Publications
Information about journal articles, updated at 22-12-2024, from platform CIÊNCIAVITAE.
SQSTM1 Pro392Leu presenting as a corticobasal syndrome with progressive nonfluent aphasia
Tábuas-Pereira, Miguel; Lima, Marisa; Bernardes, Catarina; Durães, João; Duro, Diana; Baldeiras, Ines; Freire-Gonçalves, António; et al, Parkinsonism & Related Disorders. 2024. http://dx.doi.org/10.1016/j.parkreldis.2024.106069 . 10.1016/j.parkreldis.2024.106069 . published Parkinsonism & Related Disorders
Exploring the potential of fully automated LUMIPULSE G plasma assays for detecting Alzheimer’s disease pathology
Silva-Spínola, Anuschka; Leitão, Maria João; Nadal, Alicia; Le Bastard, Nathalie; Santana, Isabel; Baldeiras, Ines, Alzheimer's Research & Therapy. 1. 16. 2024. http://dx.doi.org/10.1186/s13195-024-01397-9 . 10.1186/s13195-024-01397-9 . published Alzheimer's Research & Therapy
Neuropsychological Assessment in the Distinction Between Biomarker Defined Frontal-Variant of Alzheimer’s Disease and Behavioral-Variant of Frontotemporal Dementia
Lima, Marisa; Tábuas-Pereira, Miguel; Durães, João; Vieira, Daniela; Faustino, Pedro; Baldeiras, Ines; Santana, Isabel, Journal of Alzheimer's Disease. 1303 - 1312. 4. 91. 2023. http://dx.doi.org/10.3233/jad-220897 . 10.3233/jad-220897 . Journal of Alzheimer's Disease
Reconsidering the role of blood-brain barrier in Alzheimer’s disease: From delivery to target
Sousa, João André; Bernardes, Catarina; Bernardo-Castro, Sara; Lino, Miguel; Albino, Inês; Ferreira, Lino; Brás, José; et al, Frontiers in Aging Neuroscience. 15. 2023. http://dx.doi.org/10.3389/fnagi.2023.1102809 . 10.3389/fnagi.2023.1102809 . Frontiers in Aging Neuroscience
Associations between self-reported sleep quality and cerebrospinal fluid biomarkers in mild cognitive impairment and Alzheimer's disease
Durães, J.; Marques, P.; Novo, A.M.; Facas, J.; Duro, D.; Lima, M.; Leitão, M.J.; et al, Revue Neurologique. 877 - 881. 8. 179. 2023. http://dx.doi.org/10.1016/j.neurol.2022.12.009 . 10.1016/j.neurol.2022.12.009 . Revue Neurologique
Blood biomarkers in mild cognitive impairment patients: Relationship between analytes and progression to Alzheimer disease dementia
Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Bernardes, Catarina; Durães, João; Duro, Diana; Tábuas-Pereira, Miguel; Santana, Isabel; Baldeiras, Ines, European Journal of Neurology. 1565 - 1573. 6. 30. 2023. http://dx.doi.org/10.1111/ene.15762 . 10.1111/ene.15762 . European Journal of Neurology
The relevance of the socio-emotional deficits in cerebral small vessels disease (CSVD): An exploratory study with sporadic CSVD and CADASIL patients
Silva, Ana Rita; Santos, Irina; Fernandes, Carolina; Silva, Cristiana; Pereira, Daniela; Galego, Orlando; Queiroz, Henrique; et al, Cerebral Circulation - Cognition and Behavior. 5. 2023. http://dx.doi.org/10.1016/j.cccb.2023.100186 . 10.1016/j.cccb.2023.100186 . Cerebral Circulation - Cognition and Behavior
Serum Neurofilament Light Chain in the Diagnostic Evaluation of Patients with Cognitive Symptoms in the Neurological Consultation of a Tertiary Center
Lopes das Neves, Pedro; Durães, João; Silva-Spinola, Anuschka; Lima, Marisa; Leitão, Maria João; Tábuas-Pereira, Miguel; Santana, Isabel; Baldeiras, Ines, Journal of Alzheimer's Disease. 391 - 397. 2. 95. 2023. http://dx.doi.org/10.3233/jad-221208 . 10.3233/jad-221208 . Journal of Alzheimer's Disease
Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress
Grilo, Luís F.; Martins, João D.; Diniz, Mariana S.; Tocantins, Carolina; Cavallaro, Chiara H.; Baldeiras, Ines; Cunha-Oliveira, Teresa; et al, Clinical Science. 1347 - 1372. 17. 137. 2023. http://dx.doi.org/10.1042/cs20230048 . 10.1042/cs20230048 . Clinical Science
The decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes lung anticancer therapy due to a remodeling of mitochondrial metabolism and upregulation of energetic glycolytic dependence
Amorim, Ricardo; Magalhães, Carina; Benfeito, Sofia ; Ludgero Tavares; Santos, Kátia; Sardão, Vilma; Sandipan Datta; et al, Free Radical Biology and Medicine. 2023. submitted Free Radical Biology and Medicine
Montreal cognitive assessment in mild cognitive impairment: relationship with CSF biomarkers and conversion to dementia
Bernardes, Catarina; Lima, Marisa; Duro, Diana; Silva-Spínola, Anuschka; Durães, João; Tábuas-Pereira, Miguel; Baldeiras, Ines; Freitas, Sandra; Santana, Isabel, Journal of Alzheimer's Disease. 2023. accepted Journal of Alzheimer's Disease
Characterization of Progranulin Gene Mutations in Portuguese Patients with Frontotemporal Dementia
Maria Rosário Almeida; Miguel Tábuas-Pereira; Inês Baldeiras; Marisa Lima; João Durães; João Massano; Madalena Pinto; Catarina Cruto; Isabel Santana, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms25010511 . 10.3390/ijms25010511 . International Journal of Molecular Sciences
Mitochondrial respiration in thoracic perivascular adipose tissue of diabetic mice
Aryane Cruz Oliveira Pinho; Diana Santos; Inês Baldeiras; Ana Burgeiro; Emelindo C Leal; Eugenia Carvalho, Journal of Endocrinology. 2022. https://doi.org/10.1530/JOE-21-0446 . 10.1530/JOE-21-0446 . Journal of Endocrinology
The Road to Personalized Medicine in Alzheimer’s Disease: The Use of Artificial Intelligence
Anuschka Silva-Spínola; Inês Baldeiras; Joel P. Arrais; Isabel Santana, Biomedicines. 315 - 315. 2. 10. 2022. https://doi.org/10.3390/biomedicines10020315 . 10.3390/biomedicines10020315 . Biomedicines
Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers
Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-021-00955-9 . 10.1186/s13195-021-00955-9 . Alzheimer's Research & Therapy
Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis
Salazar, Ivan L.; Lourenço, Ana S. T.; Manadas, Bruno; Baldeiras, Inês; Ferreira, Cláudia; Teixeira, Anabela Claro; Mendes, Vera M.; et al, Journal of Neuroinflammation. 1. 19. 2022. http://dx.doi.org/10.1186/s12974-022-02404-2 . 10.1186/s12974-022-02404-2 . Journal of Neuroinflammation
Lewy body dementia is associated with an increased risk of atrial fibrillation: A case-control study
