Jessica Da Silva

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PhD Student

Obesity, Diabetes and Complications

Neuronal Circuits and Behavior

E-mail
jessicasilva@cnc.uc.pt
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Jessica Gonçalves Da Silva is actually attending the PhD Programme in Experimental Biology and Biomedicine (PDBEB) 2020/2021 from the Institute for Interdisciplinary Research of the University of Coimbra with a FCT individual PhD scholarship. She also integrated the Fulbright community having be awarded a Fulbright scholarship for research with the support of FCT. She completed her Master Degree in Pharmaceutical Biotechnology in 2019 (Faculty of Pharmacy, University of Coimbra), with a dissertation entitled "Evaluation of the immunotoxicological properties of PLA nanoparticles", and her Bachelor Degree in Biomedical Sciences in 2017 (Department of Medical Sciences, University of Aveiro). Moreover, she is currently a researcher at CNC.IBILI (CIBB, University of Coimbra), being a laboratory member of the Metabolism, Aging and Disease - Obesity, Diabetes and Complications Group. She has published an original article as co-author in the journal Chemical Research in Toxicology (Quartile 1) entitled "Unravelling the immunotoxicity of polycaprolactone nanoparticles - effects of polymer molecular weight, hydrolysis and blends", and another original article as first author in the journal Frontiers in Bioengineering and Biotechnology (Quartile 2) entitled " Poly(D,L-Lactic Acid) Nanoparticle Size Reduction Increases Its Immunotoxicity". In her professional activities, she interacted with 9 collaborator(s) co-authorship of scientific papers. Moreover, she has been accredited as investigator for scientific experimentation involving animals (rats and mice) attributed by DGAV (Direção Geral de Alimentação e Veterinária, Portugal) - Course on Laboratory Animal Sciences - FELASA Category B certification. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: polymeric nanoparticles; polylactic acid (PLA); polycaprolactone (PCL); chitosan (CHI); safety-by-design; quality-by-design; in vitro; in vivo; immunotoxicity; immune cells; inflammatory markers; gene expression; metabolism; diabetes; insulin resistance; insulin signaling; diabetes complications; diabetic foot ulcerations; wound healing; biomarker levels.

Affiliation

University of Coimbra, Institute for Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), Portugal; CNC - Center for neuroscience and Cell Biology, University of Coimbra, Portugal.

Publications

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Information about journal articles, updated at 22-12-2024, from platform CIÊNCIAVITAE.

Impact of Psychological Distress on Physiological Indicators of Healing Prognosis in Patients with Chronic Diabetic Foot Ulcers: A Longitudinal Study

Da Silva, Jessica; Santos, Diana; Vilaça, Margarida; Carvalho, André; Carvalho, Rui; Jesus Dantas, Maria de; Pereira, M. Graça; Carvalho, Eugénia, Advances in Wound Care. 2023. http://dx.doi.org/10.1089/wound.2023.0043 . 10.1089/wound.2023.0043 . Advances in Wound Care

Healing profiles in patients with a chronic diabetic foot ulcer: An exploratory study with machine learning

Pereira, M. Graça; Vilaça, Margarida; Braga, Diogo; Madureira, Ana; Da Silva, J.; Santos, Diana; Carvalho, Eugénia, Wound Repair and Regeneration. 793 - 803. 6. 31. 2023. 10.1111/wrr.13141 . Wound Repair and Regeneration

Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers

Da Silva, Jessica; Leal, Ermelindo C.; Carvalho, Eugénia; Silva, Eduardo A., International Journal of Molecular Sciences. 12. 24. 2023. http://dx.doi.org/10.3390/ijms24129900 . 10.3390/ijms24129900 . published International Journal of Molecular Sciences

Bioactive Antimicrobial Peptides as Therapeutic Agents for Infected Diabetic Foot Ulcers

Da Silva, J.; Leal, Ermelindo C; Carvalho, Eugenia, Biomolecules. 2021. https://doi.org/10.3390/biom11121894 . 10.3390/biom11121894 . published Biomolecules

Unravelling the Immunotoxicity of Polycaprolactone Nanoparticles - Effects of Polymer Molecular Weight, Hydrolysis, and Blends

Jesus, Sandra; Bernardi, Natalia; Da Silva, Jessica; Colaço, Mariana; Panão Costa, João; Fonte, Pedro; Borges, Olga, Chemical Research in Toxicology. 2020. http://dx.doi.org/10.1021/acs.chemrestox.0c00208 . 10.1021/acs.chemrestox.0c00208 . published Chemical Research in Toxicology

5 6 out of 6 Publications

All projects

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Information of exclusive responsibility of the researcher 22-12-2024 , from platform CIÊNCIAVITAE.

2019/12/01 - 2020/08/31

HealthyAging 2020

HEALTHYAGING 2020 (CENTRO-01- 0145-FEDER-000012)

Master Student Fellow

CNC.IBILI

Funders: European Regional Development Fund

2018/12 - 2019/07

Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions

ProSafe JTC/0001/2016

Researcher

CNC.IBILI

Funders: Fundação para a Ciência e a Tecnologia

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