Publications
Information about journal articles, updated at 02-03-2025, from platform CIÊNCIAVITAE.
Novel steroidal oximes as antiproliferative agents: Design, synthesis and biological activity evaluation
Gomes, Ana R.; Tavares-da-Silva, Elisiário J.; Abrantes, Ana M.; Gonçalves, Ana C.; Alves, Raquel; Botelho, Maria F.; Pires, Ana S.; Roleira, Fernanda M.F., Bioorganic Chemistry. 2025. https://doi.org/10.1016/j.bioorg.2025.108229 . 10.1016/j.bioorg.2025.108229 . Bioorganic Chemistry
Batimastat Induces Cytotoxic and Cytostatic Effects in In Vitro Models of Hematological Tumors
Alves, Raquel; Pires, A.; Jorge, J.; Balça-Silva, J.; Gonçalves, A.C.; Sarmento-Ribeiro, A.B., International journal of molecular sciences. 8. 25. 2024. http://www.scopus.com/inward/record.url?eid=2-s2.0-85191622580&partnerID=MN8TOARS . 10.3390/ijms25084554 . published International journal of molecular sciences
Advancements in Biomarkers and Molecular Targets in Hematological Neoplasias
Gonçalves, A.C.; Alves, Raquel; Sarmento-Ribeiro, A.B., International Journal of Molecular Sciences. 12. 25. 2024. http://www.scopus.com/inward/record.url?eid=2-s2.0-85197199666&partnerID=MN8TOARS . 10.3390/ijms25126570 . published International Journal of Molecular Sciences
Steroidal epoxides as anticancer agents in lung, prostate and breast cancers: The case of 1,2-epoxysteroids
Gomes, A.R.; Tavares-da-Silva, E.J.; Costa, S.C.; Varela, C.L.; Abrantes, A.M.; Gonçalves, A.C.; Alves, Raquel; et al, Biochemical Pharmacology. 225. 2024. http://www.scopus.com/inward/record.url?eid=2-s2.0-85193442470&partnerID=MN8TOARS . 10.1016/j.bcp.2024.116266 . published Biochemical Pharmacology
AZD-7648, a DNA-PK Inhibitor, Induces DNA Damage, Apoptosis, and Cell Cycle Arrest in Chronic and Acute Myeloid Leukemia Cells
Lapa, Beatriz Santos; Costa, Maria Inês; Figueiredo, Diana; Jorge, Joana; Alves, Raquel; Monteiro, Ana Raquel; Serambeque, Beatriz; et al, International Journal of Molecular Sciences. 20. 24. 2023. https://doi.org/10.3390/ijms242015331 . 10.3390/ijms242015331 . published International Journal of Molecular Sciences
Monocytes in the Characterization of Pain in Palliative Patients with Severe Dementia—A Pilot Study
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Teixeira-Veríssimo, Manuel; Andrade, José Paulo; Dourado, Marília, International Journal of Molecular Sciences. 13. 24. 2023. http://dx.doi.org/10.3390/ijms241310723 . 10.3390/ijms241310723 . published International Journal of Molecular Sciences
Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies
Jorge, Joana; Neves, Joana; Alves, Raquel; Geraldes, Catarina; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela, International Journal of Molecular Sciences. 11. 24. 2023. http://dx.doi.org/10.3390/ijms24119167 . 10.3390/ijms24119167 . published International Journal of Molecular Sciences
Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Teixeira-Veríssimo, Manuel; Dourado, Marília; Andrade, José Paulo, Biomedicines. 2. 11. 2023. https://doi.org/10.3390/biomedicines11020380 . 10.3390/biomedicines11020380 . published Biomedicines
Alvespimycin Inhibits Heat Shock Protein 90 and Overcomes Imatinib Resistance in Chronic Myeloid Leukemia Cell Lines
Alves, Raquel; Santos, Diogo; Jorge, Joana; Gonçalves, Ana Cristina; Catarino, Steve; Girão, Henrique; Melo, Joana Barbosa; Sarmento-Ribeiro, Ana Bela, Molecules. 3. 28. 2023. https://doi.org/10.3390/molecules28031210 . 10.3390/molecules28031210 . published Molecules
Antitumor Effect of Brusatol in Acute Lymphoblastic Leukemia Models Is Triggered by Reactive Oxygen Species Accumulation
Jorge, Joana; Magalhães, Nisa; Alves, Raquel; Lapa, Beatriz; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela, Biomedicines. 9. 10. 2022. http://dx.doi.org/10.3390/biomedicines10092207 . 10.3390/biomedicines10092207 . published Biomedicines
Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Ribeiro, André B.; Tenreiro, Rita; Coucelo, Margarida; et al, International Journal of Molecular Sciences. 17. 23. 2022. http://dx.doi.org/10.3390/ijms23179815 . 10.3390/ijms23179815 . published International Journal of Molecular Sciences
Combination of Elacridar with Imatinib Modulates Resistance Associated with Drug Efflux Transporters in Chronic Myeloid Leukemia
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Almeida, António M.; Sarmento-Ribeiro, Ana Bela, Biomedicines. 5. 10. 2022. http://dx.doi.org/10.3390/biomedicines10051158 . 10.3390/biomedicines10051158 . published Biomedicines
Zinc Prevents DNA Damage in Normal Cells but Shows Genotoxic and Cytotoxic Effects in Acute Myeloid Leukemia Cells
Costa, Maria Inês; Lapa, Beatriz Santos; Jorge, Joana; Alves, Raquel; Carreira, Isabel Marques; Sarmento-Ribeiro, Ana Bela; Gonçalves, Ana Cristina, International Journal of Molecular Sciences. 5. 23. 2022. http://dx.doi.org/10.3390/ijms23052567 . 10.3390/ijms23052567 . published International Journal of Molecular Sciences
Can peripheral blood provide good DNA methylation biomarkers in myelodysplastic syndrome?
Jorge, Joana; Gonçalves, Ana Cristina; Cortesão, Emília; Pires, Ana Cláudia; Alves, Raquel; Geraldes, Catarina; Pereira, Amélia; et al, Journal of Molecular and Clinical Medicine. 1. 4. 2021. http://dx.doi.org/10.31083/j.jmcm.2021.01.015 . 10.31083/j.jmcm.2021.01.015 . published Journal of Molecular and Clinical Medicine
Oxidative Stress Parameters Can Predict the Response to Erythropoiesis-Stimulating Agents in Myelodysplastic Syndrome Patients
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Jorge, Joana; Marques, Bárbara; Paiva, Artur; Oliveiros, Bárbara; et al, Frontiers in Cell and Developmental Biology. 9. 2021. http://dx.doi.org/10.3389/fcell.2021.701328 . 10.3389/fcell.2021.701328 . published Frontiers in Cell and Developmental Biology
Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: From Molecular Mechanisms to Clinical Relevance
Alves, Raquel; Gonçalves, Ana Cristina; Rutella, Sergio; Almeida, António M.; De Las Rivas, Javier; Trougakos, Ioannis P.; Sarmento Ribeiro, Ana Bela, Cancers. 19. 13. 2021. http://dx.doi.org/10.3390/cancers13194820 . 10.3390/cancers13194820 . published Cancers
DNA Methylation Is Correlated with Oxidative Stress in Myelodysplastic Syndrome—Relevance as Complementary Prognostic Biomarkers
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Marques, Bárbara; Oliveiros, Bárbara; Pereira, Amélia; Nascimento Costa, José Manuel; et al, Cancers. 13. 13. 2021. http://dx.doi.org/10.3390/cancers13133138 . 10.3390/cancers13133138 . published Cancers
Acute myeloid leukemia sensitivity to metabolic inhibitors: glycolysis showed to be a better therapeutic target
Lapa, Beatriz; Gonçalves, Ana Cristina; Jorge, Joana; Alves, Raquel; Pires, Ana Salomé; Abrantes, Ana Margarida; Coucelo, Margarida; et al, Medical Oncology. 8. 37. 2020. http://dx.doi.org/10.1007/s12032-020-01394-6 . 10.1007/s12032-020-01394-6 . published Medical Oncology
Flow cytometry and targeted immune transcriptomics identify distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interferon-a
Alves, Raquel; McArdle, Stephanie E. B.; Vadakekolathu, Jayakumar; Gonçalves, Ana Cristina; Freitas-Tavares, Paulo; Pereira, Amélia; Almeida, Antonio M.; Sarmento-Ribeiro, Ana Bela; Rutella, Sergio, Journal of Translational Medicine. 1. 18. 2020. http://dx.doi.org/10.1186/s12967-019-02194-x . 10.1186/s12967-019-02194-x . published Journal of Translational Medicine
MicroRNA signature refine response prediction in CML
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Marques, Gilberto; Luís, D.; Barbosa-Ribeiro, André; Freitas-Tavares, Paulo; et al, Scientific Reports. 1. 9. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068470311&partnerID=MN8TOARS . 10.1038/s41598-019-46132-9 . published Scientific Reports
