Publications

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Information about journal articles, updated at 22-12-2024, from platform CIÊNCIAVITAE.

Optimization of Platelet-Rich Plasma Preparation for Regenerative Medicine: Comparison of Different Anticoagulants and Resuspension Media

Alexandra Carvalho; Ana Filipa Ferreira; Maria Soares; Susana Santos; Patrícia Tomé; Juliana Machado-Simões; Ana Sofia Pais; et al, Bioengineering. 2024. http://dx.doi.org/10.3390/bioengineering11030209 . 10.3390/bioengineering11030209 . Bioengineering

Low responders may benefit from undergoing ovarian stimulation with a long GnRH agonist protocol with corifollitropin alfa followed by hMG.

Ferreira AF; Pais AS; Sousa AP; Cortesão P; Almeida-Santos T, JBRA assisted reproduction. 2023. http://europepmc.org/abstract/med/37257074 . 10.5935/1518-0557.20230001 . JBRA assisted reproduction

New Insights on Sperm Function in Male Infertility of Unknown Origin: A Multimodal Approach

Rita I. Pacheco; Maria I. Cristo; Sandra Anjo; Silva, Andreia F; Maria Inês Sousa; Renata S. Tavares; Ana Paula Sousa; et al, Biomolecules. 2023. https://www.mdpi.com/2218-273X/13/10/1462 . 10.3390/biom13101462 . Biomolecules

Association Between Follicle-Stimulating Hormone Receptor (FSHR) rs6166 and Estrogen Receptor 1 (ESR1) rs2234693 Polymorphisms and Polycystic Ovary Syndrome Risk, Phenotype, and Reproductive Outcomes in an Infertile Portuguese Population

Inês H Vieira; Alexandra F Carvalho; Sandra Almeida Reis; Ana L Carreira; Conceição Dias; Silvana Fernandes; Ana Filipa Ferreira; et al, Cureus. 2023. http://dx.doi.org/10.7759/cureus.35690 . 10.7759/cureus.35690 . Cureus

Aging and oocyte competence: A molecular cell perspective

Ana Filipa Ferreira; Maria Soares; Teresa Almeida-Santos; João Ramalho-Santos; Ana Paula Sousa, WIREs Mechanisms of Disease. 2023. https://doi.org/10.1002/wsbm.1613 . 10.1002/wsbm.1613 . WIREs Mechanisms of Disease

Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus Ultracentrifugation

Maria Soares; Maria M. Pinto; Rui Jorge Nobre; Luís Pereira de Almeida; Maria da Graça Rasteiro; Teresa Almeida-Santos; João Ramalho-Santos; Ana Paula Sousa, Biomolecules. 2023. https://doi.org/10.3390/biom13020278 . 10.3390/biom13020278 . Biomolecules

Spatiotemporal dynamics of SIRT 1, 2 and 3 during in vitro maturation of bovine oocytes

Ana Filipa Ferreira; Juliana Machado-Simões; Maria Soares; Ana Paula Sousa; João Ramalho-Santos; Teresa Almeida-Santos, Theriogenology. 60 - 69. 186. 2022. http://dx.doi.org/10.1016/j.theriogenology.2022.04.004 . 10.1016/j.theriogenology.2022.04.004 . Theriogenology

PROTEOMIC APPROACH TO THE CHARACTERIZATION OF UNKNOWN ORIGIN MALE INFERTILITY

Pacheco; Ana Paula Sousa; Moura-Ramos, European Journal of Clinical Investigation. 61 - 61. S1. 52. 2022. http://dx.doi.org/10.1111/eci.13796 . 10.1111/eci.13796 . published European Journal of Clinical Investigation

It Takes Two to Tango: the Involvement of Certain Environmental Endocrine-Disrupting Chemicals in MaleInfertility Aetiology

Tavares RS; Ana Paula Sousa; Almeida-Santos T, Ramalho-Santos J, European Journal of Clinical Investigation. 176 - 176. S1. 52. 2022. http://dx.doi.org/10.1111/eci.13796 . 10.1111/eci.13796 . published European Journal of Clinical Investigation

Fertility preservation in women with haematological malignancies

Rafael Ferro; Ana Sofia Pais; Ana Paula Sousa; Teresa Almeida Santos, Human Fertility. 2022. https://doi.org/10.1080/14647273.2022.2042605 . 10.1080/14647273.2022.2042605 . Human Fertility

Using Data Mining to Assist in Predicting Reproductive Outcomes Following Varicocele Embolization.

