Defective HIF signaling pathway and brain response to hypoxia in neurodegenera-tive diseases: Not an Iffy question!

Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, R.X.; Plácido, A.I.; Candeias, E.; Duarte, A.I.; Moreira, P.I., 2013. Current Pharmaceutical Design. 6809 - 6822. 38. 19. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884829985&partnerID=MN8TOARS . Current Pharmaceutical Design

Anti-inflammatory potential of Lavandula viridis esential oil

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Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1a

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Role of the extra-cellular danger signal adenosine-5 '-triphosphate on the 1-fluoro-2,4-dinitrobenzene-induced maturation of THP-1 cells

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Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover

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Targeting proteasome and autophagy with Fragaria Vesca L

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Immunostimulant activity of Uncaria Tomentosa and its tannins

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Lavandula luisieri essential oil as a source of antifungal drugs

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Composition and biological activity of the essential oil from Thapsia minor, a new source of geranyl acetate

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Endoplasmic reticulum stress: A new playER in tauopathies

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Essential oil of juniperus communis subsp. alpina (Suter) Celak needles: Chemical composition, antifungal activity and cytotoxicity

Cabral, C.; Francisco, V.; Cavaleiro, C.; Gonçalves, M.J.; Cruz, M.T.; Sales, F.; Batista, M.T.; Salgueiro, L., 2012. Phytotherapy Research. 1352 - 1357. 9. 26. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866116136&partnerID=MN8TOARS . 10.1002/ptr.3730 . Phytotherapy Research

Composition, antifungal activity and cytotoxicity of the essential oils of Seseli tortuosum L. and Seseli montanum subsp. peixotoanum (Samp.) M. Laínz from Portugal

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Profiling changes triggered during maturation of dendritic cells: A lipidomic approach

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Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

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Antioxidant activity of polyphenol-enriched fractions from Agrimonia Eupatoria L. infusion

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Guidelines for the use and interpretation of assays for monitoring autophagy

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The impairment of insulin signaling in Alzheimer's disease

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Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation

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Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions

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Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.

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Amyloid-Beta Peptide 1-42 Causes Microtubule Deregulation through N-methyl-D-aspartate Receptors in Mature Hippocampal Cultures

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Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats

Moreira, P.I.; Custódio, J.B.A.; Nunes, E.; Moreno, A.; Seiça, R.; Oliveira, C.R.; Santos, M.S., 2007. Toxicology and Applied Pharmacology. 102 - 110. 1. 221. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247869542&partnerID=MN8TOARS . 10.1016/j.taap.2007.02.006 . Toxicology and Applied Pharmacology

Iron: The redox-active center of oxidative stress in Alzheimer disease

Castellani, R.J.; Moreira, P.I.; Liu, G.; Dobson, J.; Perry, G.; Smith, M.A.; Zhu, X., 2007. Neurochemical Research. 1640 - 1645. 10. 32. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548744723&partnerID=MN8TOARS . 10.1007/s11064-007-9360-7 . Neurochemical Research

Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets

Nunes, E.; Peixoto, F.; Louro, T.; Sena, C.M.; Santos, M.S.; Matafome, P.; Moreira, P.I.; Seiça, R., 2007. Acta Diabetologica. 121 - 130. 3. 44. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548177719&partnerID=MN8TOARS . 10.1007/s00592-007-0252-8 . Acta Diabetologica

Does mitochondria impairment affect endoplasmic reticulum function during amyloid-beta toxicity?

Costa, R.; Ferreiro, E.; Oliveira, C. R.; Pereira, C.; Costa, Rui Miguel Oliveira da; Ferreiro, Elisabete; Resende de Oliveira, Catarina; Pereira, Cláudia, 2007. Journal of Neurochemistry. 68 - 69. Supplement. 102. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000248991600162&KeyUID=WOS:000248991600162 . published Journal of Neurochemistry

Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

Nunomura, A.; Moreira, P.I.; Lee, H.G.; Zhu, X.; Castellani, R.J.; Smith, M.A.; Perry, G., 2007. CNS and Neurological Disorders - Drug Targets. 411 - 423. 6. 6. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-41749088686&partnerID=MN8TOARS . 10.2174/187152707783399201 . CNS and Neurological Disorders - Drug Targets

Erratum: Increased autophagic degradation of mitochondria in Alzheimer disease (Autophagy)

