Ricardo D. González

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Ricardo D. González has a Bachelor degree in Genetics and Biotechnology (UTAD), a Master in Forensic Genetics and a Specialization in Bioinformatics and Computational Biology, both from UPorto. At UCoimbra, he is currently a PhD student of the Experimental Biology and Biomedicine program at the Rational Protein Engineering group, with the project "Enzymatic synthesis of RNA-peptide conjugates as potential therapeutics for Covid-19", in collaboration with the Biomaterials and Stem Cell-based Therapeutics group (CNC) and with HBBE - Northumbria University.

Affiliation

University of Coimbra, Institute for Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), Portugal

Publications

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Information about journal articles, updated at 22-12-2024, from platform CIÊNCIAVITAE.

Papain-Mediated Conjugation of Peptide Nucleic Acids to Delivery Peptides: A Density Functional Theory/Molecular Mechanics Metadynamics Study in Aqueous and Organic Solvent

González, Ricardo D.; Carvalho, Alexandra T. P., The Journal of Physical Chemistry B. 2024. http://dx.doi.org/10.1021/acs.jpcb.4c02294 . 10.1021/acs.jpcb.4c02294 . published The Journal of Physical Chemistry B

Near-Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR-Cas9 Ribonucleoprotein for Brain Gene Editing

Simões, Susana; Lino, Miguel; Barrera, Angela; Rebelo, Catarina; Tomatis, Francesca; Vilaça, Andreia; Breunig, Christopher; et al, Angewandte Chemie International Edition. 2024. http://dx.doi.org/10.1002/anie.202401004 . 10.1002/anie.202401004 . Angewandte Chemie International Edition

Designing Cell Delivery Peptides and SARS-CoV-2-Targeting Small Interfering RNAs: A Comprehensive Bioinformatics Study with Generative Adversarial Network-Based Peptide Design and In Vitro Assays

González, Ricardo D.; Susana Simões; Lino Ferreira; Alexandra T. P. Carvalho, Molecular Pharmaceutics. 2023. https://doi.org/10.1021/acs.molpharmaceut.3c00444 . 10.1021/acs.molpharmaceut.3c00444 . Molecular Pharmaceutics

Insights into the Degradation of Polymer-Drug Conjugates by an Overexpressed Enzyme in Cancer Cells

Pedro R. Figueiredo; González, Ricardo D.; Alexandra T. P. Carvalho, Journal of Medicinal Chemistry. 2023. https://doi.org/10.1021/acs.jmedchem.2c01781 . 10.1021/acs.jmedchem.2c01781 . published Journal of Medicinal Chemistry

Human Carboxylesterase 2 in Cocaine Metabolism

Figueiredo, Pedro R.; González, Ricardo D.; Carvalho, Alexandra T.P., Molecular Catalysis. 515. 2021. http://dx.doi.org/10.1016/j.mcat.2021.111938 . 10.1016/j.mcat.2021.111938 . published Molecular Catalysis

All projects

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Information of exclusive responsibility of the researcher 22-12-2024 , from platform CIÊNCIAVITAE.

2020/11/01 - 2024/11/01

Enzymatic synthesis of RNA-peptide conjugates as potential therapeutics for COVID-19

DOI 10.54499/2020.10114.BD

PhD Student Fellow

Universidade de Coimbra Instituto de Investigação Interdisciplinar

Funders: Fundação para a Ciência e a Tecnologia

2020/01/02 - 2020/12/31

Embryonic T-box transcription factor Brachyury: Dissecting its role in prostate cancer biology and clinical application

ICVS_BI_2019_011

Research Fellow

Laboratório Associado ICVS 3B's

Funders: Fundação para a Ciência e a Tecnologia

2019/07/01 - 2019/12/31

Analysis and correlation between the complete genome and brain activity for help in the diagnosis of Alzheimer's disease

AD-EEGWA

Research Fellow

Universidade do Porto Instituto de Patologia e Imunologia Molecular; Universidade do Porto Instituto de Investigação e Inovação em Saúde

Funders: POCTEP - Programa Operativo Cooperação Transfronteiriça Espanha-Portugal

2016/09/22 - 2017/05/01

Influence of the glucocorticoid receptor on microRNAs profile in Triple-Negative Breast Cancer

Friedrich-Baur-Stiftung [54/16]

Master Student Fellow

Universitätsklinikum München Institut für Humangenetik

Funders: Friedrich-Baur-Stiftung; Curt-Bohnewands-Fonds; K.L. Weigand'sche Stiftung; Georg and Traud Gravenhorst Stiftung

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