Sousa AP; Santos-Pereira J; Freire MJ; Parada B; Almeida-Santos T; Bernardino J; Ramalho-Santos J, Journal of clinical medicine. 2021. http://europepmc.org/abstract/med/34441799 . 10.3390/jcm10163503 . Journal of clinical medicine

Comparative <i>in vitro</i> study on the local tolerance and efficacy of benzalkonium chloride, myristalkonium chloride and nonoxynol-9 as active principles in vaginal contraceptives

Alfaiate, Maria Inês; António Santos, Rita; Silva, Andreia Filipa; Sousa, Ana Paula; Almeida-Santos, Teresa; Gendron, Célia; Jabbour, Violaine; et al, The European Journal of Contraception &amp; Reproductive Health Care. 334 - 342. 4. 26. 2021. http://dx.doi.org/10.1080/13625187.2021.1900563 . 10.1080/13625187.2021.1900563 . The European Journal of Contraception &amp; Reproductive Health Care

Does supplementation with mitochondria improve oocyte competence? A systematic review.

Filipa Ferreira; Maria Soares; Sandra Almeida Reis; Joao Ramalho-Santos; Ana Paula Sousa; Teresa Almeida-Santos, Reproduction. 269 - 287. 161. 2021. https://doi.org/10.1530/REP -20-0351 . 10.1530/rep-20-0351 . published Reproduction

Fluorescent probes for the detection of reactive oxygen species in human spermatozoa.

Escada-Rebelo S; Mora FG; Ana Paula Sousa; Almeida-Santos T; Paiva A; Ramalho-Santos J, Asian journal of andrology. 2020. http://europepmc.org/abstract/med/31939350 . 10.4103/aja.aja_132_19 . published Asian journal of andrology

Aging-related bioenergetic alterations in bovine oocytes

Maria M Soares; Ana Paula Sousa; Raquel D Fernandes; Ana Filipa Ferreira; Teresa Almeida-Santos; João Ramalho-Santos, Theriogenology. 2020. 10.1016/j.theriogenology.2020.07.036 . published Theriogenology

Adverse effect of higher waist circumference in assisted reproductive technology outcomes

Ana Filipa Rodrigues Ferreira; Ana Paula Sousa; Mariana Moura-Ramos; Paulo Cortesao; Ana Luisa Costa; Teresa Almeida-Santos, European Gynecology & Obstetrics. 2020. https://doi.org/10.53260/ego.202017 . 10.53260/ego.202017 . European Gynecology & Obstetrics

In vitro safety and efficacy of Pharmatex® formulations and Nonoxinol 9 as local contraceptives: a comparative study

Toxicology and Applied Pharmacology. 2020. Toxicology and Applied Pharmacology

Fertility preservation with successful pregnancy outcome in a patient with transplanted heart and non-Hodgkin's lymphoma-a case report

Pais, A.S.; Guerra, N.; Couto, D.; Sousa, A.P.; Almeida-Santos, T., BMC Pregnancy and Childbirth. 1. 19. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075294431&partnerID=MN8TOARS . 10.1186/s12884-019-2587-x . BMC Pregnancy and Childbirth

Medically assisted reproduction in natural cycle: Outcome evaluation of a reproductive medicine department,Procriação medicamente assistida em ciclo natural: Avaliação dos resultados de um departamento de medicina da reprodução

Alves, M.C.; Marques, A.L.; Leite, H.B.; Sousa, A.P.; Almeida-Santos, T., Acta Medica Portuguesa. 25 - 29. 1. 32. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061491840&partnerID=MN8TOARS . 10.20344/amp.10195 . Acta Medica Portuguesa

Alzheimer’s disease-related amyloid-ß<inf>1–42</inf> peptide induces the loss of human sperm function

Tavares, R.S.; Martins, S.; Almeida-Santos, T.; Sousa, A.P.; Ramalho-Santos, J.; da Cruz e Silva, O.A., Cell and Tissue Research. 647 - 651. 3. 369. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026841709&partnerID=MN8TOARS . 10.1007/s00441-017-2665-1 . Cell and Tissue Research

Embolization of clinical varicocele: Long term effects on semen quality, complication rates and satisfaction