Tábuas-Pereira, Miguel; Durães, João; Beato-Coelho, José; Rita Nogueira, Ana; Duro, Diana; Baldeiras, Inês; Santana, Isabel, Journal of Clinical Neuroscience. 62 - 65. 99. 2022. http://dx.doi.org/10.1016/j.jocn.2022.02.038 . 10.1016/j.jocn.2022.02.038 . Journal of Clinical Neuroscience
Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases
Schmitz, Matthias; Villar-Piqué, Anna; Hermann, Peter; Escaramís, Geòrgia; Calero, Miguel; Chen, Cao; Kruse, Niels; et al, Brain. 700 - 712. 2. 145. 2022. http://dx.doi.org/10.1093/brain/awab350 . 10.1093/brain/awab350 . Brain
Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage
Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine
Serum GFAP differentiates Alzheimer’s disease from frontotemporal dementia and predicts MCI-to-dementia conversion
Patrick Oeckl; Sarah Anderl-Straub; Christine A F Von Arnim; Inês Baldeiras; Janine Diehl-Schmid; Timo Grimmer; Steffen Halbgebauer; et al, Journal of Neurology, Neurosurgery & Psychiatry. 2022. https://doi.org/10.1136/jnnp-2021-328547 . 10.1136/jnnp-2021-328547 . Journal of Neurology, Neurosurgery & Psychiatry
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum
Jansen, Willemijn J.; Janssen, Olin; Tijms, Betty M.; Vos, Stephanie J. B.; Ossenkoppele, Rik; Visser, Pieter Jelle; Aarsland, Dag; et al, JAMA Neurology. 3. 79. 2022. http://dx.doi.org/10.1001/jamaneurol.2021.5216 . 10.1001/jamaneurol.2021.5216 . JAMA Neurology
Exome Sequencing of a Portuguese Cohort of Frontotemporal Dementia Patients: Looking Into the ALS-FTD Continuum
Tábuas-Pereira, Miguel; Santana, Isabel; Gibbons, Elizabeth; Paquette, Kimberly; Almeida, Maria Rosário; Baldeiras, Ines; Bras, Jose; Guerreiro, Rita, Frontiers in Neurology. 13. 2022. http://dx.doi.org/10.3389/fneur.2022.886379 . 10.3389/fneur.2022.886379 . Frontiers in Neurology
Alzheimer’s Disease Diagnosis Based on the Amyloid, Tau, and Neurodegeneration Scheme (ATN) in a Real-Life Multicenter Cohort of General Neurological Centers
Baldeiras, Ines; Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Vieira, Daniela; Tábuas-Pereira, Miguel; et al, Journal of Alzheimer's Disease. 419 - 432. 1. 90. 2022. http://dx.doi.org/10.3233/jad-220587 . 10.3233/jad-220587 . Journal of Alzheimer's Disease
In vivo molecular imaging of the neuroinflammatory response to peripheral acute bacterial infection in older patients with cognitive dysfunction: A cross-sectional controlled study
Silva, Ana Rita; Regueira, Patricia; Peres, André; Cardoso, Ana Luísa; Baldeiras, Ines; Santana, Isabel; Cerejeira, Joaquim, Frontiers in Aging Neuroscience. 14. 2022. http://dx.doi.org/10.3389/fnagi.2022.984178 . 10.3389/fnagi.2022.984178 . Frontiers in Aging Neuroscience
Peripheral inflammatory markers during an acute bacterial infection in older patients with and without cognitive dysfunction: A case control study
Regueira, Patrícia; Silva, Ana Rita; Cardoso, Ana Luísa; Cardoso, Ana Maria; Baldeiras, Ines; Santana, Isabel; Cerejeira, Joaquim, Brain, Behavior, & Immunity - Health. 25. 2022. http://dx.doi.org/10.1016/j.bbih.2022.100503 . 10.1016/j.bbih.2022.100503 . Brain, Behavior, & Immunity - Health
Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations
Cunha-Oliveira, Teresa; Silva, Daniela Franco; Segura, Luis; Baldeiras, Ines; Marques, Ricardo; Rosenstock, Tatiana; Oliveira, Paulo J.; Silva, Filomena S. G., European Journal of Clinical Investigation. 9. 52. 2022. http://dx.doi.org/10.1111/eci.13798 . 10.1111/eci.13798 . European Journal of Clinical Investigation
Cognitive trajectories following acute infection in older patients with and without cognitive impairment: an one-year follow-up study
Costa Silva, Ana Rita; Regueira, Patrícia; Cardoso, Ana; Baldeiras, Ines; Santana, Isabel; Cerejeira, Joaquim, Frontiers in Psychiatry. 2022. in press Frontiers in Psychiatry
Neuropsychological features of progranulin-associated frontotemporal dementia: A nested case-control study
Lima, M.; Tábuas-Pereira, M.; Duro, D.; Durães, J.; Vieira, D.; Baldeiras, I.; Almeida, M.; Santana, I., Neural Regeneration Research. 910 - 915. 5. 16. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097076140&partnerID=MN8TOARS . 10.4103/1673-5374.297082 . Neural Regeneration Research
Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction
Susana P. Pereira; Ludgero C. Tavares; Ana I. Duarte; Inês Baldeiras; Teresa Cunha-Oliveira; João D. Martins; Maria S. Santos; et al, Clinical Science. 2021. https://doi.org/10.1042/CS20201339 . 10.1042/CS20201339 . Clinical Science
Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial Frontotemporal dementia
Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Santana, Isabel; Baldeiras, Inês, European Journal of Neurology. 2021. http://dx.doi.org/10.1111/ene.15058 . 10.1111/ene.15058 . European Journal of Neurology
Vasculitic peripheral neuropathy in deficiency of adenosine deaminase 2
Carneiro, Diogo Reis; Rebelo, Olinda; Matos, Anabela; Baldeiras, Inês; Almendra, Luciano; Fernandes, Carolina; Negrão, Luís; et al, Neuromuscular Disorders. 2021. http://dx.doi.org/10.1016/j.nmd.2021.05.001 . 10.1016/j.nmd.2021.05.001 . Neuromuscular Disorders
Oxidative Stress Parameters Can Predict the Response to Erythropoiesis-Stimulating Agents in Myelodysplastic Syndrome Patients
Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Jorge, Joana; Marques, Bárbara; Paiva, Artur; Oliveiros, Bárbara; et al, Frontiers in Cell and Developmental Biology. 9. 2021. http://dx.doi.org/10.3389/fcell.2021.701328 . 10.3389/fcell.2021.701328 . Frontiers in Cell and Developmental Biology
DNA Methylation Is Correlated with Oxidative Stress in Myelodysplastic Syndrome—Relevance as Complementary Prognostic Biomarkers
Ana Cristina Gonçalves; Raquel Alves; Inês Baldeiras; Bárbara Marques; Bárbara Oliveiros; Amélia Pereira; José Manuel Nascimento Costa; et al, Cancers. 3138 - 3138. 13. 13. 2021. https://doi.org/10.3390/cancers13133138 . 10.3390/cancers13133138 . Cancers
Cognitive Trajectories Following Acute Infection in Older Patients With and Without Cognitive Impairment: An 1-Year Follow-Up Study
