Publications
Information about journal articles, updated at 01-12-2024, from platform CIÊNCIAVITAE.
Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions
Cavaleiro, Carla; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Valero, Jorge; Mota, Sandra I.; Ferreiro, Elisabete, Frontiers in Molecular Neuroscience. 16. 2023. http://dx.doi.org/10.3389/fnmol.2023.1229728 . 10.3389/fnmol.2023.1229728 . Frontiers in Molecular Neuroscience
Uncovering the Early Events Associated with Oligomeric Aß-Induced Src Activation
Sandra I. Mota; Lígia Fão; Patrícia Coelho; A. Cristina Rego, Antioxidants. 2023. https://doi.org/10.3390/antiox12091770 . 10.3390/antiox12091770 . Antioxidants
Recent Advances in Extracellular Vesicles in Amyotrophic Lateral Sclerosis and Emergent Perspectives
Gonçalo J. M. Afonso; Carla Cavaleiro; Jorge Valero; Sandra I. Mota; Elisabete Ferreiro, Cells. 2023. https://doi.org/10.3390/cells12131763 . 10.3390/cells12131763 . Cells
Mitochondrial and redox modifications in early stages of Huntington's disease
Lopes, Carla; Ferreira, I. Luísa; Maranga, Carina; Beatriz, Margarida; Mota, Sandra I.; Sereno, José; Castelhano, João; et al, Redox Biology. 56. 2022. http://dx.doi.org/10.1016/j.redox.2022.102424 . 10.1016/j.redox.2022.102424 . Redox Biology
Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders
Cláudia Deus; Deus, CM; Henrique Tavares; Margarida Beatriz; Sandra Mota; C Lopes, Cells. 2364 - 2364. 15. 11. 2022. http://dx.doi.org/10.3390/cells11152364 . 10.3390/cells11152364 . Cells
Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases.
Coelho P; Fão L; Mota S; Rego AC, Ageing research reviews. 2022. http://europepmc.org/abstract/med/35714855 . 10.1016/j.arr.2022.101667 . Ageing research reviews
Restoration of c-Src/Fyn proteins rescues mitochondrial dysfunction in Huntington's Disease.
Fão L; Coelho P; Duarte L; Vilaça R; Hayden M; Mota S; Rego AC, Antioxidants & redox signaling. 2022. http://europepmc.org/abstract/med/35651273 . 10.1089/ars.2022.0001 . Antioxidants & redox signaling
Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma.
Geva M; Gershoni-Emek N; Naia L; Ly P; Mota S; Rego AC; Hayden MR; Levin LA, Scientific reports. 2021. http://europepmc.org/abstract/med/34753986 . 10.1038/s41598-021-01077-w . Scientific reports
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model
Sandra I. Mota; Inês Pita; Rodolfo Águas; Slah Tagorti; Ashraf Virmani; Frederico C. Pereira; A. Cristina Rego, Archives of Toxicology. 2769 - 2784. 8. 95. 2021. https://doi.org/10.1007/s00204-021-03104-1 . 10.1007/s00204-021-03104-1 . Archives of Toxicology
The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models.
Mota, S.I.; Naia Luana; Philip Ly; Carla Maria Nunes Lopes; Maranga, Carina; Patrícia Coelho; Noga Gershoni-Emek; et al, Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2021. https://doi.org/10.1007/s13311-021-01022-9 . 10.1007/s13311-021-01022-9 . accepted Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model
Ferreiro, Elisabete; Lanzillo, Mariagrazia; Canhoto, Diogo; Carvalho da Silva, António M.; Mota, Sandra I.; Dias, Inês S.; Ferreira, Ildete L.; et al, Neurobiology of Aging. 98 - 113. 92. 2020. http://dx.doi.org/10.1016/j.neurobiolaging.2020.04.003 . 10.1016/j.neurobiolaging.2020.04.003 . Neurobiology of Aging
c-Src regulates Nrf2 activity through PKCd after oxidant stimulus
Fão, Lígia*; Mota, Sandra I.*; Rego, A. Cristina, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 686 - 698. 4. 1866. 2019. http://dx.doi.org/10.1016/j.bbamcr.2019.01.011 . 10.1016/j.bbamcr.2019.01.011 . Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases.
Fão, Lígia; Mota, Sandra; Rego, Ana Cristina, Ageing research reviews. 2019. http://europepmc.org/abstract/med/31415806 . 10.1016/j.arr.2019.100942 . Ageing research reviews
Coriolus versicolor biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus.