Moreira, P.I.; Siedlak, S.L.; Wang, X.; Santos, M.S.; Oliveira, C.R.; Tabaton, M.; Nunomura, A.; et al, 2007. Autophagy. 614 - 615. 6. 3. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35848931249&partnerID=MN8TOARS . Autophagy

The key role of oxidative stress in alzheimer's disease

Moreira, P.I.; Nunomura, A.; Honda, K.; Aliev, G.; Casadesus, G.; Zhu, X.; Smith, M.A.; Perry, G., 2007. Oxidative Stress and Neurodegenerative Disorders. 267 - 281. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882487316&partnerID=MN8TOARS . 10.1016/B978-044452809-4/50153-8 . Oxidative Stress and Neurodegenerative Disorders

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes

Moreira, P.I.; Santos, M.S.; Seiça, R.; Oliveira, C.R., 2007. Journal of the Neurological Sciences. 206 - 214. 1-2. 257. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249821079&partnerID=MN8TOARS . 10.1016/j.jns.2007.01.017 . Journal of the Neurological Sciences

Alzheimer's disease: A lesson from mitochondrial dysfunction

Moreira, P.I.; Santos, M.S.; Oliveira, C.R., 2007. Antioxidants and Redox Signaling. 1621 - 1630. 10. 9. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34648831384&partnerID=MN8TOARS . 10.1089/ars.2007.1703 . Antioxidants and Redox Signaling

Oxidative RNA damage and neurodegeneration

Nunomura, A.; Moreira, P.I.; Takeda, A.; Smith, M.A.; Perry, G., 2007. Current Medicinal Chemistry. 2968 - 2975. 28. 14. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36849076772&partnerID=MN8TOARS . 10.2174/092986707782794078 . Current Medicinal Chemistry

Erratum: Autophagocytosis of mitochondria is prominent in Alzheimer disease (Journal of Neuropathology and Experimental Neurology (2007) 66, (525-532))

Moreira, P.I.; Siedlak, S.L.; Wang, X.; Santos, M.S.; Oliveira, C.R.; Tabaton, M.; Nunomura, A.; et al, 2007. Journal of Neuropathology and Experimental Neurology. 7. 66. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447321588&partnerID=MN8TOARS . 10.1097/01.jnen.0000263876.99435.cb . Journal of Neuropathology and Experimental Neurology

Differential CXCR4 expression induced by skin sensitizers or irritants in dendritic cell models

Neves, B.; Cruz, M. T.; Goncalo, M.; Figueiredo, A.; Duarte, C. B.; Lopes, M. C., 2007. Journal of Investigative Dermatology. S5 - S5. 127. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000249933400026&KeyUID=WOS:000249933400026 . Journal of Investigative Dermatology

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts

Moreira, P.I.; Harris, P.L.R.; Zhu, X.; Santos, M.S.; Oliveira, C.R.; Smith, M.A.; Perry, G., 2007. Journal of Alzheimer's Disease. 195 - 206. 2. 12. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34848890388&partnerID=MN8TOARS . Journal of Alzheimer's Disease

Neurodegeneration in Alzheimer's disease: Inter-organelle cross-talk and oxidative stress in cell life and death decisions

Ferreiro, Elisabete; Resende, Rosa; Costa, Rui Miguel Oliveira da; Moreira, Paula Isabel; Morais Cardoso, Sandra; Pereira, Cláudia; Resende de Oliveira, Catarina; et al, 2007. Free Radical Research. S11 - S11. 41. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300021&KeyUID=WOS:000252296300021 . Free Radical Research

Effect of skin sensitizers on inducible nitric oxide synthase expression and nitric oxide production in skin dendritic cells: Role of different immunosuppressive drugs

Cruz, M.T.; Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2007. Immunopharmacology and Immunotoxicology. 225 - 241. 2. 29. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548553284&partnerID=MN8TOARS . 10.1080/08923970701512304 . Immunopharmacology and Immunotoxicology

Neuropathology and treatment of Alzheimer disease: Did we lose the forest for the trees?