Everolimus in combination with Imatinib overcomes resistance in Chronic myeloid leukaemia
Alves, Raquel; Gonçalves, Ana Cristina; Jorge, Joana; Alves, Joana; Alves da Silva, António; Freitas-Tavares, Paulo; Nascimento-Costa, José Manuel; Almeida, António; Sarmento-Ribeiro, Ana Bela, Medical Oncology. 3. 36. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061978734&partnerID=MN8TOARS . 10.1007/s12032-019-1253-5 . published Medical Oncology
Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines
Jorge, Joana; Petronilho, Sara; Alves, Raquel; Coucelo, Margarida; Gonçalves, Ana Cristina; Nascimento-Costa, José Manuel; Sarmento-Ribeiro, Ana Bela, Investigational New Drugs. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85066463071&partnerID=MN8TOARS . 10.1007/s10637-019-00796-2 . published Investigational New Drugs
Tissular growth factors profile after teduglutide administration on an animal model of intestinal anastomosis,Perfil tisular de factores de crecimiento postadministración de teduglutida en un modelo animal de anastomosis intestinal
da Costa, Beatriz; Gonçalves, Ana Cristina; Abrantes, Ana Margarida; Alves, Raquel; Matafome, Paulo; Sarmento-Ribeiro, Ana Bela; Botelho, Maria Filomena; Castro-Sousa, Francisco, Nutricion Hospitalaria. 185 - 193. 1. 35. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044216245&partnerID=MN8TOARS . 10.20960/nh.1326 . published Nutricion Hospitalaria
Intestinal Epithelial Stem Cells: Distinct Behavior After Surgical Injury and Teduglutide Administration
Costa, Beatriz P.; Gonçalves, Ana C.; Abrantes, Ana M.; Alves, Raquel; Matafome, Paulo; Seiça, Raquel; Sarmento-Ribeiro, Ana B.; Botelho, M. Filomena; Castro-Sousa, Francisco, Journal of Investigative Surgery. online. 2017. 10.1080/08941939.2017.1294217 . published Journal of Investigative Surgery
Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Cortesão, Emília; Carda, José Pedro; Branco, Claudia C.; Oliveiros, B.; et al, Molecular Carcinogenesis. 130 - 148. 1. 56. 2016. http://onlinelibrary.wiley.com/doi/10.1002/mc.22478/full . 10.1002/mc.22478 . published Molecular Carcinogenesis
Drug transporters play a key role in the complex process of Imatinib resistance in vitro
Alves, Raquel; Fonseca, Ana Raquel; Goncalves, Ana C.; Ferreira-Teixeira, Margarida; Lima, Joana; Abrantes, Ana M.; Alves, Vera; et al, Leukemia Research. 355 - 360. 3. 39. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000349957800016&KeyUID=WOS:000349957800016 . 10.1016/j.leukres.2014.12.008 . published Leukemia Research
Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves
Liberal, Joana; Costa, Gustavo; Carmo, Anália; Vitorino, Rui; Marques, Carla; Domingues, Maria Rosário; Domingues, Pedro; et al, Arabian Journal of Chemistry. 1 - 15. Online. 2015. 10.1016/j.arabjc.2015.11.014 . published Arabian Journal of Chemistry
Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma
Mamede, Ana; Guerra, S.; Laranjo, Mafalda; Carvalho, Maria João; Oliveira, R.C.; Gonçalves, Ana Cristina; Alves, Raquel; et al, Medical Oncology. 257 - 257. 12. 32. 2015. http://link.springer.com/article/10.1007%2Fs12032-015-0702-z . 10.1007/s12032-015-0702-z . published Medical Oncology
L744,832 and Everolimus Induce Cytotoxic and Cytostatic Effects in Non-Hodgkin Lymphoma Cells
Mendes, José; Gonçalves, Ana Cristina; Alves, Raquel; Jorge, Joana; Pires, Ana; Ribeiro, A.; Sarmento-Ribeiro, Ana Bela, Pathology & Oncology Research. 301 - 309. 2. 22. 2015. 10.1007/s12253-015-9998-4 . published Pathology & Oncology Research
5 29 out of 29 Publications
All projects
Information of exclusive responsibility of the researcher 02-03-2025 , from platform CIÊNCIAVITAE.