Ferreiro E; Pita IR; Mota SI; Valero J; Ferreira NR; Fernandes T; Calabrese V; et al, Oncotarget. 2018. http://europepmc.org/abstract/med/30250640 . 10.18632/oncotarget.25978 . Oncotarget
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease
Mota, S.I.; Costa, R.O.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Dysfunctional synapse in Alzheimer's disease - A focus on NMDA receptors
Mota, S.I.; Ferreira, I.L.; Rego, A.C., Neuropharmacology. 16 - 26. PART A. 76. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886641553&partnerID=MN8TOARS . 10.1016/j.neuropharm.2013.08.013 . Neuropharmacology
Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus - Linking NMDA receptors and the reelin pathway
Mota, S.I.; Ferreira, I.L.; Valero, J.; Ferreiro, E.; Carvalho, A.L.; Oliveira, C.R.; Rego, A.C.; et al, Experimental Neurology. 698 - 709. 261. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908339906&partnerID=MN8TOARS . 10.1016/j.expneurol.2014.07.023 . Experimental Neurology
Amyloid-beta peptide 1-42 causes microtubule deregulation through N-methyl-D-aspartate receptors in mature hippocampal cultures
Mota, S.I.; Ferreira, I.L.; Pereira, C.; Oliveira, C.R.; Rego, A.C., Current Alzheimer Research. 844 - 856. 7. 9. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866468436&partnerID=MN8TOARS . 10.2174/156720512802455322 . Current Alzheimer Research
Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures
Ferreira, I.L.; Bajouco, L.M.; Mota, S.I.; Auberson, Y.P.; Oliveira, C.R.; Rego, A.C., Cell Calcium. 95 - 106. 2. 51. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856958510&partnerID=MN8TOARS . 10.1016/j.ceca.2011.11.008 . Cell Calcium
Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity
Bui, L.-C.; Tomkiewicz, C.; Chevallier, A.; Pierre, S.; Bats, A.-S.; Mota, S.; Raingeaud, J.; et al, Oncogene. 3642 - 3651. 41. 28. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350066363&partnerID=MN8TOARS . 10.1038/onc.2009.224 . Oncogene
5 20 out of 20 Publications
All projects
Information of exclusive responsibility of the researcher 01-12-2024 , from platform CIÊNCIAVITAE.
2022/01/15 - 2025/01/14
Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021/01/01 -
Projeto Estratégico Centro de Inovação em Biomedicina e Biotecnologia
UIDP/04539/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021/01 -
Projeto Estratégico Centro de Inovação em Biomedicina e Biotecnologia
UIDB/04539/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021/10/01 -
Organelle-targeted Radiocomplexes for Auger Therapy of Cancer Radiocomplexos Dirigidos a Organelos Celulares para Terapia Auger do Cancro
PTDC/MED-QUI/1554/2020
Researcher
Universidade de Lisboa Instituto Superior Tecnico Campus Tecnológico e Nuclear
Funders: Fundação para a Ciência e a Tecnologia
2018/01/01 - 2018/05
Exploring the role of pridopidine on mitochondrial function and dynamics in Huntington’s disease models
N/A
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: TEVA pharmaceuticals industries ltd.
2018/07 - 2021/03/31
Transcriptional activity modulation in Alzheimer's disease by inhibitors of histone deacetylases
POCI-01-0145-FEDER-032316
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2017 - 2017/09
Supplementation of Coriolus versicolor (biomass) - a nutritional presymptomatic approach against cognitive deficits
N/A
Post-doc Fellow
Funders: Mycology Research Laboratories (MRL) Ltd.
2014 - 2019
H2O2-mediated Src signaling pathways in glutamatergic synapses in Alzheimer's disease models
SFRH/BPD/99219/2013
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2014/01 - 2016/02
Evaluation of oxidative stress and mitochondrial dysfunction in animal models and patients of Huntington’s disease using Cu(II)-ATSM PET
N/A
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Santa Casa da Misericórdia de Lisboa
2011/10 - 2014/12
Genetic susceptibility of multisystemic complications of diabetes type 2: novel biomarkers for diagnosis and monitoring of therapy
Do-IT “DIAMARKER PROJECT”
PhD Student Fellow
Universidade de Coimbra Faculdade de Medicina
Funders: Quadro de referência Estratégica Nacional
2009/01/01 - 2012/12/31
NMDA receptors-associated events and oxidative stress in models of Alzheimer’s disease
SFRH/BD/43430/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2009/03 - 2011/02
Phosphorylation and oxidation of NMDA receptor subunits in Alzheimer’s disease and protective role of memantine
N/A
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: H. Lundbeck A/S
2009/03 - 2011/02
Phosphorylation and oxidation of NMDA receptor subunits in Alzheimer’s disease and protective role of memantine
N/A
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: H. Lundbeck A/S
2008/09/01 - 2010/12
Contribution of N-methyl-D-aspartate receptors subunits to neuronal dysfunction in Alzheimer’s disease
PTDC/SAU-NEU/71675/2006
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2007/10/01 - 2008/08/31
Polluants Organiques persistants (POP)_ Migration cellulaire et progression tumorale – ONCOPOP
ANR-02-ESTE-0026
Master Student Fellow
INSERM Délégation Régionale Paris 5
Funders: Agence nationale de la recherche
5 15 out of 15 projects
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