Castellani, R.J.; Zhu, X.; Lee, H.-G.; Moreira, P.I.; Perry, G.; Smith, M.A., 2007. Expert Review of Neurotherapeutics. 473 - 485. 5. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248326079&partnerID=MN8TOARS . 10.1586/14737175.7.5.473 . Expert Review of Neurotherapeutics

Indices of metabolic dysfunction and oxidative stress

Casadesus, G.; Moreira, P.I.; Nunomura, A.; Siedlak, S.L.; Bligh-Glover, W.; Balraj, E.; Petot, G.; Smith, M.A.; Perry, G., 2007. Neurochemical Research. 717 - 722. 4-5. 32. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947593456&partnerID=MN8TOARS . 10.1007/s11064-007-9296-y . Neurochemical Research

Prevention and treatment of Alzheimer disease and aging: Antioxidants

Liu, Q.; Xie, F.; Rolston, R.; Moreira, P.I.; Nunomura, A.; Zhu, X.; Smith, M.A.; Perry, G., 2007. Mini-Reviews in Medicinal Chemistry. 171 - 180. 2. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847776693&partnerID=MN8TOARS . 10.2174/138955707779802552 . Mini-Reviews in Medicinal Chemistry

Telomeres and telomerase in Alzheimer's disease: Epiphenomena or a new focus for therapeutic strategy?

Franco, S.; Blasco, M.A.; Siedlak, S.L.; Harris, P.L.R.; Moreira, P.I.; Perry, G.; Smith, M.A., 2006. Alzheimer's and Dementia. 164 - 168. 3. 2. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744931650&partnerID=MN8TOARS . 10.1016/j.jalz.2006.03.001 . Alzheimer's and Dementia

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

Moreira, P.I.; Zhu, X.; Lee, H.-G.; Honda, K.; Smith, M.A.; Perry, G., 2006. Mechanisms of Ageing and Development. 501 - 506. 6. 127. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646160622&partnerID=MN8TOARS . 10.1016/j.mad.2006.01.024 . Mechanisms of Ageing and Development

Compensatory responses induced by oxidative stress in Alzheimer disease

Moreira, P.I.; Zhu, X.; Liu, Q.; Honda, K.; Siedlak, S.L.; Harris, P.L.; Smith, M.A.; Perry, G., 2006. Biological Research. 7 - 13. 1. 39. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745840777&partnerID=MN8TOARS . Biological Research

Foreword: Mitochondria in Alzheimer disease

Moreira, P.I.; Oliveira, C., 2006. Journal of Alzheimer's Disease. 2. 9. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746065622&partnerID=MN8TOARS . Journal of Alzheimer's Disease

Therapeutic options in Alzheimer's disease

Moreira, P.I.; Zhu, X.; Nunomura, A.; Smith, M.A.; Perry, G., 2006. Expert Review of Neurotherapeutics. 897 - 910. 6. 6. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745486884&partnerID=MN8TOARS . 10.1586/14737175.6.6.897 . Expert Review of Neurotherapeutics

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity

Ferreiro, E.; Resende, R.; Costa, R.; Oliveira, C.R.; Pereira, C.M.F., 2006. Neurobiology of Disease. 669 - 678. 3. 23. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747195017&partnerID=MN8TOARS . 10.1016/j.nbd.2006.05.011 . Neurobiology of Disease

Presenilin mutation: A deadly first hit in Alzheimer disease - A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice"

Zhu, X.; Lee, H.-G.; Moreira, P.I.; Smith, M.A.; Perry, G., 2006. Free Radical Biology and Medicine. 737 - 739. 5. 40. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644659794&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2005.12.028 . Free Radical Biology and Medicine

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.

Nunomura, A.; Castellani, R.J.; Lee, H.G.; Moreira, P.I.; Zhu, X.; Perry, G.; Smith, M.A., 2006. Science of aging knowledge environment : SAGE KE. 8. 2006. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744531637&partnerID=MN8TOARS . 10.1126/sageke.2006.8.pe10 . Science of aging knowledge environment : SAGE KE

Insulin attenuates diabetes-related mitochondrial alterations: A comparative study

Moreira, P.I.; Rolo, A.P.; Sena, C.; Seiça, R.; Oliveira, C.R.; Santos, M.S., 2006. Medicinal Chemistry. 299 - 308. 3. 2. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746153746&partnerID=MN8TOARS . 10.2174/157340606776930754 . Medicinal Chemistry

Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure

Moreira, P.I.; Custódio, J.; Moreno, A.; Oliveira, C.R.; Santos, M.S., 2006. Journal of Biological Chemistry. 10143 - 10152. 15. 281. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744518169&partnerID=MN8TOARS . 10.1074/jbc.M510249200 . Journal of Biological Chemistry