Frontiers in Psychiatry. 12. 2021. http://dx.doi.org/10.3389/fpsyt.2021.754489 . 10.3389/fpsyt.2021.754489 . Frontiers in Psychiatry
Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-Analysis
Silva, Ana Rita; Regueira, Patrícia; Albuquerque, Elisabete; Baldeiras, Inês; Cardoso, Ana Luísa; Santana, Isabel; Cerejeira, Joaquim; et al, Journal of the American Medical Directors Association. 613 - 620.e9. 3. 22. 2021. http://dx.doi.org/10.1016/j.jamda.2020.08.017 . 10.1016/j.jamda.2020.08.017 . Journal of the American Medical Directors Association
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia
Llorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel; et al, Nature Communications. 1. 11. 2020. http://dx.doi.org/10.1038/s41467-020-14373-2 . 10.1038/s41467-020-14373-2 . Nature Communications
Neuropsychological Contribution to Predict Conversion to Dementia in Patients with Mild Cognitive Impairment Due to Alzheimer’s Disease
Silva, Dina; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Mendes, Tiago; Alves, Luísa; Nogueira, Joana; et al, Journal of Alzheimer's Disease. 1 - 12. 2020. http://dx.doi.org/10.3233/jad-191133 . 10.3233/jad-191133 . Journal of Alzheimer's Disease
A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid ß-amyloid42, total-tau, phospho-tau and a-synuclein in the differential diagnosis of neurodegenerative dementia
Diaz-Lucena, Daniela; Escaramis, Geòrgia; Villar-Piqué, Anna; Hermann, Peter; Schmitz, Matthias; Varges, Daniela; Santana, Isabel; et al, Journal of Neurology. 2567 - 2581. 9. 267. 2020. http://dx.doi.org/10.1007/s00415-020-09870-9 . 10.1007/s00415-020-09870-9 . published Journal of Neurology
Patients with progranulin mutations overlap with the progressive dysexecutive syndrome: towards the definition of a frontoparietal dementia phenotype
Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Duro, Diana; Lima, Marisa; Durães, João; Guerreiro, Rita; Brás, José; Baldeiras, Inês; Santana, Isabel, Brain Communications. 2. 2. 2020. http://dx.doi.org/10.1093/braincomms/fcaa126 . 10.1093/braincomms/fcaa126 . published Brain Communications
APOE ¿4-TOMM40L Haplotype Increases the Risk of Mild Cognitive Impairment Conversion to Alzheimer's Disease
Cardoso, R.; Lemos, C.; Oliveiros, B.; Almeida, M.R.; Baldeiras, I.; Pereira, C.F.; Santos, A.; et al, Journal of Alzheimer's Disease. 587 - 601. 2. 78. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096134035&partnerID=MN8TOARS . 10.3233/JAD-200556 . Journal of Alzheimer's Disease
A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson’s disease potential biomarkers
Anjo, Sandra I.; dos Santos, Patrícia Valério; Rosado, Luiza; Baltazar, Graça; Baldeiras, Inês; Pires, Diana; Gomes, Andreia; et al, Translational Neurodegeneration. 1. 9. 2020. http://dx.doi.org/10.1186/s40035-020-00188-0 . 10.1186/s40035-020-00188-0 . Translational Neurodegeneration
Increased c-x-c motif chemokine ligand 12 levels in cerebrospinal fluid as a candidate biomarker in sporadic amyotrophic lateral sclerosis
Andrés-Benito, P.; Povedano, M.; Domínguez, R.; Marco, C.; Colomina, M.J.; López-Pérez, Ó.; Santana, I.; et al, International Journal of Molecular Sciences. 1 - 21. 22. 21. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096189436&partnerID=MN8TOARS . 10.3390/ijms21228680 . International Journal of Molecular Sciences
C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia
Fernandes, A.; Tábuas-Pereira, M.; Duro, D.; Lima, M.; Gens, H.; Santiago, B.; Durães, J.; et al, Experimental Gerontology. 138. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85086792594&partnerID=MN8TOARS . 10.1016/j.exger.2020.111004 . Experimental Gerontology
Neuropsychological profile of amyloid-positive versus amyloid-negative amnestic Mild Cognitive Impairment
Alves, L.; Cardoso, S.; Silva, D.; Mendes, T.; Marôco, J.; Nogueira, J.; Lima, M.; et al, Journal of Neuropsychology. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087142245&partnerID=MN8TOARS . 10.1111/jnp.12218 . Journal of Neuropsychology
PBMCs as a potential source of biomarkers in neurodegenerative diseases – preliminary study
Anjo, Sandra; Silva, Rafael; Baldeiras, Ines; Mendonça, Alexandre; Januário, Cristina; Santana, Isabel; Verdelho, Ana; et al, Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/conf.fncel.2019.01.00001 . 10.3389/conf.fncel.2019.01.00001 . published Frontiers in Cellular Neuroscience
Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients
Zerr, Inga; Villar-Piqué, Anna; Schmitz, Vanda Edit; Poleggi, Anna; Pocchiari, Maurizio; Sánchez-Valle, Raquel; Calero, Miguel; et al, Biomolecules. 12. 9. 2019. http://dx.doi.org/10.3390/biom9120800 . 10.3390/biom9120800 . Biomolecules
Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study
van Maurik, I.S.; Vos, S.J.; Bos, I.; Bouwman, F.H.; Teunissen, C.E.; Scheltens, P.; Barkhof, F.; et al, The Lancet Neurology. 1034 - 1044. 11. 18. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072867961&partnerID=MN8TOARS . 10.1016/S1474-4422(19)30283-2 . The Lancet Neurology
Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease
Tábuas-Pereira, Miguel; Durães, João; Lopes, Joana; Sales, Francisco; Bento, Conceição; Duro, Diana; Santiago, Beatriz; et al, Epilepsy & Behavior. 207 - 209. 98. 2019. http://dx.doi.org/10.1016/j.yebeh.2019.06.033 . 10.1016/j.yebeh.2019.06.033 . Epilepsy & Behavior
Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer’s disease
Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Vieira, Daniela; Duro, Diana; Mroczko, Barbara; Kornhuber, Johannes; Lewczuk, Piotr, Alzheimer's Research & Therapy. 1. 11. 2019. http://dx.doi.org/10.1186/s13195-018-0456-x . 10.1186/s13195-018-0456-x . Alzheimer's Research & Therapy
Lower CSF Amyloid-Beta1–42 Predicts a Higher Mortality Rate in Frontotemporal Dementia
Vieira, Daniela; Durães, João; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Lima, Marisa; Leitão, Maria João; Tábuas-Pereira, Miguel; Santana, Isabel, Diagnostics. 4. 9. 2019. http://dx.doi.org/10.3390/diagnostics9040162 . 10.3390/diagnostics9040162 . Diagnostics
