Publications
Information about journal articles, updated at 15-06-2025, from platform CIÊNCIAVITAE.
A systematic screening assay identifies efficient small guide RNAs for CRISPR activation
Arvidsson, Elin; Lobo, Diana Duarte; Sabarese, Ermelinda; Duarte, Fabio; Nobre, Rui Jorge; Quintino, Luis; Lundberg, Cecilia, Frontiers in Bioengineering and Biotechnology. 13. 2025. https://doi.org/10.3389/fbioe.2025.1336313 . 10.3389/fbioe.2025.1336313 . Frontiers in Bioengineering and Biotechnology
Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol
Lopes, Miguel M.; Lopes, Sara M.; Baganha, Rafael; Henriques, Carina; Silva, Ana C.; Lobo, Diana Duarte; Cortes, Luísa; de Almeida, Luís Pereira; Nobre, Rui Jorge, Journal of Visualized Experiments. 206. 2024. https://doi.org/10.3791/66550 . 10.3791/66550 . Journal of Visualized Experiments
Viral-based animal models in polyglutamine disorders
Carina Henriques; Miguel M Lopes; Ana C Silva; Diana D Lobo; Romina Aron Badin; Philippe Hantraye; Luís Pereira de Almeida; Rui Jorge Nobre, Brain. 2024. https://doi.org/10.1093/brain/awae012 . 10.1093/brain/awae012 . Brain
Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3
Rufino-Ramos, David; Albuquerque, Patrícia R.; Leandro, Kevin; Carmona, Vitor; Martins, Inês M.; Fernandes, Rita; Henriques, Carina; et al, Molecular Therapy. 1275 - 1292. 5. 31. 2023. http://dx.doi.org/10.1016/j.ymthe.2023.04.001 . 10.1016/j.ymthe.2023.04.001 . Molecular Therapy
miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3
Nobre, Rui Jorge; Diana D. Lobo; Carina Henriques; Sonia P. Duarte; Sara M. Lopes; Ana C. Silva; Miguel M. Lopes; et al, Nucleic Acid Therapeutics. 2022. https://doi.org/10.1089/nat.2021.0020 . 10.1089/nat.2021.0020 . Nucleic Acid Therapeutics
ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease
Vasconcelos-Ferreira, Ana; Martins, Inês Morgado; Lobo, Diana; Pereira, Dina; Lopes, Miguel M.; Faro, Rosário; Lopes, Sara M.; et al, Molecular Therapy. 2021. http://dx.doi.org/10.1016/j.ymthe.2021.07.012 . 10.1016/j.ymthe.2021.07.012 . published Molecular Therapy
The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples
Duarte Lobo, Diana; Nobre, Rui Jorge; Oliveira Miranda, Catarina; Pereira, Dina; Castelhano, João; Sereno, José; Koeppen, Arnulf; Castelo-Branco, Miguel; Pereira de Almeida, Luís, Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-00955-0 . 10.1186/s40478-020-00955-0 . published Acta Neuropathologica Communications
Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders
Silva, Ana C; Lobo, Diana D; Martins, Inês M; Lopes, Sara M; Henriques, Carina; Duarte, Sónia P; Dodart, Jean-Cosme; Nobre, Rui Jorge; Pereira de Almeida, Luis, Brain. 407 - 429. 2. 143. 2019. http://dx.doi.org/10.1093/brain/awz328 . 10.1093/brain/awz328 . Brain
5 8 out of 8 Publications