Brain and brawn: Parallels in oxidative strength

Moreira, P.I.; Honda, K.; Zhu, X.; Nunomura, A.; Casadesus, G.; Smith, M.A.; Perry, G., 2006. Neurology. 2 SUPPL. 1. 66. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644850568&partnerID=MN8TOARS . Neurology

Involvement of oxidative stress in Alzheimer disease

Nunomura, A.; Castellani, R.J.; Zhu, X.; Moreira, P.I.; Perry, G.; Smith, M.A., 2006. Journal of Neuropathology and Experimental Neurology. 631 - 641. 7. 65. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747861696&partnerID=MN8TOARS . 10.1097/01.jnen.0000228136.58062.bf . Journal of Neuropathology and Experimental Neurology

Excitotoxicity mediated by Ca2+-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor

Santos, A.E.; Duarte, C.B.; Iizuka, M.; Barsoumian, E.L.; Ham, J.; Lopes, M.C.; Carvalho, A.P.; Carvalho, A.L., 2006. Cell Death and Differentiation. 652 - 660. 4. 13. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644935364&partnerID=MN8TOARS . 10.1038/sj.cdd.4401785 . Cell Death and Differentiation

The key role of mitochondria in Alzheimer's disease

Moreira, P.I.; Cardoso, S.M.; Santos, M.S.; Oliveira, C.R., 2006. Journal of Alzheimer's Disease. 101 - 110. 2. 9. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746066329&partnerID=MN8TOARS . Journal of Alzheimer's Disease

Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease

Zhu, X.; Perry, G.; Moreira, P.I.; Aliev, G.; Cash, A.D.; Hirai, K.; Smith, M.A., 2006. Journal of Alzheimer's Disease. 147 - 153. 2. 9. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746089859&partnerID=MN8TOARS . Journal of Alzheimer's Disease

A second look into the oxidant mechanisms in Alzheimer's disease

Moreira, P.I.; Oliveira, C.R.; Santos, M.S.; Nunomura, A.; Honda, K.; Zhu, X.; Smith, M.A.; Perry, G., 2005. Current Neurovascular Research. 179 - 184. 2. 2. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18744402471&partnerID=MN8TOARS . 10.2174/1567202053586758 . Current Neurovascular Research

Endoplasmic reticulum dysfunction and oxidative stress induced by the prion peptide

Ferreiro, EB; Oliveira, CR; Pereira, CM, 2005. Journal of Neurochemistry. 174 - 175. 94. 2005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000231673401076&KeyUID=WOS:000231673401076 . Journal of Neurochemistry

Chronological primacy of oxidative stress in Alzheimer disease

Smith, M.A.; Nunomura, A.; Lee, H.-G.; Zhu, X.; Moreira, P.I.; Avila, J.; Perry, G., 2005. Neurobiology of Aging. 579 - 580. 5. 26. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-13644249113&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2004.09.021 . Neurobiology of Aging

Mitogen- and stress-activated protein kinase 1: Convergence of the ERK and p38 pathways in Alzheimer's disease

Webber, K.M.; Smith, M.A.; Lee, H.-G.; Harris, P.L.; Moreira, P.; Perry, G.; Zhu, X., 2005. Journal of Neuroscience Research. 554 - 560. 4. 79. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-14144250344&partnerID=MN8TOARS . 10.1002/jnr.20380 . Journal of Neuroscience Research

The sensitizers nickel sulfate and 2,4-dinitrofluorobenzene increase CD40 and IL-12 receptor expression in a fetal skin dendritic cell line

Vital, A.L.; Gonçalo, M.; Cruz, M.T.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2005. Bioscience Reports. 191 - 202. 3. 24. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23944504971&partnerID=MN8TOARS . 10.1007/s10540-005-2580-7 . Bioscience Reports

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies

Pereira, C.; Agostinho, P.; Moreira, P.I.; Cardoso, S.M.; Oliveira, C.R., 2005. Current Drug Targets: CNS and Neurological Disorders. 383 - 403. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144463734&partnerID=MN8TOARS . 10.2174/1568007054546117 . Current Drug Targets: CNS and Neurological Disorders

Oxidative stress and neurodegeneration

Moreira, P.I.; Smith, M.A.; Zhu, X.; Nunomura, A.; Castellani, R.J.; Perry, G., 2005. Annals of the New York Academy of Sciences. 545 - 552. 1043. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23744439419&partnerID=MN8TOARS . 10.1196/annals.1333.062 . Annals of the New York Academy of Sciences

Alzheimer's disease: An intracellular movement disorder?