2025 -
Interrogation of the immune-microenvironment of T-cell malignancies
ImmuneT-ME
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Comissão de Coordenação e Desenvolvimento Regional do Centro
2024 -
Relevance of NF-kB and NRF2/KEAP1 pathways as biomarkers of drug response in patients with Multiple Myeloma
LPCC/GSK
Principal investigator
Funders: Liga Portuguesa Contra o Cancro; GlaxoSmithKline Produtos Farmacêuticos Lda
2023 -
Relevância clínica das plaquetas como biomarcadores não invasivos no Mieloma Múltiplo - Um estudo piloto
APCL 2023
Researcher
Associação Portuguesa Contra a Leucemia; Sociedade Portuguesa de Hematologia; Amgen Biofarmaceutica Lda
2023 -
Clinical Relevance of non-invasive biomarkers in bone and soft tissue tumors
NRC-LPCC/CIMAGO 2023
Researcher
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2023 -
Circular RNAs in hematological neoplasms: Potential biomarker from diagnosis to therapy
NRC-LPCC/CIMAGO 2023
Principal investigator
Liga Portuguesa Contra o Cancro Núcleo Regional do Centro
2022 -
Crosstalk Between Mutation Landscape, Immune Dysregulation And Microbiome - Role In Pathogenesis And Progression Of Myeloproliferative Neoplasms
01/23
Researcher
Sociedade Portuguesa de Hematologia
2022 -
Molecular therapeutic targets in IDH1/2 mutant AML: exploring the links between metabolism and DNA
02/23
Researcher
Sociedade Portuguesa de Hematologia
2022 -
HemaCirc: circular RNAs as an innovative tool in hematological neoplasms
CIMAGO 08/22
Principal investigator
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2022 -
The role of platelets in diagnosis, prognosis and therapeutic monitoring in diffuse large B-cell lymphoma
CIMAGO 06/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2022 -
Evaluation of molecular mechanisms of resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma
CIMAGO 05/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2022 -
Synthetic lethality in acute myeloid leukemia - Role of DNA damage response
CIMAGO 04/22
Researcher
Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2021/01/01 - 2025/12/31
Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2019 -
EPO-EPOR axis in MDS - Clinical relevance as prognostic and drug response biomarker
Project 02/19
Researcher
Funders: Sociedade de Portuguesa de Hematologia
2019 -
Red Transfronteriza de Innovación en Diagnóstico Precoz de Leucemia para un envejecimiento saludable (IDIAL-NET )
IDIAL-NET
Researcher
2018 -
NRF2-KEAP1 axis as a new potential prognostic biomarker in chronic lymphocytic leukemia
Project 03/18
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2018 -
Epigenetic in Chronic Lymphocytic Leukemia B – Impact in prognosis and therapy
Project 02/18
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2018 -
Identification of new response markers to Bortezomib and Lenalidomide in patients with multiple myeloma – The role of NF-kB and NRF2/KEAP1
Project 04/18
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Liga Portuguesa Contra o Cancro; Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2016 - 2018
The role of microRNAs for chronic myeloid leukemia therapeutic selection
Project FMUC-BST-2016-214
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Universidade de Coimbra Faculdade de Medicina; Banco Santander Totta
2014 - 2018
The role of MicroRNAs for therapeutic selection in BCR-ABL+ Leukemias
Project 10/14
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2015
Avaliação da relação entre o stress oxidativo e modulação epigenética em neoplasias hematológicas - Papel da variabilidade genética/epigenética no risco de desenvolver neoplasias hematológicas e/ou resistência ao tratamento
Project 22/09
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2015
Alterações celulares e moleculares no Mieloma Múltiplo – Implicações clínicas e terapêuticas
Project 23/09
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2014
Caracterização clínica e molecular da síndrome mielodisplásica - papel da apoptose e dos microRNAs no prognóstico e terapêutica
Project 24/09
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2013
The cross-talk between oxidative stress and epigenetics – A possible route in myeloid leukaemia
Project GAI-FMUC
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Universidade de Coimbra Faculdade de Medicina; Banco Santander Totta
2012 - 2020
Characterization of Cellular and Molecular mechanisms involved in Sensitivity and Resistance to BCR-ABL targeted therapies in Chronic Myelogenous
Project 18/12
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2012 - 2019
Modulação redox em neoplasias hematológicas – o NRF2 como novo marcador e alvo terapêutico
Project 10/12
Researcher
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
5 25 out of 25 projects
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