CSF IgG oligoclonal bands and prognosis in multiple sclerosis
Valado, A; Sousa, L; Baldeiras, I, European Journal of Public Health. Supplement. 29. 2019. http://dx.doi.org/10.1093/eurpub/ckz034.016 . 10.1093/eurpub/ckz034.016 . European Journal of Public Health
Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer’s disease
Maria João Leitão; Anuschka Silva-Spínola; Isabel Santana; Veronica Olmedo; Alicia Nadal; Nathalie Le Bastard; Inês Baldeiras, Alzheimer's Research & Therapy. 2019. https://doi.org/10.1186/s13195-019-0550-8 . 10.1186/s13195-019-0550-8 . Alzheimer's Research & Therapy
Association between adipokines and biomarkers of Alzheimer's disease: A cross-sectional study
Letra, L.; Matafome, P.; Rodrigues, T.; Duro, D.; Lemos, R.; Baldeiras, I.; Patrcio, M.; et al, Journal of Alzheimer's Disease. 725 - 735. 2. 67. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060571460&partnerID=MN8TOARS . 10.3233/JAD-180669 . Journal of Alzheimer's Disease
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL): Caracterização do Espectro de Manifestações Clínicas e do Padrão de Transmissão Genética
C. Santo, Gustavo; Silva, Ana R.; Galego, Orlando; Fernandes, Carolina; Gomes, Inês; Machado, Rita; Correia, Inês; et al, Sinapse. 17 - 25. 1-2. 19. 2019. Sinapse
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL): Description of the Spectrum of Clinical Features and the Genetic Pattern of Transmission
Santo, Gustavo; Silva, Ana Rita; Galego, Orlando; Sousa Fernandes, Carolina; Gomes, Inês; Correia, Inês; Tábuas-Pereira, Miguel; et al, Sinapse. 2019. published Sinapse
Adenosine Deaminase Two and Immunoglobulin M Accurately Differentiate Adult Sneddon’s Syndrome of Unknown Cause
Santo, Gustavo C.; Baldeiras, Inês; Guerreiro, Rita; Ribeiro, Joana A.; Cunha, Rosário; Youngstein, Taryn; Nanthapisal, Sira; et al, Cerebrovascular Diseases. 257 - 264. 5-6. 46. 2018. http://dx.doi.org/10.1159/000495794 . 10.1159/000495794 . Cerebrovascular Diseases
Association of Cerebral Amyloid-ß Aggregation With Cognitive Functioning in Persons Without Dementia
Jansen, Willemijn J.; Ossenkoppele, Rik; Tijms, Betty M.; Fagan, Anne M.; Hansson, Oskar; Klunk, William E.; van der Flier, Wiesje M.; et al, JAMA Psychiatry. 1. 75. 2018. http://dx.doi.org/10.1001/jamapsychiatry.2017.3391 . 10.1001/jamapsychiatry.2017.3391 . JAMA Psychiatry
Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases
Zerr, Inga; Schmitz, Matthias; Karch, André; Villar-Piqué, Anna; Kanata, Eirini; Golanska, Ewa; Díaz-Lucena, Daniela; et al, Alzheimer's & Dementia. 751 - 763. 6. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2017.12.008 . 10.1016/j.jalz.2017.12.008 . Alzheimer's & Dementia
Underlying Biological Processes in Mild Cognitive Impairment: Amyloidosis Versus Neurodegeneration
Santana, Isabel; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Freitas, Sandra; Pereira, Miguel Tábuas; Almeida, Maria Rosário; et al, Journal of Alzheimer's Disease. S647 - S657. s1. 64. 2018. http://dx.doi.org/10.3233/jad-179908 . 10.3233/jad-179908 . Journal of Alzheimer's Disease
Prevalence of the apolipoprotein E e4 allele in amyloid ß positive subjects across the spectrum of Alzheimer's disease
Mattsson, Niklas; Groot, Colin; Jansen, Willemijn J.; Landau, Susan M.; Villemagne, Victor L.; Engelborghs, Sebastiaan; Mintun, Mark M.; et al, Alzheimer's & Dementia. 913 - 924. 7. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2018.02.009 . 10.1016/j.jalz.2018.02.009 . Alzheimer's & Dementia
The Head Turning Sign in Dementia and Mild Cognitive Impairment: Its Relationship to Cognition, Behavior, and Cerebrospinal Fluid Biomarkers
Durães, João; Tábuas-Pereira, Miguel; Araújo, Rui; Duro, Diana; Baldeiras, Inês; Santiago, Beatriz; Santana, Isabel, Dementia and Geriatric Cognitive Disorders. 42 - 49. 1-2. 46. 2018. http://dx.doi.org/10.1159/000486531 . 10.1159/000486531 . Dementia and Geriatric Cognitive Disorders
Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases
Villar-Piqué, Anna; Schmitz, Matthias; Lachmann, Ingolf; Karch, André; Calero, Olga; Stehmann, Christiane; Sarros, Shannon; et al, Molecular Neurobiology. 2811 - 2821. 4. 56. 2018. http://dx.doi.org/10.1007/s12035-018-1251-1 . 10.1007/s12035-018-1251-1 . Molecular Neurobiology
Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer’s Disease Cerebrospinal Fluid Biomarkers
Ramos de Matos, Mafalda; Ferreira, Catarina; Herukka, Sanna-Kaisa; Soininen, Hilkka; Janeiro, André; Santana, Isabel; Baldeiras, Inês; et al, Journal of Alzheimer's Disease. 639 - 652. 2. 66. 2018. http://dx.doi.org/10.3233/jad-180512 . 10.3233/jad-180512 . Journal of Alzheimer's Disease
Addition of the Aß42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer’s disease dementia in mild cognitive impairment
Inês Baldeiras; Isabel Santana; Maria João Leitão; Helena Gens; Rui Pascoal; Miguel Tábuas-Pereira; José Beato-Coelho; et al, Alzheimer's Research & Therapy. 1. 10. 2018. https://doi.org/10.1186/s13195-018-0362-2 . 10.1186/s13195-018-0362-2 . Alzheimer's Research & Therapy
Quantitative genetics validates previous genetic variants and identifies novel genetic players influencing Alzheimer's disease cerebrospinal fluid biomarkers
Ramos De Matos, M.; Ferreira, C.; Herukka, S.-K.; Soininen, H.; Janeiro, A.; Santana, I.; Baldeiras, I.; et al, Journal of Alzheimer's Disease. 639 - 652. 2. 66. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055989436&partnerID=MN8TOARS . 10.3233/JAD-180512 . Journal of Alzheimer's Disease
Influence of butyrylcholinesterase in progression of mild cognitive impairment to Alzheimer's disease
Gabriel, A.J.; Almeida, M.R.; Ribeiro, M.H.; Carneiro, D.; Valério, D.; Pinheiro, A.C.; Pascoal, R.; et al, Journal of Alzheimer's Disease. 1097 - 1105. 3. 61. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048206568&partnerID=MN8TOARS . 10.3233/JAD-170695 . Journal of Alzheimer's Disease
CEREBROSPINAL FLUID Aß42 AND TAU MEASUREMENT ON LUMIPULSE® G: ANALYTICAL VERIFICATION AND METHOD COMPARISON