Zhu, X.; Moreira, P.I.; Smith, M.A.; Perry, G., 2005. Trends in Molecular Medicine. 391 - 393. 9. 11. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-24344483065&partnerID=MN8TOARS . 10.1016/j.molmed.2005.07.002 . Trends in Molecular Medicine

Neurodegenerative pathways in Parkinson's disease: Therapeutic strategies

Cardoso, S.M.; Moreira, P.I.; Agostinho, P.; Pereira, C.; Oliveira, C.R., 2005. Current Drug Targets: CNS and Neurological Disorders. 405 - 419. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144431757&partnerID=MN8TOARS . 10.2174/1568007054546072 . Current Drug Targets: CNS and Neurological Disorders

Insulin protects against amyloid ß-peptide toxicity in brain mitochondria of diabetic rats

Moreira, P.I.; Santos, M.S.; Sena, C.; Seiça, R.; Oliveira, C.R., 2005. Neurobiology of Disease. 628 - 637. 3. 18. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-14744294296&partnerID=MN8TOARS . 10.1016/j.nbd.2004.10.017 . Neurobiology of Disease

Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen

Moreira, P.I.; Custódio, J.B.; Oliveira, C.R.; Santos, M.S., 2005. Neuropharmacology. 435 - 447. 3. 48. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-13844275276&partnerID=MN8TOARS . 10.1016/j.neuropharm.2004.10.012 . Neuropharmacology

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies

Pereira, C.; Agostinho, P.; Moreira, P.I.; Cardoso, S.M.; Oliveira, C.R., 2005. Current Drug Targets: CNS and Neurological Disorders. 383 - 403. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144463734&partnerID=MN8TOARS . 10.2174/1568007054546117 . Current Drug Targets: CNS and Neurological Disorders

The crosstalk between the endoplasmic reticulum and mitochondria in Alzheimer's disease

Cardoso, SM; Ferreiro, E; Oliveira, CR; Pereira, C, 2005. Febs Journal. 55 - 55. 272. 2005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000234826100186&KeyUID=WOS:000234826100186 . Febs Journal

Oxidative stress mechanisms and potential therapeutics in Alzheimer disease

Moreira, P.I.; Siedlak, S.L.; Aliev, G.; Zhu, X.; Cash, A.D.; Smith, M.A.; Perry, G., 2005. Journal of Neural Transmission. 921 - 932. 7. 112. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-20944449836&partnerID=MN8TOARS . 10.1007/s00702-004-0242-8 . Journal of Neural Transmission

Protective effect of zinc on amyloid-ß 25-35 and 1-40 mediated toxicity

Cardoso, S.M.; Rego, A.C.; Pereira, C.; Oliveira, C.R., 2005. Neurotoxicity Research. 273 - 281. 4. 7. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-27744456147&partnerID=MN8TOARS . 10.1007/BF03033885 . Neurotoxicity Research

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

Honda, K.; Smithi, M.A.; Zhu, X.; Baus, D.; Merrick, W.C.; Tartakoff, A.M.; Hattier, T.; et al, 2005. Journal of Biological Chemistry. 20978 - 20986. 22. 280. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-20444383489&partnerID=MN8TOARS . 10.1074/jbc.M500526200 . Journal of Biological Chemistry

Tau phosphorylation in Alzheimer's disease: Pathogen or protector?

Lee, H.-G.; Perry, G.; Moreira, P.I.; Garrett, M.R.; Liu, Q.; Zhu, X.; Takeda, A.; Nunomura, A.; Smith, M.A., 2005. Trends in Molecular Medicine. 164 - 169. 4. 11. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-17044435830&partnerID=MN8TOARS . 10.1016/j.molmed.2005.02.008 . Trends in Molecular Medicine

Aeroallergens sensitization in an allergic paediatric population of Cova da Beira, Portugal.