M.J. Freire; A.P. Sousa; L. Sousa; J. Ramalho-Santos; B. Parada; T. Almeida-Santos; A. Figueiredo, European Urology Supplements. e781 - e781. 3. 16. 2017. https://doi.org/10.1016%2Fs1569-9056%2817%2930511-0 . 10.1016/s1569-9056(17)30511-0 . European Urology Supplements

Eficácia da vibroestimulação peniana após lesão vertebromedular

Sandra de Oliveira; António Azenha; Ana Paula Sousa; João Páscoa Pinheiro; Ana Teresa Almeida Santos, Acta Urológica Portuguesa. 16 - 21. 1. 33. 2016. https://doi.org/10.1016%2Fj.acup.2016.01.002 . 10.1016/j.acup.2016.01.002 . Acta Urológica Portuguesa

Relation of cumulus cell status with single oocyte maturity, fertilization capability and patient age.

Lourenço B; Sousa AP; Almeida-Santos T; Ramalho-Santos J; Lourenço, B.; Sousa, A.P.; Almeida-Santos, T.; Ramalho-Santos, J., Journal of Reproduction and Infertility. 15 - 21. 1. 15. 2014. http://europepmc.org/abstract/med/24696155 . Journal of Reproduction and Infertility

Low amounts of mitochondrial reactive oxygen species define human sperm quality.

Marques M; Sousa AP; Paiva A; Almeida-Santos T; Ramalho-Santos J; Marques, M.; Sousa, A.P.; et al, Reproduction. 817 - 824. 6. 147. 2014. http://europepmc.org/abstract/med/24534950 . 10.1530/rep-13-0644 . Reproduction

Female (in)fertility

Saad, H.; Khalil, E.; Bora, S. A.; Parikh, J.; Abdalla, H.; Thum, M. Y.; Bina, V.; et al, Human Reproduction. i229 - i247. suppl 1. 28. 2013. http://dx.doi.org/10.1093/humrep/det213 . 10.1093/humrep/det213 . Human Reproduction

Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following in vitro fertilization

Tavares, R.S.; Silva, A.F.; Lourenço, B.; Almeida-Santos, T.; Sousa, A.P.; Ramalho-Santos, J., Andrology. 830 - 837. 6. 1. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886438897&partnerID=MN8TOARS . 10.1111/j.2047-2927.2013.00127.x . Andrology

Anterior positioning of sex chromosomes on the head of human sperm sorted using visible wavelengths

Alçada-Morais, Sofia; Sousa, Ana Paula; Paiva, Artur; Almeida-Santos, Teresa; Ramalho-Santos, João, Systems Biology in Reproductive Medicine. 223 - 226. 4. 59. 2013. http://dx.doi.org/10.3109/19396368.2013.787129 . 10.3109/19396368.2013.787129 . accepted Systems Biology in Reproductive Medicine

Exogenous glucose improves long-standing human sperm motility, viability, and mitochondrial function.

Amaral A; Paiva C; Baptista M; Sousa AP; Ramalho-Santos J, 2011. http://europepmc.org/abstract/med/21839434 . 10.1016/j.fertnstert.2011.07.1091 .

Not all sperm are equal: functional mitochondria characterize a subpopulation of human sperm with better fertilization potential.

Sousa AP; Amaral A; Baptista M; Tavares R; Caballero Campo P; Caballero Peregrín P; Freitas A; et al, 2011. http://europepmc.org/abstract/med/21448461 . 10.1371/journal.pone.0018112 .

Session 04: Novel Techniques for Sperm Selection

Figueiredo, S.; Sousa, A. P.; Parada, B.; Carvalheiro, V.; Almeida Santos, T.; Obejero, E. Y.; De Caro, R.; et al, Human Reproduction. i6 - i9. Supplement. 25. 2010. http://dx.doi.org/10.1093/humrep/de.25.s1.4 . 10.1093/humrep/de.25.s1.4 . Human Reproduction

Mitochondrial functionality in reproduction: from gonads and gametes to embryos and embryonic stem cells.

Ramalho-Santos J; Varum S; Amaral S; Mota PC; Sousa AP; Amaral A, 2009. http://europepmc.org/abstract/med/19414527 . 10.1093/humupd/dmp016 .

Dual use of Diff-Quik-like stains for the simultaneous evaluation of human sperm morphology and chromatin status.

Sousa AP; Tavares RS; Velez de la Calle JF; Figueiredo H; Almeida V; Almeida-Santos T; Ramalho-Santos J, 2009. http://europepmc.org/abstract/med/18835873 . 10.1093/humrep/den365 .

Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markers.

Varum S; Bento C; Sousa AP; Gomes-Santos CS; Henriques P; Almeida-Santos T; Teodósio C; Paiva A; Ramalho-Santos J, 2007. http://europepmc.org/abstract/med/17118365 . 10.1016/j.fertnstert.2006.07.1528 .

Localization of SNAREs., NSF and Caveolin 1 in human spermatozoa: Relationship with seminal parameters

Sousa, A.P.M.; Gomes-Santos, C.S.S.; Ramalho-Santos, J., Systems Biology in Reproductive Medicine. 347 - 353. 5. 52. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961202390&partnerID=MN8TOARS . 10.1080/01485010600667050 . Systems Biology in Reproductive Medicine

Teaching about citric acid cycle using plant mitochondrial preparations: Some assays for use in laboratory courses*.

Vicente JA; Gomes-Santos CS; Sousa AP; Madeira VM, 2005. http://europepmc.org/abstract/med/21638559 . 10.1002/bmb.2005.494033022444 .

All projects

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Information of exclusive responsibility of the researcher 22-12-2024 , from platform CIÊNCIAVITAE.

2022/01/01 - 2024/06/30

OOCYTE AGING: EVALUATION OF MITOCHONDRIAL FUNCTION AND DEVELOPMENT OF REJUVENATING STRATEGIES

FERTIMPROVE - IT0230

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Merck SA

2021/01/01 - 2025/12/31

Center for Innovative Biomedicine and Biotechnology - Associate Laboratory

LA/P/0058/2020

Universidade de Coimbra; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2020/10/01 - 2022/04/01

Reproduction@Estarreja: is female reproductive potential at risk?"

s/codigo

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: LabEX - Dispositif de Recherche Interdisciplinaire sur les Interactions Hommes-Milieux

2019/10/01 - 2020/10/01

Men’s Health Estarreja – Evaluation of the reproductive health of men living in a heavily industrialized area

OHM-E/2019/Proj.3

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: LabEX - Dispositif de Recherche Interdisciplinaire sur les Interactions Hommes-Milieux

2019/01/01 - 2019/12/31

CNC. IBILI

UID/NEU/04539/2019

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2018/06/01 - 2021/05/31

O estado pausado: um método inovador para bioengenharia de Células Estaminais

PTDC/BTM-SAL/28871/2017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018/05/16 - 2020/01/01

HEALTHYAGING 2020

CENTRO-01-0145-FEDER-000012

Funders: Fundação para a Ciência e a Tecnologia

2018/07/06 - 2021/07/05

Pesquisa de novos biomarcadores para a infertilidade masculina de origem desconhecida

PTDC/MEC-AND/28599/2017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2017/01/01 - 2020/12/31

Preservation of Reproductive Potential in Oncological Patients: Angiogenesis Stimulation of Cryopreserved Ovarian Tissue Graft

CSD006003#IV0337

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Merck SA

2012/05/06 - 2015/08/31

Role of the pyruvate dehydrogenase kinase metabolic switch in pluripotency: insights into cancer and stem cell biology.

PTDC/QUI-BIQ/120652/2010

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012/05/01 - 2015/09/30

New strategies to recover fertility and genetic variability of endangered felids: development of xenografting and spermatogonial stem cell transplantation in domestic cat as model for endangered felids

PTDC/CVT/119477/2010

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012/05/06 - 2015/09/05

Metabolic modulation as a tool to create and propagate pluripotent stem cell lines

PTDC/EBB-EBI/120634/2010

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2009/01/01 - 2011/12/31

Criação de um laboratório nacional de microarrays de DNA: Fase II

PTDC/BIA-BCM/64745/2006

Researcher

Universidade de Aveiro; Universidade de Aveiro Centro de Estudos do Ambiente e do Mar; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2006 - 2008

"Sperm function: What makes a good spermatozoon? A trans-specific perspective"

III/BIO/50/2005

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Instituto de Investigação Interdisciplinar

Funders: Universidade de Coimbra Instituto de Investigação Interdisciplinar

2005 - 2006

Functional characterization of equine sperm. A molecular evaluation of stallion fertility

POCTI/CVT/49102/2002

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2004 - 2005

"Mitochondrial bioenergetics and membrane dynamics during spermiogenesis and sperm function: Implication for human fertility."

POCTI/ESP/38049/2001

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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