Leitão, Maria João; Santana, Isabel; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês, Alzheimer's & Dementia. 7. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2018.06.286 . 10.1016/j.jalz.2018.06.286 . Alzheimer's & Dementia
Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with risk and clinical course the disease
Valado, A.; Leitão, M.J.; Martinho, A.; Pascoal, R.; Cerqueira, J.; Correia, I.; Batista, S.; Sousa, L.; Baldeiras, I., Multiple Sclerosis and Related Disorders. 71 - 76. 11. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006760578&partnerID=MN8TOARS . 10.1016/j.msard.2016.12.003 . Multiple Sclerosis and Related Disorders
Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment
Herukka, S.-K.; Simonsen, A.H.; Andreasen, N.; Baldeiras, I.; Bjerke, M.; Blennow, K.; Engelborghs, S.; et al, Alzheimer's and Dementia. 285 - 295. 3. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007323510&partnerID=MN8TOARS . 10.1016/j.jalz.2016.09.009 . Alzheimer's and Dementia
Development of a mitochondriotropic antioxidant based on caffeic acid: Proof of concept on cellular and mitochondrial oxidative stress models
Teixeira, J.; Cagide, F.; Benfeito, S.; Soares, P.; Garrido, J.; Baldeiras, I.; Ribeiro, J.A.; et al, Journal of Medicinal Chemistry. 7084 - 7098. 16. 60. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028330575&partnerID=MN8TOARS . 10.1021/acs.jmedchem.7b00741 . Journal of Medicinal Chemistry
Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia
Simonsen, A.H.; Herukka, S.-K.; Andreasen, N.; Baldeiras, I.; Bjerke, M.; Blennow, K.; Engelborghs, S.; et al, Alzheimer's and Dementia. 274 - 284. 3. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007289521&partnerID=MN8TOARS . 10.1016/j.jalz.2016.09.008 . Alzheimer's and Dementia
Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes
Van Waalwijk Van Doorn, L.J.C.; Gispert, J.D.; Kuiperij, H.B.; Claassen, J.A.H.R.; Arighi, A.; Baldeiras, I.; Blennow, K.; et al, Journal of Alzheimer's Disease. 543 - 555. 2. 56. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011320275&partnerID=MN8TOARS . 10.3233/JAD-160668 . Journal of Alzheimer's Disease
Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats
Moreira, A.C.; Silva, A.M.; Branco, A.F.; Baldeiras, I.; Pereira, G.C.; Seiça, R.; Santos, M.S.; Sardão, V.A., Journal of Functional Foods. 329 - 339. 34. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019053766&partnerID=MN8TOARS . 10.1016/j.jff.2017.05.002 . Journal of Functional Foods
The frequency and influence of dementia risk factors in prodromal Alzheimer's disease
Bos, I.; Vos, S.J.; Frölich, L.; Kornhuber, J.; Wiltfang, J.; Maier, W.; Peters, O.; et al, Neurobiology of Aging. 33 - 40. 56. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018725939&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2017.03.034 . Neurobiology of Aging
Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer's disease patients
Gabriel, A.J.; Almeida, M.R.; Ribeiro, M.H.; Durães, J.; Tábuas-Pereira, M.; Pinheiro, A.C.; Pascoal, R.; Santana, I.; Baldeiras, I., Neuroscience Letters. 101 - 106. 641. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012253710&partnerID=MN8TOARS . 10.1016/j.neulet.2017.01.036 . Neuroscience Letters
Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis
Gonçalves, A.C.; Alves, R.; Baldeiras, I.; Cortesão, E.; Carda, J.P.; Branco, C.C.; Oliveiros, B.; et al, Molecular Carcinogenesis. 130 - 148. 1. 56. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960156457&partnerID=MN8TOARS . 10.1002/mc.22478 . Molecular Carcinogenesis
Prognosis of Early-Onset <em>vs.</em> Late-Onset Mild Cognitive Impairment: Comparison of Conversion Rates and Its Predictors
Baldeiras, Ines, Geriatrics. 2016. http://www.mdpi.com/2308-3417/1/2/11 . 10.3390/geriatrics1020011 . Geriatrics
Corticobasal syndrome in a dementia outpatient clinic: From clinical phenomenology to etiological diagnosis | Síndrome corticobasal numa consulta de demências: Da fenomenologia clínica ao diagnóstico etiológico
Arenga, M.; Pereira, M.; Santiago, B.; Baldeiras, I.; Almeida, M.R.; Santana, I., Sinapse. 18 - 26. 1. 16. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026801394&partnerID=MN8TOARS . Sinapse
Sporadic Creutzfeldt-Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3¿ assay
Leitão, M.J.; Baldeiras, I.; Almeida, M.R.; Ribeiro, M.H.; Santos, A.C.; Ribeiro, M.; Tomás, J.; et al, Neuroscience. 398 - 407. 322. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960172114&partnerID=MN8TOARS . 10.1016/j.neuroscience.2016.02.057 . Neuroscience
Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic
Schmitz, M.; Ebert, E.; Stoeck, K.; Karch, A.; Collins, S.; Calero, M.; Sklaviadis, T.; et al, Molecular Neurobiology. 2189 - 2199. 4. 53. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928958024&partnerID=MN8TOARS . 10.1007/s12035-015-9167-5 . Molecular Neurobiology
CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt–Jakob disease suspected cases with inconclusive 14-3-3 result
Leitão, M.J.; Baldeiras, I.; Almeida, M.R.; Ribeiro, M.H.; Santos, A.C.; Ribeiro, M.; Tomás, J.; et al, Journal of Neurology. 1847 - 1861. 9. 263. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976407297&partnerID=MN8TOARS . 10.1007/s00415-016-8209-x . Journal of Neurology
Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation
Almeida, M.R.; Macário, M.C.; Ramos, L.; Baldeiras, I.; Ribeiro, M.H.; Santana, I., Neurobiology of Aging. 200.e1 - 200.e5. 41. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963540872&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2016.02.019 . Neurobiology of Aging
Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics
Lelental, N.; Brandner, S.; Kofanova, O.; Blennow, K.; Zetterberg, H.; Andreasson, U.; Engelborghs, S.; et al, Journal of Alzheimer's Disease. 51 - 64. 1. 52. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973131635&partnerID=MN8TOARS . 10.3233/JAD-150883 . Journal of Alzheimer's Disease
The central biobank and virtual biobank of BIOMARKAPD: A resource for studies on neurodegenerative diseases