Loureiro, G; Rabaca, M A; Blanco, B; Andrade, S; Chieira, C; Pereira, C, 2005. Allergologia et immunopathologia. 192 - 8. 4. 33. 2005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:16045856&KeyUID=MEDLINE:16045856 . 10.1157/13077742 . Allergologia et immunopathologia

Metal ions and oxidative protein modification in neurological disease

Sayre, L.M.; Moreira, P.I.; Smith, M.A.; Perry, G., 2005. Annali dell'Istituto Superiore di Sanita. 143 - 164. 2. 41. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-31644435822&partnerID=MN8TOARS . Annali dell'Istituto Superiore di Sanita

Alzheimer's disease and oxidative stress: The old problem remains unsolved

Moreira, P.I.; Honda, K.; Liu, Q.; Aliev, G.; Oliveira, C.R.; Santos, M.S.; Zhu, X.; Smith, M.A.; Perry, G., 2005. Current Medicinal Chemistry - Central Nervous System Agents. 51 - 62. 1. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-15344351142&partnerID=MN8TOARS . Current Medicinal Chemistry - Central Nervous System Agents

Neurodegenerative pathways in Parkinson's disease: Therapeutic strategies

Cardoso, S.M.; Moreira, P.I.; Agostinho, P.; Pereira, C.; Oliveira, C.R., 2005. Current Drug Targets: CNS and Neurological Disorders. 405 - 419. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144431757&partnerID=MN8TOARS . 10.2174/1568007054546072 . Current Drug Targets: CNS and Neurological Disorders

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

Liu, Q.; Smith, M.A.; Avilá, J.; DeBernardis, J.; Kansal, M.; Takeda, A.; Zhu, X.; et al, 2005. Free Radical Biology and Medicine. 746 - 754. 6. 38. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-13844267510&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2004.11.005 . Free Radical Biology and Medicine

Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line

Cruz, M.T.; Gonçalo, M.; Paiva, A.; Morgado, J.M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2005. Archives of Dermatological Research. 43 - 47. 1. 297. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-25644435637&partnerID=MN8TOARS . 10.1007/s00403-005-0574-8 . Archives of Dermatological Research

Therapeutic opportunities in Alzheimer Disease: One for all or all for one?

Marlatt, M.W.; Webber, K.M.; Moreira, P.I.; Lee, H.-G.; Casadesus, G.; Honda, K.; Zhu, X.; Perry, G.; Smith, M.A., 2005. Current Medicinal Chemistry. 1137 - 1147. 10. 12. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18544380930&partnerID=MN8TOARS . 10.2174/0929867053764644 . Current Medicinal Chemistry

Redox metals and oxidative abnormalities in human prion diseases

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CoQ10 therapy attenuates amyloid ß-peptide toxicity in brain mitochondria isolated from aged diabetic rats

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Oxidative damage and Alzheimer's disease: Are antioxidant therapies useful?

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The Sensitizers Nickel Sulfate and 2,4-dinitrofluorobenzene Increase CD40 and IL-12 Receptor Expression in a Fetal Skin Dendritic Cell Line

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Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-ß peptide

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Hydroxytamoxifen protects against oxidative stress in brain mitochondria

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Effect of streptozotocin-induced diabetes on rat brain mitochondria

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Therapeutic potential of oxidant mechanisms in Alzheimer's disease

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Staying connected: Synapses in alzheimer disease

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Neurofilament proteins in neurodegenerative diseases

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Neuroprotection strategies: Effect of vinpocetinein in vitro oxidative stress models | Estratégias de neuroprotecção: Efeito da vimpocetina em modelos in vitro de stresse oxidativo

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Increased vulnerability of brain mitochondria in diabetic (goto-kakizaki) rats with aging and amyloid-ß exposure

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[Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models].

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The Sensitizer 2,4-Dinitrofluorobenzene Activates Caspase-3 and Induces Cell Death in a Skin Dendritic Cell Line

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Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-¿B activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

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The sensitizer 2,4-dinitrofluorobenzene activates caspase-3 and induces cell death in a skin dendritic cell line

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Differential activation of nuclear factor kappa B subunits in a skin dendritic cell line in response to the strong sensitizer 2,4-dinitrofluorobenzene.

