João David Panão da Costa

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Publications

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Information about journal articles, updated at 17-11-2024, from platform CIÊNCIAVITAE.

Curcumin-encapsulated glucan nanoparticles as an oxidative stress modulator against human hepatic cancer cells

Roquito, Tiago; Colaço, Mariana; Panão Costa, João; Borges, Olga, Colloids and Surfaces B: Biointerfaces. 245. 2025. http://dx.doi.org/10.1016/j.colsurfb.2024.114326 . 10.1016/j.colsurfb.2024.114326 . published Colloids and Surfaces B: Biointerfaces

Insights into Immune Exhaustion in Chronic Hepatitis B: A Review of Checkpoint Receptor Expression

Panão Costa, João; de Carvalho, Armando; Paiva, Artur; Borges, Olga, Pharmaceuticals. 7. 17. 2024. http://dx.doi.org/10.3390/ph17070964 . 10.3390/ph17070964 . Pharmaceuticals

Exploring the immunomodulatory properties of glucan particles in human primary cells

Panão Costa, João; Jesus, Sandra; Colaço, Mariana; Lebre, Filipa; Mateus, Daniela; Sebastião, Ana Isabel; Cruz, Maria Teresa; Alfaro-Moreno, Ernesto; Borges, Olga, International Journal of Pharmaceutics. 123996. 655. 2024. https://www.sciencedirect.com/science/article/pii/S0378517324002308?via%3Dihub . published International Journal of Pharmaceutics

The Effect of Curcumin-Loaded Glucan Nanoparticles on Immune Cells: Size as a Critical Quality Attribute

Colaço, Mariana; Roquito, Tiago; Panão Costa, João; Cruz, Maria Teresa; Borges, Olga, Pharmaceutics. 2. 15. 2023. http://dx.doi.org/10.3390/pharmaceutics15020623 . 10.3390/pharmaceutics15020623 . published Pharmaceutics

Endotoxin contamination of nanoparticle formulations: A concern in vaccine adjuvant mechanistic studies.

Panão Costa, João; Jesus, Sandra; Colaço, Mariana; Duarte, Alana; Soares, Edna; Borges, Olga, Vaccine. 3481 - 3485. 23. 41. 2023. https://doi.org/10.1016/j.vaccine.2023.04.063 . published Vaccine

Unravelling the Immunotoxicity of Polycaprolactone Nanoparticles—Effects of Polymer Molecular Weight, Hydrolysis, and Blends

Jesus, Sandra; Bernardi, Natalia; da Silva, Jessica; Colaço, Mariana; Panão Costa, João; Fonte, Pedro; Borges, Olga, Chemical Research in Toxicology. 2819 - 2833. 11. 33. 2020. published Chemical Research in Toxicology

Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility

Jesus, Sandra; Marques, Ana Patrícia; Duarte, Alana; Soares, Edna; Costa, João Panão; Colaço, Mariana; Schmutz, Mélanie; et al, Frontiers in Bioengineering and Biotechnology. 8. 2020. http://dx.doi.org/10.3389/fbioe.2020.00100 . 10.3389/fbioe.2020.00100 . published Frontiers in Bioengineering and Biotechnology

Optimization of Chitosan-a-casein Nanoparticles for Improved Gene Delivery: Characterization, Stability, and Transfection Efficiency

Panão Costa, João; Carvalho, Sofia; Jesus, Sandra; Soares, Edna; Marques, Ana Patrícia; Borges, Olga, AAPS PharmSciTech. 3. 20. 2019. http://dx.doi.org/10.1208/s12249-019-1342-y . 10.1208/s12249-019-1342-y . published AAPS PharmSciTech

Immune response elicited by an intranasally delivered HBsAg low-dose adsorbed to poly-e-caprolactone based nanoparticles

Jesus, Sandra; Soares, Edna; Costa, João; Borchard, Gerrit; Borges, Olga, International Journal of Pharmaceutics. 59 - 69. 1-2. 504. 2016. http://dx.doi.org/10.1016/j.ijpharm.2016.03.013 . 10.1016/j.ijpharm.2016.03.013 . published International Journal of Pharmaceutics

All projects

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Information of exclusive responsibility of the researcher 17-11-2024 , from platform CIÊNCIAVITAE.

2023/07/19 - 2025/12/31

CInTech: Technological Hub for Innovation, Translation and Industrialization of Complex Injectable Drugs

7131

Researcher

CNC.IBILI; Bluepharma; Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

2021/10/10 - 2022/12/31

Vacina Intranasal genética contra o COVID: estudos de imunização em murganhos

13824

Researcher

Funders: Gilead Sciences Lda

2018 - 2021

Hepatitis B therapeutic vaccine: Production of glucan-based particles towards selective delivery hepatitis B antigens to immune cells to induce antiviral activity - POCI-01-0145-FEDER-030331

POCI-01-0145-FEDER-030331

Researcher

2018/04 - 2019/12

Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions - ProSafe JTC/0001/2016

ProSafe JTC/0001/2016

Master Student Fellow

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