Reijs, B.L.R.; Teunissen, C.E.; Goncharenko, N.; Betsou, F.; Blennow, K.; Baldeiras, I.; Brosseron, F.; et al, Frontiers in Neurology. OCT. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946561925&partnerID=MN8TOARS . 10.3389/fneur.2015.00216 . Frontiers in Neurology
Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-ß Levels in Patients with Alzheimer's Disease?
Travassos, M.; Santana, I.; Baldeiras, I.; Tsolaki, M.; Gkatzima, O.; Genc, S.; Yener, G.G.; et al, Journal of Alzheimer's Disease. 1069 - 1078. 4. 47. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939450783&partnerID=MN8TOARS . 10.3233/JAD-150374 . Journal of Alzheimer's Disease
Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study
Kruse, N.; Persson, S.; Alcolea, D.; Bahl, J.M.C.; Baldeiras, I.; Capello, E.; Chiasserini, D.; et al, Neurobiology of Aging. 2587 - 2596. 9. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940467315&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2015.05.003 . Neurobiology of Aging
Cerebrospinal fluid Aß40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease
Inês Baldeiras; Isabel Santana; Maria João Leitão; Maria Helena Ribeiro; Rui Pascoal; Diana Duro; Raquel Lemos; et al, Journal of the Neurological Sciences. 308 - 316. 1-2. 358. 2015. http://dx.doi.org/10.1016/j.jns.2015.09.022 . 10.1016/j.jns.2015.09.022 . Journal of the Neurological Sciences
Prevalence of cerebral amyloid pathology in persons without dementia: A meta-analysis
Jansen, W.J.; Ossenkoppele, R.; Knol, D.L.; Tijms, B.M.; Scheltens, P.; Verhey, F.R.J.; Visser, P.J.; et al, JAMA - Journal of the American Medical Association. 1924 - 1938. 19. 313. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937529452&partnerID=MN8TOARS . 10.1001/jama.2015.4668 . JAMA - Journal of the American Medical Association
Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells
Loureiro, R.; Magalhães-Novais, S.; Mesquita, K.A.; Baldeiras, I.; Sousa, I.S.; Tavares, L.C.; Barbosa, I.A.; Oliveira, P.J.; Vega-Naredo, I., Oncotarget. 17081 - 17096. 19. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938269913&partnerID=MN8TOARS . Oncotarget
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease
Mota, S.I.; Costa, R.O.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Chasing the effects of pre-analytical confounders - A multicenter study on CSF-AD biomarkers
Leitão, M.J.; Baldeiras, I.; Herukka, S.-K.; Pikkarainen, M.; Leinonen, V.; Simonsen, A.H.; Perret-Liaudet, A.; et al, Frontiers in Neurology. JUL. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940025040&partnerID=MN8TOARS . 10.3389/fneur.2015.00153 . Frontiers in Neurology
Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a portuguese cohort
Almeida, M.R.; Baldeiras, I.; Ribeiro, M.H.; Santiago, B.; Machado, C.; Massano, J.; Guimarães, J.; et al, Neurodegenerative Diseases. 214 - 223. 4. 13. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893838273&partnerID=MN8TOARS . 10.1159/000352022 . Neurodegenerative Diseases
Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes
Carvalho, C.; Correia, S.C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I., Current Neurovascular Research. 330 - 339. 4. 11. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925786114&partnerID=MN8TOARS . Current Neurovascular Research
Rapeseed oil-rich di, et alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics
Monteiro, J.P.; Pereira, C.V.; Silva, A.M.; Maciel, E.; Baldeiras, I.; Peixoto, F.; Domingues, M.R.; Jurado, A.S.; Oliveira, P.J., Archives of Toxicology. 2151 - 2163. 12. 87. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890550286&partnerID=MN8TOARS . 10.1007/s00204-013-1068-7 . Archives of Toxicology
Prodromal metabolic phenotype in MCI cybrids: Implications for Alzheimer's disease
Silva, D.F.; Santana, I.; Esteves, A.R.; Baldeiras, I.; Arduino, D.M.; Oliveira, C.R.; Cardoso, S.M., Current Alzheimer Research. 180 - 190. 2. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875000768&partnerID=MN8TOARS . 10.2174/1567205011310020008 . Current Alzheimer Research
Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance
Cardoso, S.; Santos, R.X.; Correia, S.C.; Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I., Neurobiology of Disease. 1 - 12. 1. 49. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866491588&partnerID=MN8TOARS . 10.1016/j.nbd.2012.08.008 . Neurobiology of Disease
Transthyretin decrease in plasma of MCI and AD patients: Investigation of mechanisms for disease modulation
Ribeiro, C.A.; Santana, I.; Oliveira, C.; Baldeiras, I.; Moreira, J.; Saraiva, M.J.; Cardoso, I., Current Alzheimer Research. 881 - 889. 8. 9. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867714724&partnerID=MN8TOARS . 10.2174/156720512803251057 . Current Alzheimer Research
Differentiation-dependent doxorubicin toxicity on h9c2 cardiomyoblasts
Branco, A.F.; Sampaio, S.F.; Moreira, A.C.; Holy, J.; Wallace, K.B.; Baldeiras, I.; Oliveira, P.J.; Sardão, V.A., Cardiovascular Toxicology. 326 - 340. 4. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870546889&partnerID=MN8TOARS . 10.1007/s12012-012-9177-8 . Cardiovascular Toxicology
CSF biomarkers for the early diagnosis of Alzheimer's disease in a routine clinical setting - The first Portuguese study | Biomarcadores do LCR no diagnóstico precoce da doença de Alzheimer em ambiente clínico de rotina - o primeiro estudo em Portugal
Baldeiras, I.; Santana, I.; Garrucho, M.H.; Pascoal, R.; Lemos, R.; Santiago, B.; de Oliveira, C.R., Sinapse. 14 - 22. 2. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872921979&partnerID=MN8TOARS . Sinapse
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities
Carvalho, C.; Cardoso, S.; Correia, S.C.; Santos, R.X.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I., Diabetes. 1234 - 1242. 5. 61. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860599622&partnerID=MN8TOARS . 10.2337/db11-1186 . Diabetes
Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase
Freitas, M.; Baldeiras, I.; Proença, T.; Alves, V.; Mota-Pinto, A.; Sarmento-Ribeiro, A., FEBS Open Bio. 119 - 128. 2. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862228730&partnerID=MN8TOARS . 10.1016/j.fob.2012.05.001 . FEBS Open Bio
Mitochondrial- and endoplasmic reticulum-associated oxidative stress in alzheimers disease: From pathogenesis to biomarkers
Ferreiro, E.; Baldeiras, I.; Ferreira, I.L.; Costa, R.O.; Rego, A.C.; Pereira, C.F.; Oliveira, C.R., International Journal of Cell Biology. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863688106&partnerID=MN8TOARS . 10.1155/2012/735206 . International Journal of Cell Biology
[Bilateral hyperintensity of the pulvinar and dorsomedial nucleus of the thalamus in sporadic Creutzfeldt-Jakob disease]. | Hiperintensidade bilateral do pulvinar e núcleo dorso-medial do tálamo na forma esporádica da doença de Creutzfeldt-Jakob.
Casimiro, C.; Martins, J.; Parreira, T.; Baldeiras, I.; Ribeiro, H.; Batista, S.; Machado, E.; et al, Acta médica portuguesa. 41 - 44. 25 Suppl 1. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891418124&partnerID=MN8TOARS . Acta médica portuguesa
Memory decline and cerebrospinal fluid biomarkers in MCI
Baldeiras, Ines; Lemos, Raquel; Cunha, Catarina; Ribeiro, Maria Helena; Santiago, Beatriz; Oliveira, Catarina; Santana, Isabel, Alzheimer's & Dementia. 4. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.909 . 10.1016/j.jalz.2011.05.909 . Alzheimer's & Dementia
Proteomics-Based technologies in the discovery of biomarkers for multiple sclerosis in the cerebrospinal fluid
Lourenço, A.S.T.; Baldeiras, I.; Grãos, M.; Duarte, C.B., Current Molecular Medicine. 326 - 349. 4. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958096423&partnerID=MN8TOARS . Current Molecular Medicine
Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung
Machado, N.G.; Baldeiras, I.; Pereira, G.C.; Pereira, S.P.; Oliveira, P.J., Chemico-Biological Interactions. 478 - 486. 3. 188. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78149466319&partnerID=MN8TOARS . 10.1016/j.cbi.2010.09.027 . Chemico-Biological Interactions
Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment
Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., Journal of Alzheimer's Disease. 1165 - 1177. 4. 21. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650467580&partnerID=MN8TOARS . 10.3233/JAD-2010-091723 . Journal of Alzheimer's Disease
Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes
Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I., Current Neurovascular Research. 288 - 300. 4. 7. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650657043&partnerID=MN8TOARS . Current Neurovascular Research
Oxidative damage and mitochondrial dysfunction in patients with mild cognitive impairment and Alzheimer's disease
Baldeiras, Inês; Santana, Isabel; Proença, Maria Teresa; Garrucho, Maria Helena; Pascoal, Rui; Rodrigues, Ana; Duro, Diana; et al, Alzheimer's & Dementia. S503 - S504. 4. 6. 2010. http://dx.doi.org/10.1016/j.jalz.2010.05.1679 . 10.1016/j.jalz.2010.05.1679 . Alzheimer's & Dementia
Sporadic Creutzfeldt-Jakob disease causing a 2-years slowly progressive isolated dementia
MacHado, A.; Ribeiro, M.; Rodrigues, M.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; Santana, I.; et al, Behavioural Neurology. 175 - 179. 3-4. 21. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-72949094841&partnerID=MN8TOARS . 10.3233/BEN-2009-0238 . Behavioural Neurology
Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients
Baldeiras, I.E.; Ribeiro, M.H.; Pacheco, P.; MacHado, Á.; Santana, I.; Cunha, L.; Oliveira, C.R., Journal of Neurology. 1540 - 1550. 9. 256. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-69549118450&partnerID=MN8TOARS . 10.1007/s00415-009-5160-0 . Journal of Neurology
Variant Creutzfeldt-Jacob disease: The second case in Portugal and in the same geographical region
Machado, Á.; Soares, H.; Antunes, H.; Magalhães, Z.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; et al, Journal of Neurology, Neurosurgery and Psychiatry. 180 - 182. 2. 79. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849188806&partnerID=MN8TOARS . 10.1136/jnnp.2007.128389 . Journal of Neurology, Neurosurgery and Psychiatry
Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K ATP channels
Rosário, L.M.; Barbosa, R.M.; Antunes, C.M.; Baldeiras, I.E.; Silva, A.M.; Tomé, Â.R.; Santos, R.M., Endocrine Journal. 639 - 650. 4. 55. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-51449090932&partnerID=MN8TOARS . 10.1507/endocrj.K07E-131 . Endocrine Journal
Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease
Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., Journal of Alzheimer's Disease. 117 - 128. 1. 15. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449117220&partnerID=MN8TOARS . Journal of Alzheimer's Disease
Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet
Machado, M.V.; Ravasco, P.; Jesus, L.; Marques-Vidal, P.; Oliveira, C.R.; Proença, T.; Baldeiras, I.; Camilo, M.E.; Cortez-Pinto, H., Scandinavian Journal of Gastroenterology. 95 - 102. 1. 43. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-37549069361&partnerID=MN8TOARS . 10.1080/00365520701559003 . Scandinavian Journal of Gastroenterology
Lamotrigine pharmacokinetic evaluation in epileptic patients submitted to VEEG monitoring
Almeida, A.M.; Falcão, A.C.; Sales, F.; Baldeiras, I.; Rocha, M.J.; Caramona, M.M., European Journal of Clinical Pharmacology. 737 - 742. 9. 62. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747888290&partnerID=MN8TOARS . 10.1007/s00228-006-0144-9 . European Journal of Clinical Pharmacology
Protein kinase C isoform specificity of cholinergic potentiation of glucose-induced pulsatile 5-HT/insulin release from mouse pancreatic islets
Baldeiras, I.E.; Santos, R.M.; Rosário, L.M., Biological Research. 531 - 539. 3. 39. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751108741&partnerID=MN8TOARS . Biological Research
5 117 out of 117 Publications
All projects
Information of exclusive responsibility of the researcher 22-12-2024 , from platform CIÊNCIAVITAE.