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Effect of amyloid ß-peptide on permeability transition pore: A comparative study

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Differential postreceptor signaling events triggered by excitotoxic stimulation of different ionotropic glutamate receptors in retinal Neurons

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LPS induction of IkB-¿ degradation and iNOS expression in a skin dendritic cell line is prevented by the Janus Kinase 2 inhibitor, tyrphostin B42

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Granulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line

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Amyloid ß-peptide promotes permeability transition pore in brain mitochondria

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Susceptibility to ß-amyloid-induced toxicity is decreased in Goto- Kakizaki diabetic rats: Involvement of oxidative stress

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Vinpocetine attenuates the metabolic dysfunction induced by amyloid beta-peptides in PC12 cells

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Effect of Zinc Ions on the Cytotoxicity Induced by the Amyloid beta-Peptide

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Effect of zinc ions on the cytotoxicity induced by the amyloid ß- peptide

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Synaptosomal response to oxidative stress: Effect of vinpocetine

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Effect of Zinc Ions on the Cytotoxicity Induced by the Amyloid beta-Peptide

Moreira, Paula; Pereira, Claudia; Santos, Maria S.; Oliveira, Catarina, 2000. Antioxidants & Redox Signaling. 317 - 325. 2. 2. 2000. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000207500700014&KeyUID=WOS:000207500700014 . 10.1089/ars.2000.2.2-317 . Antioxidants & Redox Signaling

Effect of zinc ions on the cytotoxicity induced by the amyloid ß- peptide

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Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis

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Susceptibility to ß-amyloid-induced toxicity is decreased in Goto- Kakizaki diabetic rats: Involvement of oxidative stress

Pereira, C.; Moreira, P.; Seiça, R.; Santos, M.S.; Oliveira, C.R., 2000. Experimental Neurology. 383 - 391. 1. 161. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034051172&partnerID=MN8TOARS . 10.1006/exnr.1999.7270 . Experimental Neurology

Mitochondrial function is differentially affected upon oxidative stress

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Involvement of oxidative stress on the impairment of energy metabolism induced by Aß peptides on PC12 cells: Protection by antioxidants

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Involvement of JAK2 and MAPK on type II nitric oxide synthase expression in skin-derived dendritic cells

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Photosensitization of lymphoblastoid cells with phthalocyanines at different saturating incubation times

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Mitochondrial function impairment induced by amyloid beta-peptide on PC12 cells

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Calcium-dependent nitric oxide synthase activity in rat thymocytes

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Inhibition of ROS production prevents IL-1ß-induced iNOS expression in articular chondrocytes

Mendes, AF; Wong, H; Caramona, MM; Carvalho, AP; Lopes, MC; Cruz, TF, 1998. Naunyn-Schmiedeberg's Archives of Pharmacology. 1998. https://publons.com/wos-op/publon/10621892/ . Naunyn-Schmiedeberg's Archives of Pharmacology

The protective effect of vitamin E, idebenone and reduced glutathione on free radical mediated injury in rat brain synaptosomes

Cardoso, S.M.; Pereira, C.; Oliveira, C.R., 1998. Biochemical and Biophysical Research Communications. 703 - 710. 3. 246. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032577242&partnerID=MN8TOARS . 10.1006/bbrc.1998.8563 . Biochemical and Biophysical Research Communications

Sulfonated Chloroaluminum Phthalocyanine Incorporates into Human Plasma Lipoproteins: Photooxidation of Low-Density Lipoproteins

Santos, A.E.; Laranjinha, J.A.N.; Almeida, L.M., 1998. Photochemistry and Photobiology. 378 - 385. 4. 67. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032040364&partnerID=MN8TOARS . Photochemistry and Photobiology

Metabolic inhibition increases glutamate susceptibility on a PC12 cell line

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Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress

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Interaction between polyalkylcyanoacrylate nanoparticles and peritoneal macrophages: MTT metabolism, NBT reduction, and NO production

Cruz, T.; Gaspar, R.; Donato, A.; Lopes, C., 1997. Pharmaceutical Research. 73 - 79. 1. 14. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031042535&partnerID=MN8TOARS . 10.1023/A:1012059501947 . Pharmaceutical Research

Contribution of plasma membrane and endoplasmic reticulum Ca2+-ATPases to the synaptosomal [Ca2+]i increase during oxidative stress

Pereira, C.; Ferreira, C.; Carvalho, C.; Oliveira, C., 1996. Brain Research. 269 - 277. 1-2. 713. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029928472&partnerID=MN8TOARS . 10.1016/0006-8993(95)01554-X . Brain Research

Regulation of intracellular [Ca2+] and GABA release by presynaptic GABAB receptors in rat cerebrocortical synaptosomes

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