2023/03 - 2024/10
Barrier2AD - Targeting the Blood-Brain Barrier in Alzheimer's disease
2022.08902.PTDC
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2023 - 2025
BIOMINDER project - Metacognition in Frontotemporal dementia: correlation with neuropsychological findings and disease biomarkers
2022-15053.CBM
Researcher
Universidade de Coimbra Faculdade de Psicologia e de Ciências da Educação
Funders: Fundação para a Ciência e a Tecnologia
2023/10/01 - 2026/09/30
iLoF: nova plataforma de rastreio precoce e diferencial da doença de Alzheimer através da análise de plasma humano
N/A
Researcher
Centro Hospitalar e Universitário de Coimbra EPE
Funders: Roche International Ltda
2022 - 2023
Neutrophils infiltration through blood-brain barrier in traumatic brain injury: Role of CXCL8
EXPL/MED-PAT/0660/2021
Researcher
Universidade de Coimbra Faculdade de Medicina
Funders: Fundação para a Ciência e a Tecnologia
2022 - 2025
Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2022/01 - 2023/06
Non-invasive biomarkers of brain AD pathology at pre-dementia stages
EXPL/MEC-NEU/0192/2021
Principal investigator
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2023
Evaluating the impact of high-efficacy treatments on disease control in early MS: beyond NEDA
N/A
Researcher
2021/09 - 2022/12
Optical fingerprinting as a new tool for stratification of Alzheimer’s disease patients using blood-derived samples
N/A
Principal investigator
2021 - 2024
Assessing the value of serum Neurofilament light chain as biomarkers of response to first-line oral treatments in Multiple Sclerosis
NA
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Biogen Inc
2021/01/01 - 2021/12/31
Screening for neurodegeneration in an elderly cohort from the community: blood Neurofilament light chain as a tool to identify individuals at risk of cognitive decline
NA
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Grupo de Estudos de Envelhecimento Cerebral e Demencia
2021/01/01 - 2023/12/31
Disease modelling of frontotemporal dementia in human brain organoids
PTDC/MEC-NEU/4814/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2024
Assessing the value of serum Neurofilament light chain as biomarkers of response to first-line oral treatments in Multiple Sclerosis
NA
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Biogen Inc
2019 - 2022
Emerging MS therapies to the test: tracking immune cell trafficking, induced molecular mechanisms and aftermath effects
GZ-2017-11730
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Sanofi Genzyme
2018 - 2021
Affective disorders: biomarkers and early detection
POCI-01-0145-FEDER-30943
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2021
Beyond Beta-Amyloid - Deciphering Early Pathogenic Changes in Alzheimer's disease
PTDC/MED-NEU/27946/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2017 - 2018
New BACE1 inhibitors for the treatment of Alzheimer's disease: an approach for the development of effective and safe substrate-selective inhibitors
NA
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Grupo de Estudos de Envelhecimento Cerebral e Demencia
2017 - 2020
Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan
SAICTPAC/0010/2015
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2016 - 2019
Novel cerebrospinal fluid and serum biomarkers for Multiple Sclerosis
RG-1601-07502
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: National Multiple Sclerosis Society
2016 - 2019
Schizophrenia diagnosis and prognosis: finding the way to a personalized medicine’’
PTDC/NEU-SCC/7051/2014
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2015
BIOMARKAPD: Biomarkers for Alzheimer´s disease and Parkinson’s disease
JPND/0005/2011
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2015
DEMTEST: Biomarker based diagnosis of rapid progressive dementias – optimisation of diagnostic protocols
JPND/0001/2011
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2009 - 2012
Early Diagnosis of Alzheimer´s Disease: evaluation of recent classification criteria and proposal of new diagnostic tools
PIC/IC/83206/2007
Researcher
Centro Hospitalar e Universitário de Coimbra EPE
Funders: Fundação para a Ciência e a Tecnologia
2007 - 2010
Identification of biomarkers for Multiple Sclerosis in the cerebrospinal fluid and serum
NA
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Biogen-Idec
2007 - 2009
Disrupção da barreira hemato-encefálica na Esclerose Múltipla
NA
Principal investigator
Centro Hospitalar e Universitário de Coimbra EPE
Funders: Biogen-Idec
2005 - 2008
Neo-neurogenesis and Microglia in Temporal Lobe Epilesy: Role of Pro-inflammatory Cytokines and Neuropeptide Y in Neuroprotection of New Neurons
POCTI/SAU-FCF/58492/2004
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2001 - 2003
KATP channel-dependent and independent pathways in pancreatic beta-cells from normal and non-obese type-3 diabetic rodents
POCTI/NSE/42123/2001
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
1998 - 2001
Molecular and ionic mechanisms underlying pulsatile insulin secretion
PRAXIS/C/SAU/1318/98
Research Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
5 27 out of 27 projects
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